Physical activity and peak oxygen consumption are associated with walking in multiple sclerosis
•Walking performance defined using timed 25-foot walk and 6-minute walk tests.•Higher physical activity was associated with walking performance.•Higher peak oxygen consumption was associated with walking performance.•Together only physical activity was an independent contributor to walking performan...
Gespeichert in:
| Veröffentlicht in: | Multiple sclerosis and related disorders 2020-05, Vol.40, p.101941-101941, Article 101941 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 101941 |
|---|---|
| container_issue | |
| container_start_page | 101941 |
| container_title | Multiple sclerosis and related disorders |
| container_volume | 40 |
| creator | Hibner, Brooks A. Hilgenkamp, Thessa I.M. Schroeder, Elizabeth C. Motl, Robert W. Bollaert, Rachel E. Griffith, Garett Grigoriadis, Georgios Baynard, Tracy Fernhall, Bo |
| description | •Walking performance defined using timed 25-foot walk and 6-minute walk tests.•Higher physical activity was associated with walking performance.•Higher peak oxygen consumption was associated with walking performance.•Together only physical activity was an independent contributor to walking performance.
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system with a prevalence of nearly 1 million adults in the United States. MS results in declines in physical activity and peak oxygen consumption that might be independently associated with declines in walking performance. Therefore our purpose was to evaluate the association between physical activity and peak oxygen consumption with walking performance in individuals with MS.
Fifty individuals with MS between the ages of 18–70 yrs. (Female: 38; 46 ± 12 yrs.; BMI: 28.5 ± 6.4; EDSS: 3.3 [IQR: 2.5–4]) performed a maximal incremental cycle test to assess peak oxygen consumption (VO2peak), and wore an accelerometer for one week to measure moderate-to-vigorous physical activity (MVPA). Subjects further completed a timed 25-foot walk test (T25FW) and 6-minute walk (6MW) to measure walking performance.
MVPA and VO2peak were correlated with 6MW and T25FW (p |
| doi_str_mv | 10.1016/j.msard.2020.101941 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2341623984</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S2211034820300171</els_id><sourcerecordid>2341623984</sourcerecordid><originalsourceid>FETCH-LOGICAL-c359t-ba8c0715df768dd802459db2577d9446026df8743bf8c75839ec54f6c87cb66d3</originalsourceid><addsrcrecordid>eNp9kLtOBDEMRSMEAgT7BUgoJc0ueU-moECIl4QEBdRRJvFAlnmRZID9ewZ2ocSNLeva1z4IHVGyoISq0-WiTTb6BSPsp1MKuoX2GaN0TrhU23-10HtoltKSTKEkFYruoj1OSykYU_vIPLysUnC2wdbl8B7yCtvO4wHsK-4_V8_QYdd3aWyHHPoO2wjYptS7YDN4_BHyC_6wzWvonnHocDs2OQwN4OQaiH0K6RDt1LZJMNvkA_R0dfl4cTO_u7--vTi_mzsuyzyvrHakoNLXhdLea8KELH3FZFH4UghFmPK1LgSvau0KqXkJTopaOV24SinPD9DJeu8Q-7cRUjZtSA6axnbQj8kwLqhivNRikvK11E0Xpgi1GWJobVwZSsw3XLM0P3DNN1yzhjtNHW8MxqoF_zfzi3ISnK0FML35HiCa5AJ0DnyI4LLxffjX4AupK4x0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2341623984</pqid></control><display><type>article</type><title>Physical activity and peak oxygen consumption are associated with walking in multiple sclerosis</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Hibner, Brooks A. ; Hilgenkamp, Thessa I.M. ; Schroeder, Elizabeth C. ; Motl, Robert W. ; Bollaert, Rachel E. ; Griffith, Garett ; Grigoriadis, Georgios ; Baynard, Tracy ; Fernhall, Bo</creator><creatorcontrib>Hibner, Brooks A. ; Hilgenkamp, Thessa I.M. ; Schroeder, Elizabeth C. ; Motl, Robert W. ; Bollaert, Rachel E. ; Griffith, Garett ; Grigoriadis, Georgios ; Baynard, Tracy ; Fernhall, Bo</creatorcontrib><description>•Walking performance defined using timed 25-foot walk and 6-minute walk tests.•Higher physical activity was associated with walking performance.•Higher peak oxygen consumption was associated with walking performance.•Together only physical activity was an independent contributor to walking performance.
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system with a prevalence of nearly 1 million adults in the United States. MS results in declines in physical activity and peak oxygen consumption that might be independently associated with declines in walking performance. Therefore our purpose was to evaluate the association between physical activity and peak oxygen consumption with walking performance in individuals with MS.
Fifty individuals with MS between the ages of 18–70 yrs. (Female: 38; 46 ± 12 yrs.; BMI: 28.5 ± 6.4; EDSS: 3.3 [IQR: 2.5–4]) performed a maximal incremental cycle test to assess peak oxygen consumption (VO2peak), and wore an accelerometer for one week to measure moderate-to-vigorous physical activity (MVPA). Subjects further completed a timed 25-foot walk test (T25FW) and 6-minute walk (6MW) to measure walking performance.
MVPA and VO2peak were correlated with 6MW and T25FW (p < 0.05). When combined in multivariate regression analyses, VO2peak and MVPA were both significant contributors of T25FW speed and 6MW, but after controlling for sex and age, MVPA was the only significant contributor (β = 0.32 and β = 0.44, respectively).
Both higher MVPA and VO2peak were associated with better walking performance and in a combined model physical activity, but not peak oxygen consumption, remained an independent contributor to walking performance in individuals with MS. These results suggest that improving MVPA is a potential target for interventions to improve walking performance in persons with MS.</description><identifier>ISSN: 2211-0348</identifier><identifier>EISSN: 2211-0356</identifier><identifier>DOI: 10.1016/j.msard.2020.101941</identifier><identifier>PMID: 31954226</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Accelerometry ; Adolescent ; Adult ; Aged ; Assessment ; Exercise - physiology ; Exercise Test ; Female ; Fitness ; Humans ; Male ; Middle Aged ; Mobility ; Multiple Sclerosis - physiopathology ; Oxygen Consumption - physiology ; Physical Fitness - physiology ; Special populations ; Walking - physiology ; Young Adult</subject><ispartof>Multiple sclerosis and related disorders, 2020-05, Vol.40, p.101941-101941, Article 101941</ispartof><rights>2020 Elsevier B.V.</rights><rights>Copyright © 2020 Elsevier B.V. All rights reserved.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c359t-ba8c0715df768dd802459db2577d9446026df8743bf8c75839ec54f6c87cb66d3</citedby><cites>FETCH-LOGICAL-c359t-ba8c0715df768dd802459db2577d9446026df8743bf8c75839ec54f6c87cb66d3</cites><orcidid>0000-0001-9882-163X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31954226$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hibner, Brooks A.</creatorcontrib><creatorcontrib>Hilgenkamp, Thessa I.M.</creatorcontrib><creatorcontrib>Schroeder, Elizabeth C.</creatorcontrib><creatorcontrib>Motl, Robert W.</creatorcontrib><creatorcontrib>Bollaert, Rachel E.</creatorcontrib><creatorcontrib>Griffith, Garett</creatorcontrib><creatorcontrib>Grigoriadis, Georgios</creatorcontrib><creatorcontrib>Baynard, Tracy</creatorcontrib><creatorcontrib>Fernhall, Bo</creatorcontrib><title>Physical activity and peak oxygen consumption are associated with walking in multiple sclerosis</title><title>Multiple sclerosis and related disorders</title><addtitle>Mult Scler Relat Disord</addtitle><description>•Walking performance defined using timed 25-foot walk and 6-minute walk tests.•Higher physical activity was associated with walking performance.•Higher peak oxygen consumption was associated with walking performance.•Together only physical activity was an independent contributor to walking performance.
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system with a prevalence of nearly 1 million adults in the United States. MS results in declines in physical activity and peak oxygen consumption that might be independently associated with declines in walking performance. Therefore our purpose was to evaluate the association between physical activity and peak oxygen consumption with walking performance in individuals with MS.
Fifty individuals with MS between the ages of 18–70 yrs. (Female: 38; 46 ± 12 yrs.; BMI: 28.5 ± 6.4; EDSS: 3.3 [IQR: 2.5–4]) performed a maximal incremental cycle test to assess peak oxygen consumption (VO2peak), and wore an accelerometer for one week to measure moderate-to-vigorous physical activity (MVPA). Subjects further completed a timed 25-foot walk test (T25FW) and 6-minute walk (6MW) to measure walking performance.
MVPA and VO2peak were correlated with 6MW and T25FW (p < 0.05). When combined in multivariate regression analyses, VO2peak and MVPA were both significant contributors of T25FW speed and 6MW, but after controlling for sex and age, MVPA was the only significant contributor (β = 0.32 and β = 0.44, respectively).
Both higher MVPA and VO2peak were associated with better walking performance and in a combined model physical activity, but not peak oxygen consumption, remained an independent contributor to walking performance in individuals with MS. These results suggest that improving MVPA is a potential target for interventions to improve walking performance in persons with MS.</description><subject>Accelerometry</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Assessment</subject><subject>Exercise - physiology</subject><subject>Exercise Test</subject><subject>Female</subject><subject>Fitness</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mobility</subject><subject>Multiple Sclerosis - physiopathology</subject><subject>Oxygen Consumption - physiology</subject><subject>Physical Fitness - physiology</subject><subject>Special populations</subject><subject>Walking - physiology</subject><subject>Young Adult</subject><issn>2211-0348</issn><issn>2211-0356</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kLtOBDEMRSMEAgT7BUgoJc0ueU-moECIl4QEBdRRJvFAlnmRZID9ewZ2ocSNLeva1z4IHVGyoISq0-WiTTb6BSPsp1MKuoX2GaN0TrhU23-10HtoltKSTKEkFYruoj1OSykYU_vIPLysUnC2wdbl8B7yCtvO4wHsK-4_V8_QYdd3aWyHHPoO2wjYptS7YDN4_BHyC_6wzWvonnHocDs2OQwN4OQaiH0K6RDt1LZJMNvkA_R0dfl4cTO_u7--vTi_mzsuyzyvrHakoNLXhdLea8KELH3FZFH4UghFmPK1LgSvau0KqXkJTopaOV24SinPD9DJeu8Q-7cRUjZtSA6axnbQj8kwLqhivNRikvK11E0Xpgi1GWJobVwZSsw3XLM0P3DNN1yzhjtNHW8MxqoF_zfzi3ISnK0FML35HiCa5AJ0DnyI4LLxffjX4AupK4x0</recordid><startdate>202005</startdate><enddate>202005</enddate><creator>Hibner, Brooks A.</creator><creator>Hilgenkamp, Thessa I.M.</creator><creator>Schroeder, Elizabeth C.</creator><creator>Motl, Robert W.</creator><creator>Bollaert, Rachel E.</creator><creator>Griffith, Garett</creator><creator>Grigoriadis, Georgios</creator><creator>Baynard, Tracy</creator><creator>Fernhall, Bo</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-9882-163X</orcidid></search><sort><creationdate>202005</creationdate><title>Physical activity and peak oxygen consumption are associated with walking in multiple sclerosis</title><author>Hibner, Brooks A. ; Hilgenkamp, Thessa I.M. ; Schroeder, Elizabeth C. ; Motl, Robert W. ; Bollaert, Rachel E. ; Griffith, Garett ; Grigoriadis, Georgios ; Baynard, Tracy ; Fernhall, Bo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c359t-ba8c0715df768dd802459db2577d9446026df8743bf8c75839ec54f6c87cb66d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Accelerometry</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Assessment</topic><topic>Exercise - physiology</topic><topic>Exercise Test</topic><topic>Female</topic><topic>Fitness</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mobility</topic><topic>Multiple Sclerosis - physiopathology</topic><topic>Oxygen Consumption - physiology</topic><topic>Physical Fitness - physiology</topic><topic>Special populations</topic><topic>Walking - physiology</topic><topic>Young Adult</topic><toplevel>online_resources</toplevel><creatorcontrib>Hibner, Brooks A.</creatorcontrib><creatorcontrib>Hilgenkamp, Thessa I.M.</creatorcontrib><creatorcontrib>Schroeder, Elizabeth C.</creatorcontrib><creatorcontrib>Motl, Robert W.</creatorcontrib><creatorcontrib>Bollaert, Rachel E.</creatorcontrib><creatorcontrib>Griffith, Garett</creatorcontrib><creatorcontrib>Grigoriadis, Georgios</creatorcontrib><creatorcontrib>Baynard, Tracy</creatorcontrib><creatorcontrib>Fernhall, Bo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Multiple sclerosis and related disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hibner, Brooks A.</au><au>Hilgenkamp, Thessa I.M.</au><au>Schroeder, Elizabeth C.</au><au>Motl, Robert W.</au><au>Bollaert, Rachel E.</au><au>Griffith, Garett</au><au>Grigoriadis, Georgios</au><au>Baynard, Tracy</au><au>Fernhall, Bo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Physical activity and peak oxygen consumption are associated with walking in multiple sclerosis</atitle><jtitle>Multiple sclerosis and related disorders</jtitle><addtitle>Mult Scler Relat Disord</addtitle><date>2020-05</date><risdate>2020</risdate><volume>40</volume><spage>101941</spage><epage>101941</epage><pages>101941-101941</pages><artnum>101941</artnum><issn>2211-0348</issn><eissn>2211-0356</eissn><abstract>•Walking performance defined using timed 25-foot walk and 6-minute walk tests.•Higher physical activity was associated with walking performance.•Higher peak oxygen consumption was associated with walking performance.•Together only physical activity was an independent contributor to walking performance.
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system with a prevalence of nearly 1 million adults in the United States. MS results in declines in physical activity and peak oxygen consumption that might be independently associated with declines in walking performance. Therefore our purpose was to evaluate the association between physical activity and peak oxygen consumption with walking performance in individuals with MS.
Fifty individuals with MS between the ages of 18–70 yrs. (Female: 38; 46 ± 12 yrs.; BMI: 28.5 ± 6.4; EDSS: 3.3 [IQR: 2.5–4]) performed a maximal incremental cycle test to assess peak oxygen consumption (VO2peak), and wore an accelerometer for one week to measure moderate-to-vigorous physical activity (MVPA). Subjects further completed a timed 25-foot walk test (T25FW) and 6-minute walk (6MW) to measure walking performance.
MVPA and VO2peak were correlated with 6MW and T25FW (p < 0.05). When combined in multivariate regression analyses, VO2peak and MVPA were both significant contributors of T25FW speed and 6MW, but after controlling for sex and age, MVPA was the only significant contributor (β = 0.32 and β = 0.44, respectively).
Both higher MVPA and VO2peak were associated with better walking performance and in a combined model physical activity, but not peak oxygen consumption, remained an independent contributor to walking performance in individuals with MS. These results suggest that improving MVPA is a potential target for interventions to improve walking performance in persons with MS.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>31954226</pmid><doi>10.1016/j.msard.2020.101941</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0001-9882-163X</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2211-0348 |
| ispartof | Multiple sclerosis and related disorders, 2020-05, Vol.40, p.101941-101941, Article 101941 |
| issn | 2211-0348 2211-0356 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2341623984 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Accelerometry Adolescent Adult Aged Assessment Exercise - physiology Exercise Test Female Fitness Humans Male Middle Aged Mobility Multiple Sclerosis - physiopathology Oxygen Consumption - physiology Physical Fitness - physiology Special populations Walking - physiology Young Adult |
| title | Physical activity and peak oxygen consumption are associated with walking in multiple sclerosis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-07T16%3A20%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Physical%20activity%20and%20peak%20oxygen%20consumption%20are%20associated%20with%20walking%20in%20multiple%20sclerosis&rft.jtitle=Multiple%20sclerosis%20and%20related%20disorders&rft.au=Hibner,%20Brooks%20A.&rft.date=2020-05&rft.volume=40&rft.spage=101941&rft.epage=101941&rft.pages=101941-101941&rft.artnum=101941&rft.issn=2211-0348&rft.eissn=2211-0356&rft_id=info:doi/10.1016/j.msard.2020.101941&rft_dat=%3Cproquest_cross%3E2341623984%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2341623984&rft_id=info:pmid/31954226&rft_els_id=S2211034820300171&rfr_iscdi=true |