Evidence of Low-Level Dengue Virus Circulation in the South Region of Cameroon in 2018
Dengue fever is an understudied disease in many parts of Africa and little is known about its prevalence in Cameroon. We tested blood from 629 individuals from the South Region of Cameroon, collected over the course of one year, for flavivirus RNA using conventional broad range PCR. Flavivirus RNA c...
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Veröffentlicht in: | Vector borne and zoonotic diseases (Larchmont, N.Y.) N.Y.), 2020-04, Vol.20 (4), p.314-317 |
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creator | Mouiche, Moctar M M Ntumvi, Nkom F Maptue, Victorine T Tamoufe, Ubald Albert, Bisse Ngum Ndze, Valantine Nwobegahay, Julius Gillis, Amethyst LeBreton, Matthew McIver, David J Ayukekbong, James A Saylors, Karen Rubin, Edward M Lange, Christian E |
description | Dengue fever is an understudied disease in many parts of Africa and little is known about its prevalence in Cameroon. We tested blood from 629 individuals from the South Region of Cameroon, collected over the course of one year, for flavivirus RNA using conventional broad range PCR. Flavivirus RNA corresponding to dengue virus (DENV) serotype 1 was identified in two individuals who were also diagnosed with malaria. This finding confirms previous reports that indicate the presence of low-level circulation of DENV in Cameroon and supports the concern that dengue fever may be underdiagnosed due to more prevalent diseases that have similar symptomology and insufficient diagnostic capacity. |
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We tested blood from 629 individuals from the South Region of Cameroon, collected over the course of one year, for flavivirus RNA using conventional broad range PCR. Flavivirus RNA corresponding to dengue virus (DENV) serotype 1 was identified in two individuals who were also diagnosed with malaria. This finding confirms previous reports that indicate the presence of low-level circulation of DENV in Cameroon and supports the concern that dengue fever may be underdiagnosed due to more prevalent diseases that have similar symptomology and insufficient diagnostic capacity.</description><identifier>ISSN: 1530-3667</identifier><identifier>EISSN: 1557-7759</identifier><identifier>DOI: 10.1089/vbz.2019.2531</identifier><identifier>PMID: 31934826</identifier><language>eng</language><publisher>United States: Mary Ann Liebert, Inc., publishers</publisher><subject>Adolescent ; Adult ; Cameroon - epidemiology ; Dengue - blood ; Dengue - epidemiology ; Dengue - transmission ; Dengue fever ; Dengue Virus - genetics ; Dengue Virus - isolation & purification ; Diagnostic systems ; Female ; Fever ; Humans ; Malaria ; Male ; Polymerase Chain Reaction ; Prevalence ; Ribonucleic acid ; Risk Factors ; RNA ; RNA viruses ; RNA, Viral - isolation & purification ; Short Communications ; Symptomology ; Tropical diseases ; Vector-borne diseases ; Viral diseases ; Viruses ; Young Adult</subject><ispartof>Vector borne and zoonotic diseases (Larchmont, N.Y.), 2020-04, Vol.20 (4), p.314-317</ispartof><rights>2020, Mary Ann Liebert, Inc., publishers</rights><rights>Copyright Mary Ann Liebert, Inc. Apr 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c365t-3d3db715720be98a7302c6674ba81043629b5462bae16dc7b4b58334d084428f3</citedby><cites>FETCH-LOGICAL-c365t-3d3db715720be98a7302c6674ba81043629b5462bae16dc7b4b58334d084428f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31934826$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mouiche, Moctar M M</creatorcontrib><creatorcontrib>Ntumvi, Nkom F</creatorcontrib><creatorcontrib>Maptue, Victorine T</creatorcontrib><creatorcontrib>Tamoufe, Ubald</creatorcontrib><creatorcontrib>Albert, Bisse</creatorcontrib><creatorcontrib>Ngum Ndze, Valantine</creatorcontrib><creatorcontrib>Nwobegahay, Julius</creatorcontrib><creatorcontrib>Gillis, Amethyst</creatorcontrib><creatorcontrib>LeBreton, Matthew</creatorcontrib><creatorcontrib>McIver, David J</creatorcontrib><creatorcontrib>Ayukekbong, James A</creatorcontrib><creatorcontrib>Saylors, Karen</creatorcontrib><creatorcontrib>Rubin, Edward M</creatorcontrib><creatorcontrib>Lange, Christian E</creatorcontrib><title>Evidence of Low-Level Dengue Virus Circulation in the South Region of Cameroon in 2018</title><title>Vector borne and zoonotic diseases (Larchmont, N.Y.)</title><addtitle>Vector Borne Zoonotic Dis</addtitle><description>Dengue fever is an understudied disease in many parts of Africa and little is known about its prevalence in Cameroon. We tested blood from 629 individuals from the South Region of Cameroon, collected over the course of one year, for flavivirus RNA using conventional broad range PCR. Flavivirus RNA corresponding to dengue virus (DENV) serotype 1 was identified in two individuals who were also diagnosed with malaria. This finding confirms previous reports that indicate the presence of low-level circulation of DENV in Cameroon and supports the concern that dengue fever may be underdiagnosed due to more prevalent diseases that have similar symptomology and insufficient diagnostic capacity.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Cameroon - epidemiology</subject><subject>Dengue - blood</subject><subject>Dengue - epidemiology</subject><subject>Dengue - transmission</subject><subject>Dengue fever</subject><subject>Dengue Virus - genetics</subject><subject>Dengue Virus - isolation & purification</subject><subject>Diagnostic systems</subject><subject>Female</subject><subject>Fever</subject><subject>Humans</subject><subject>Malaria</subject><subject>Male</subject><subject>Polymerase Chain Reaction</subject><subject>Prevalence</subject><subject>Ribonucleic acid</subject><subject>Risk Factors</subject><subject>RNA</subject><subject>RNA viruses</subject><subject>RNA, Viral - isolation & purification</subject><subject>Short Communications</subject><subject>Symptomology</subject><subject>Tropical diseases</subject><subject>Vector-borne diseases</subject><subject>Viral diseases</subject><subject>Viruses</subject><subject>Young Adult</subject><issn>1530-3667</issn><issn>1557-7759</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDtv2zAURomgQZ1Hx6wFgS5d5JC8fGks3DQpYCBAXqtAStexDFl0SclF8-tDwWmHLpkucXnuhw-HkAvO5pzZ8nLvX-aC8XIuFPAjcsKVMoUxqvwwvYEVoLWZkdOUNowJbrn6SGbAS5BW6BPydLVvG-xrpGFFl-F3scQ9dvQ79s8j0qc2joku2liPnRva0NO2p8Ma6X0YhzW9w-dply8XbosxHP5zG3tOjleuS_jpbZ6Rxx9XD4ubYnl7_XPxbVnUoNVQQAONN1wZwTyW1hlgos59pXeWMwlalF5JLbxDrpvaeOmVBZANs1IKu4Iz8vWQu4vh14hpqLZtqrHrXI9hTJUAsEwzZXRGv_yHbsIY-9wuU1ZaC1bITBUHqo4hpYirahfbrYt_Ks6qSXiVhVeT8GoSnvnPb6mj32Lzj_5rOANwAKa16_uuRY9xeCf2FfC2iZo</recordid><startdate>20200401</startdate><enddate>20200401</enddate><creator>Mouiche, Moctar M M</creator><creator>Ntumvi, Nkom F</creator><creator>Maptue, Victorine T</creator><creator>Tamoufe, Ubald</creator><creator>Albert, Bisse</creator><creator>Ngum Ndze, Valantine</creator><creator>Nwobegahay, Julius</creator><creator>Gillis, Amethyst</creator><creator>LeBreton, Matthew</creator><creator>McIver, David J</creator><creator>Ayukekbong, James A</creator><creator>Saylors, Karen</creator><creator>Rubin, Edward M</creator><creator>Lange, Christian E</creator><general>Mary Ann Liebert, Inc., publishers</general><general>Mary Ann Liebert, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7SS</scope><scope>7U9</scope><scope>C1K</scope><scope>H94</scope><scope>M7N</scope><scope>7X8</scope></search><sort><creationdate>20200401</creationdate><title>Evidence of Low-Level Dengue Virus Circulation in the South Region of Cameroon in 2018</title><author>Mouiche, Moctar M M ; 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subjects | Adolescent Adult Cameroon - epidemiology Dengue - blood Dengue - epidemiology Dengue - transmission Dengue fever Dengue Virus - genetics Dengue Virus - isolation & purification Diagnostic systems Female Fever Humans Malaria Male Polymerase Chain Reaction Prevalence Ribonucleic acid Risk Factors RNA RNA viruses RNA, Viral - isolation & purification Short Communications Symptomology Tropical diseases Vector-borne diseases Viral diseases Viruses Young Adult |
title | Evidence of Low-Level Dengue Virus Circulation in the South Region of Cameroon in 2018 |
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