A New One‐Pot Fluorescence Derivatization Strategy for Highly Sensitive MicroRNA Analysis

MicroRNAs (miRNAs) modulate the expression of over 30 % of mammalian genes during development and apoptosis, and abnormal expression of miRNAs may lead to a range of human pathologies. Therefore, analysis of miRNAs is valuable for disease diagnostics. In this work, a novel one‐pot fluorescence deriv...

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Veröffentlicht in:	Chemistry : a European journal 2020-05, Vol.26 (25), p.5639-5647
Hauptverfasser:	Pan, Li, Zhang, Huaisheng, Zhao, Jingjin, Ogungbe, Ifedayo Victor, Zhao, Shulin, Liu, Yi‐Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaldehyde - analogs & derivatives Acetaldehyde - chemistry Adenine Adenine - chemistry Apoptosis Chemistry Chloroacetaldehyde Chromatography Chromatography, High Pressure Liquid - methods dyes/pigments Fluorescence Fluorescence spectroscopy Gene expression High performance liquid chromatography Humans Liquid chromatography magnetic properties Mass Spectrometry Mass spectroscopy MicroRNAs MicroRNAs - analysis miRNA Nucleic acids RNA recognition Spectrometry, Fluorescence - methods Strategy synthetic methods Water
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