Efficacy, rate of tumor response, and safety of a short course (12-24 weeks) of oral vismodegib in various histologic subtypes (infiltrative, nodular, and superficial) of high-risk or locally advanced basal cell carcinoma, in an open-label, prospective case series clinical trial

Vismodegib demonstrated 60% response rates in the ERIVANCE trial. Basal cell carcinoma has various histopathologies. Their effect on response is unclear. The purpose of this study was to determine whether basal cell carcinoma histopathology affected vismodegib response. This phase 2b, single-center,...

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Veröffentlicht in:Journal of the American Academy of Dermatology 2020-04, Vol.82 (4), p.946-954
Hauptverfasser: Fosko, Scott W., Chu, Melinda B., Armbrecht, Eric, Galperin, Tim, Potts, Geoffrey A., Mattox, Adam, Kurta, Anastasia, Polito, Kristen, Slutsky, Jordan B., Burkemper, Nicole M., Hurley, M. Yadira
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Sprache:eng
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