The challenge of detecting modifications on proteins

Post-translational modifications (PTMs) are integral to the regulation of protein function, characterising their role in this process is vital to understanding how cells work in both healthy and diseased states. Mass spectrometry (MS) facilitates the mass determination and sequencing of peptides, an...

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Veröffentlicht in:	Essays in biochemistry 2020-02, Vol.64 (1), p.135-153
Hauptverfasser:	Smith, Lauren Elizabeth, Rogowska-Wrzesinska, Adelina
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Computational Biology Humans Mass Spectrometry Oxidation-Reduction Phosphorylation Protein Processing, Post-Translational Proteins - analysis Proteins - chemistry Proteins - metabolism
Online-Zugang:	Volltext
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