Diabetes mellitus and treatment outcomes of pulmonary tuberculosis: a cohort study
Objectives This study aimed to investigate the impact of diabetes on the treatment outcomes among pulmonary TB patients in Yerevan, Armenia. Methods We utilized a cohort study design that included TB patients with diabetes and TB patients without diabetes. The data collection was conducted in the Na...
Gespeichert in:
| Veröffentlicht in: | International journal of public health 2020-01, Vol.65 (1), p.37-43 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 43 |
|---|---|
| container_issue | 1 |
| container_start_page | 37 |
| container_title | International journal of public health |
| container_volume | 65 |
| creator | Sahakyan, Serine Petrosyan, Varduhi Abrahamyan, Lusine |
| description | Objectives
This study aimed to investigate the impact of diabetes on the treatment outcomes among pulmonary TB patients in Yerevan, Armenia.
Methods
We utilized a cohort study design that included TB patients with diabetes and TB patients without diabetes. The data collection was conducted in the National Tuberculosis Control Center, eight tuberculosis outpatient centers and the ‘Prisoners’ Hospital’ in Yerevan, Armenia. Data were collected from an existing national TB database and patients medical records. Multivariable logistic regressions were conducted to construct the final model and test the associations.
Results
The final sample included 621 patients 5.8% of whom had diabetes. The odds of having treatment failure was 8.99 times higher among TB patients with diabetes (95% confidence interval 2.51–32.23) compared to TB patients without diabetes after adjusting for weight and sputum smear status.
Conclusions
Diabetes comorbidity had a negative effect on TB treatment outcomes. Countries with a high burden of both TB and diabetes need to develop mechanisms for active screening for diabetes among patients with TB and address their treatment needs carefully. |
| doi_str_mv | 10.1007/s00038-019-01277-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2340044582</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2340044582</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-a79100e123eefb974a3388e0f031aaae991432545ab50c5a67cec6c070c31ee63</originalsourceid><addsrcrecordid>eNp9kEtr3DAURkVISSbT_oEsgiCbbNxePW13V_JqYaAQ0rWQNdeJg21N9FjMv6-mk0yhiy6EBPfok75DyDmDzwyg_hIBQDQVsLYsXtcVPyILpjWrGqXl8eGs9Ck5i_EFQEMD7IScCsYlCMEX5OFmsB0mjHTCcRxSjtTOa5oC2jThnKjPyfmpzH1PN3mc_GzDlqbcYXB59HGIX6mlzj_7kGhMeb39SD70doz46W1fkl93t4_X36vVz_sf199WlRO1SpWt29ICGReIfdfW0grRNAg9CGatxbZlUnAlle0UOGV17dBpBzU4wRC1WJKrfe4m-NeMMZlpiK60sDP6HA0XEkBK1fCCXv6Dvvgc5vI7w7nUSrQS2kLxPeWCjzFgbzZhmEpdw8DsjJu9cVOMmz_GzS764i06dxOuD1feFRdA7IFYRvMThr9v_yf2NzWei3Q</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2246539409</pqid></control><display><type>article</type><title>Diabetes mellitus and treatment outcomes of pulmonary tuberculosis: a cohort study</title><source>SpringerLink Journals - AutoHoldings</source><creator>Sahakyan, Serine ; Petrosyan, Varduhi ; Abrahamyan, Lusine</creator><creatorcontrib>Sahakyan, Serine ; Petrosyan, Varduhi ; Abrahamyan, Lusine</creatorcontrib><description>Objectives
This study aimed to investigate the impact of diabetes on the treatment outcomes among pulmonary TB patients in Yerevan, Armenia.
Methods
We utilized a cohort study design that included TB patients with diabetes and TB patients without diabetes. The data collection was conducted in the National Tuberculosis Control Center, eight tuberculosis outpatient centers and the ‘Prisoners’ Hospital’ in Yerevan, Armenia. Data were collected from an existing national TB database and patients medical records. Multivariable logistic regressions were conducted to construct the final model and test the associations.
Results
The final sample included 621 patients 5.8% of whom had diabetes. The odds of having treatment failure was 8.99 times higher among TB patients with diabetes (95% confidence interval 2.51–32.23) compared to TB patients without diabetes after adjusting for weight and sputum smear status.
Conclusions
Diabetes comorbidity had a negative effect on TB treatment outcomes. Countries with a high burden of both TB and diabetes need to develop mechanisms for active screening for diabetes among patients with TB and address their treatment needs carefully.</description><identifier>ISSN: 1661-8556</identifier><identifier>EISSN: 1661-8564</identifier><identifier>DOI: 10.1007/s00038-019-01277-2</identifier><identifier>PMID: 31240332</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Clinical outcomes ; Cohort analysis ; Diabetes ; Environmental Health ; Medical treatment ; Medicine ; Medicine & Public Health ; Occupational Medicine/Industrial Medicine ; Original Article ; Public Health ; Tuberculosis</subject><ispartof>International journal of public health, 2020-01, Vol.65 (1), p.37-43</ispartof><rights>Swiss School of Public Health (SSPH+) 2019</rights><rights>International Journal of Public Health is a copyright of Springer, (2019). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-a79100e123eefb974a3388e0f031aaae991432545ab50c5a67cec6c070c31ee63</citedby><cites>FETCH-LOGICAL-c375t-a79100e123eefb974a3388e0f031aaae991432545ab50c5a67cec6c070c31ee63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00038-019-01277-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00038-019-01277-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31240332$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sahakyan, Serine</creatorcontrib><creatorcontrib>Petrosyan, Varduhi</creatorcontrib><creatorcontrib>Abrahamyan, Lusine</creatorcontrib><title>Diabetes mellitus and treatment outcomes of pulmonary tuberculosis: a cohort study</title><title>International journal of public health</title><addtitle>Int J Public Health</addtitle><addtitle>Int J Public Health</addtitle><description>Objectives
This study aimed to investigate the impact of diabetes on the treatment outcomes among pulmonary TB patients in Yerevan, Armenia.
Methods
We utilized a cohort study design that included TB patients with diabetes and TB patients without diabetes. The data collection was conducted in the National Tuberculosis Control Center, eight tuberculosis outpatient centers and the ‘Prisoners’ Hospital’ in Yerevan, Armenia. Data were collected from an existing national TB database and patients medical records. Multivariable logistic regressions were conducted to construct the final model and test the associations.
Results
The final sample included 621 patients 5.8% of whom had diabetes. The odds of having treatment failure was 8.99 times higher among TB patients with diabetes (95% confidence interval 2.51–32.23) compared to TB patients without diabetes after adjusting for weight and sputum smear status.
Conclusions
Diabetes comorbidity had a negative effect on TB treatment outcomes. Countries with a high burden of both TB and diabetes need to develop mechanisms for active screening for diabetes among patients with TB and address their treatment needs carefully.</description><subject>Clinical outcomes</subject><subject>Cohort analysis</subject><subject>Diabetes</subject><subject>Environmental Health</subject><subject>Medical treatment</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Occupational Medicine/Industrial Medicine</subject><subject>Original Article</subject><subject>Public Health</subject><subject>Tuberculosis</subject><issn>1661-8556</issn><issn>1661-8564</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kEtr3DAURkVISSbT_oEsgiCbbNxePW13V_JqYaAQ0rWQNdeJg21N9FjMv6-mk0yhiy6EBPfok75DyDmDzwyg_hIBQDQVsLYsXtcVPyILpjWrGqXl8eGs9Ck5i_EFQEMD7IScCsYlCMEX5OFmsB0mjHTCcRxSjtTOa5oC2jThnKjPyfmpzH1PN3mc_GzDlqbcYXB59HGIX6mlzj_7kGhMeb39SD70doz46W1fkl93t4_X36vVz_sf199WlRO1SpWt29ICGReIfdfW0grRNAg9CGatxbZlUnAlle0UOGV17dBpBzU4wRC1WJKrfe4m-NeMMZlpiK60sDP6HA0XEkBK1fCCXv6Dvvgc5vI7w7nUSrQS2kLxPeWCjzFgbzZhmEpdw8DsjJu9cVOMmz_GzS764i06dxOuD1feFRdA7IFYRvMThr9v_yf2NzWei3Q</recordid><startdate>20200101</startdate><enddate>20200101</enddate><creator>Sahakyan, Serine</creator><creator>Petrosyan, Varduhi</creator><creator>Abrahamyan, Lusine</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>20200101</creationdate><title>Diabetes mellitus and treatment outcomes of pulmonary tuberculosis: a cohort study</title><author>Sahakyan, Serine ; Petrosyan, Varduhi ; Abrahamyan, Lusine</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-a79100e123eefb974a3388e0f031aaae991432545ab50c5a67cec6c070c31ee63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Clinical outcomes</topic><topic>Cohort analysis</topic><topic>Diabetes</topic><topic>Environmental Health</topic><topic>Medical treatment</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Occupational Medicine/Industrial Medicine</topic><topic>Original Article</topic><topic>Public Health</topic><topic>Tuberculosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sahakyan, Serine</creatorcontrib><creatorcontrib>Petrosyan, Varduhi</creatorcontrib><creatorcontrib>Abrahamyan, Lusine</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of public health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sahakyan, Serine</au><au>Petrosyan, Varduhi</au><au>Abrahamyan, Lusine</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diabetes mellitus and treatment outcomes of pulmonary tuberculosis: a cohort study</atitle><jtitle>International journal of public health</jtitle><stitle>Int J Public Health</stitle><addtitle>Int J Public Health</addtitle><date>2020-01-01</date><risdate>2020</risdate><volume>65</volume><issue>1</issue><spage>37</spage><epage>43</epage><pages>37-43</pages><issn>1661-8556</issn><eissn>1661-8564</eissn><abstract>Objectives
This study aimed to investigate the impact of diabetes on the treatment outcomes among pulmonary TB patients in Yerevan, Armenia.
Methods
We utilized a cohort study design that included TB patients with diabetes and TB patients without diabetes. The data collection was conducted in the National Tuberculosis Control Center, eight tuberculosis outpatient centers and the ‘Prisoners’ Hospital’ in Yerevan, Armenia. Data were collected from an existing national TB database and patients medical records. Multivariable logistic regressions were conducted to construct the final model and test the associations.
Results
The final sample included 621 patients 5.8% of whom had diabetes. The odds of having treatment failure was 8.99 times higher among TB patients with diabetes (95% confidence interval 2.51–32.23) compared to TB patients without diabetes after adjusting for weight and sputum smear status.
Conclusions
Diabetes comorbidity had a negative effect on TB treatment outcomes. Countries with a high burden of both TB and diabetes need to develop mechanisms for active screening for diabetes among patients with TB and address their treatment needs carefully.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>31240332</pmid><doi>10.1007/s00038-019-01277-2</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1661-8556 |
| ispartof | International journal of public health, 2020-01, Vol.65 (1), p.37-43 |
| issn | 1661-8556 1661-8564 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2340044582 |
| source | SpringerLink Journals - AutoHoldings |
| subjects | Clinical outcomes Cohort analysis Diabetes Environmental Health Medical treatment Medicine Medicine & Public Health Occupational Medicine/Industrial Medicine Original Article Public Health Tuberculosis |
| title | Diabetes mellitus and treatment outcomes of pulmonary tuberculosis: a cohort study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T17%3A03%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Diabetes%20mellitus%20and%20treatment%20outcomes%20of%20pulmonary%20tuberculosis:%20a%20cohort%20study&rft.jtitle=International%20journal%20of%20public%20health&rft.au=Sahakyan,%20Serine&rft.date=2020-01-01&rft.volume=65&rft.issue=1&rft.spage=37&rft.epage=43&rft.pages=37-43&rft.issn=1661-8556&rft.eissn=1661-8564&rft_id=info:doi/10.1007/s00038-019-01277-2&rft_dat=%3Cproquest_cross%3E2340044582%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2246539409&rft_id=info:pmid/31240332&rfr_iscdi=true |