In vitro characterization of the thermoneutral transient receptor potential vanilloid-1 (TRPV1) inhibitor GRTE16523

The TRPV1 ion channel is a neuronal sensor that plays an important role in nociception and neuropathic as well as inflammatory pain. In clinical trials, hyperthermia and thermo-hypoaesthesia turned out as major side effects of TRPV1 antagonists, preventing successful development of such molecules as...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	European journal of pharmacology 2020-03, Vol.871, p.172934-172934, Article 172934
Hauptverfasser:	Damann, Nils, Bahrenberg, Gregor, Stockhausen, Hannelore, Habermann, Christopher J., Lesch, Bernhard, Frank-Foltyn, Robert, Lee, Jeewoo, Ann, Jihyae, Christoph, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics Body temperature regulation Hyperthermia TRPV1
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!