Magnesium augments immunosuppressive effects of a corticosteroid in obese mice with airway inflammation

Magnesium deficiency common in obesity is known to promote chronic low-grade inflammation and aggravate asthma symptoms; however, the effects of magnesium supplementation in obese asthmatic patients have not been investigated. To examine the effects of magnesium co-administration with dexamethasone...

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Veröffentlicht in:	Asian Pacific journal of allergy and immunology 2021-03, Vol.39 (1), p.15-24
Hauptverfasser:	Moon, Jundong, Cho, Eun-Sang, Lee, Mee-Young, Son, Hwa-Young, Lee, Kyoungyoul
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Adrenal Cortex Hormones - administration & dosage Airway management Alveoli Animals Anti-Inflammatory Agents - administration & dosage Asthma Asthma - blood Asthma - drug therapy Asthma - immunology Asthma - pathology Bronchi - drug effects Bronchi - pathology Bronchoalveolar Lavage Fluid - cytology Bronchoalveolar Lavage Fluid - immunology Bronchus Cell Count Corticosteroids Cytokines - immunology Dexamethasone Dexamethasone - administration & dosage Diet, High-Fat Dietary supplements Female Goblet cells High fat diet Hypersensitivity Immunoglobulin E Immunoglobulin E - blood Immunosuppressive Agents - administration & dosage Inflammation Inflammation - blood Inflammation - drug therapy Inflammation - immunology Inflammation - pathology Interleukin 13 Lavage Magnesium Magnesium - administration & dosage Mice Mice, Inbred C57BL Obesity Obesity - blood Obesity - drug therapy Obesity - immunology Obesity - pathology Ovalbumin Respiratory tract Respiratory tract diseases Rodents Smooth muscle
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