A novel flunarizine hydrochloride-loaded organogel for intraocular drug delivery in situ: Design, physicochemical characteristics and inspection

[Display omitted] We developed a safe and efficacious drug delivery system for treatment of brain diseases. A novel in-situ gel system was prepared using soybean oil, stearic acid and N-methyl-2-pyrrolidinone (NMP) (10:1:3, v/w/v). This system had low viscosity as a sol in vitro and turned into a so...

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Veröffentlicht in:	International journal of pharmaceutics 2020-02, Vol.576, p.119027-119027, Article 119027
Hauptverfasser:	Dai, Manman, Bai, Luyu, Zhang, Huimin, Ma, Qun, Luo, Rui, Lei, Fang, Fei, Qingsong, He, Ning
Format:	Artikel
Sprache:	eng
Schlagworte:	Cumulative release Flunarizine hydrochloride Intraocular administration Organogel Pharmacokinetic Rheology
Online-Zugang:	Volltext
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