Promotion of wound healing by acetate in murine colonic epithelial cell via c‐Jun N‐terminal kinase activation

Background and Aim Mucosal healing is an important clinical goal in patients with inflammatory bowel disease. Recently, short‐chain fatty acids (SCFAs) have been reported to have multifaceted effects to host. However, the effects of SCFAs on wound healing in intestinal epithelial cells are unclear....

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Veröffentlicht in:	Journal of gastroenterology and hepatology 2020-07, Vol.35 (7), p.1171-1179
Hauptverfasser:	Nakano, Takahiro, Uchiyama, Kazuhiko, Ushiroda, Chihiro, Kashiwagi, Saori, Toyokawa, Yuki, Mizushima, Katsura, Inoue, Ken, Dohi, Osamu, Okayama, Tetsuya, Yoshida, Naohisa, Katada, Kazuhiro, Kamada, Kazuhiro, Handa, Osamu, Ishikawa, Takeshi, Takagi, Tomohisa, Konishi, Hideyuki, Naito, Yuji, Itoh, Yoshito
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetate Acetic acid Actin Body weight Cell activation Colitis Colon Colonic epithelial cell Dextran Enzyme inhibitors Epithelial cells Fatty acids Inflammatory bowel disease Inflammatory bowel diseases Intestine JNK protein Kinases Mucosa Patients Protein kinase Rho-associated kinase Sodium sulfate Wound healing
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