H2S mediates increased interleukin (IL)-1β and IL-18 production in leukocytes from patients with periodontitis

Background: The mechanisms involved in the interplay between the bacteria and the host cells in periodontitis are not fully understood. Aim: To investigate the effect of the bacterial metabolite H 2 S on the pro-inflammatory cytokines interleukin (IL)-1β and IL-18 from periodontitis patients and hea...

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Veröffentlicht in:	Journal of oral microbiology 2019-01, Vol.11 (1), p.1617015-1617015
Hauptverfasser:	Basic, Amina, Serino, Giovanni, Leonhardt, Åsa, Dahlén, Gunnar
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria bismuth plaque test Composition Cytokines Gingiva Gum disease h2s Hydrogen sulfide IL-18 IL-1β Inflammation Inflammatory response Interleukin 18 Leukocytes Leukocytes (mononuclear) Metabolites Microbiota Odontologi Odontology Original PBMCs Periodontal disease Periodontitis Peripheral blood mononuclear cells Production methods qPCR
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