The role of mechanotransduction in heart failure pathobiology—a concise review

This review evaluates the role of mechanotransduction (MT) in heart failure (HF) pathobiology. Cardiac functional and structural modifications are regulated by biomechanical forces. Exposing cardiomyocytes and the myocardial tissue to altered biomechanical stress precipitates changes in the end-dias...

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Veröffentlicht in:	Heart failure reviews 2021-07, Vol.26 (4), p.981-995
Hauptverfasser:	Krueger, Wolfgang, Bender, Nicole, Haeusler, Martin, Henneberg, Maciej
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomechanics Cardiology Cardiomyocytes Congestive heart failure Heart failure Hypertrophy Mechanotransduction Medicine Medicine & Public Health Myocardium Phenotypes Structure-function relationships
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