Evidence of Low-Level Dengue Virus Circulation in the South Region of Cameroon in 2018

Dengue fever is an understudied disease in many parts of Africa and little is known about its prevalence in Cameroon. We tested blood from 629 individuals from the South Region of Cameroon, collected over the course of one year, for flavivirus RNA using conventional broad range PCR. Flavivirus RNA c...

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Veröffentlicht in:Vector borne and zoonotic diseases (Larchmont, N.Y.) N.Y.), 2020-04, Vol.20 (4), p.314-317
Hauptverfasser: Mouiche, Moctar M M, Ntumvi, Nkom F, Maptue, Victorine T, Tamoufe, Ubald, Albert, Bisse, Ngum Ndze, Valantine, Nwobegahay, Julius, Gillis, Amethyst, LeBreton, Matthew, McIver, David J, Ayukekbong, James A, Saylors, Karen, Rubin, Edward M, Lange, Christian E
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container_end_page 317
container_issue 4
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container_title Vector borne and zoonotic diseases (Larchmont, N.Y.)
container_volume 20
creator Mouiche, Moctar M M
Ntumvi, Nkom F
Maptue, Victorine T
Tamoufe, Ubald
Albert, Bisse
Ngum Ndze, Valantine
Nwobegahay, Julius
Gillis, Amethyst
LeBreton, Matthew
McIver, David J
Ayukekbong, James A
Saylors, Karen
Rubin, Edward M
Lange, Christian E
description Dengue fever is an understudied disease in many parts of Africa and little is known about its prevalence in Cameroon. We tested blood from 629 individuals from the South Region of Cameroon, collected over the course of one year, for flavivirus RNA using conventional broad range PCR. Flavivirus RNA corresponding to dengue virus (DENV) serotype 1 was identified in two individuals who were also diagnosed with malaria. This finding confirms previous reports that indicate the presence of low-level circulation of DENV in Cameroon and supports the concern that dengue fever may be underdiagnosed due to more prevalent diseases that have similar symptomology and insufficient diagnostic capacity.
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subjects Adolescent
Adult
Cameroon - epidemiology
Dengue - blood
Dengue - epidemiology
Dengue - transmission
Dengue fever
Dengue Virus - genetics
Dengue Virus - isolation & purification
Diagnostic systems
Female
Fever
Humans
Malaria
Male
Polymerase Chain Reaction
Prevalence
Ribonucleic acid
Risk Factors
RNA
RNA viruses
RNA, Viral - isolation & purification
Short Communications
Symptomology
Tropical diseases
Vector-borne diseases
Viral diseases
Viruses
Young Adult
title Evidence of Low-Level Dengue Virus Circulation in the South Region of Cameroon in 2018
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