Azomethine ylide cycloaddition: a versatile tool for preparing novel pyrrolizidino-spiro-oxindolo hybrids of the doubly conjugated alkamide piperine

A facile, multicomponent (MCR) atom-economic synthesis of novel spiro-oxindolo pyrrolizidine adducts of piperine has been achieved via an intermolecular 1,3-dipolar azomethine ylide cycloaddition reaction. Either of the two conjugated double bonds in piperine takes part in the reaction to produce tw...

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Veröffentlicht in:	Molecular diversity 2020-08, Vol.24 (3), p.627-639
Hauptverfasser:	Singh, Meenakshi, Amrutha Krishnan, A. V., Mandal, Ramkrishna, Samanta, Jayanta, Ravichandiran, V., Natarajan, Ramalingam, Bharitkar, Yogesh P., Hazra, Abhijit
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids - chemistry Azo Compounds - chemistry Benzodioxoles - chemistry Biochemistry Biomedical and Life Sciences Crystallography Cycloaddition Reaction Hybrids Life Sciences Liquid chromatography Models, Molecular Molecular Conformation Organic Chemistry Original Article Oxindoles - chemical synthesis Oxindoles - chemistry Pharmacy Piperidines - chemistry Polymer Sciences Polyunsaturated Alkamides - chemistry Pyrroles - chemistry Spectral analysis Spiro Compounds - chemistry Stereoisomerism Thiosemicarbazones - chemistry
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