IC261 suppresses progression of hepatocellular carcinoma in a casein kinase 1 δ/ε independent manner

Hepatocellular carcinoma (HCC) is one of the most deadly cancers worldwide that responds poorly to existing therapies. The Casein kinase 1 (CK1) isoforms CK1δ and CK1ε are reported to be highly expressed in several tumor types, and both genetic and pharmacological inhibition of CK1δ/ε activity has d...

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Veröffentlicht in:	Biochemical and biophysical research communications 2020-03, Vol.523 (3), p.809-815
Hauptverfasser:	Yuan, Feifei, Li, Donghe, Guo, Mengzhou, Fang, Tingting, Sun, Jialei, Qi, Feng, Rao, Qianwen, Zhao, Zhiying, Huang, Peixin, Yang, Biwei, Xia, Jinglin
Format:	Artikel
Sprache:	eng
Schlagworte:	Casein kinase 1 δ/ε Cell cycle Centrosome fragmentation Hepatocellular carcinoma IC261
Online-Zugang:	Volltext
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