Comparison of hemodynamics, cardiac electrophysiology, and ventricular arrhythmia in an open- and a closed-chest porcine model of acute myocardial infarction

Ventricular fibrillation (VF) during acute myocardial infarction (AMI) is an important contributor to sudden cardiac death. Large animal models are widely used to study AMI-induced arrhythmia, but the mode of AMI induction ranges from thoracotomy and surgical ligation of a coronary vessel (open ches...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2020-02, Vol.318 (2), p.H391-H400
Hauptverfasser:	Lubberding, Anniek F, Sattler, Stefan M, Flethøj, Mette, Tfelt-Hansen, Jacob, Jespersen, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - physiology Animals Arrhythmias, Cardiac - physiopathology Coronary Vessels - physiopathology Disease Models, Animal Electrocardiography Electrophysiologic Techniques, Cardiac Female Heart - physiopathology Hemodynamics Myocardial Contraction Myocardial Infarction - physiopathology Swine Tachycardia, Ventricular - physiopathology Ventricular Premature Complexes - physiopathology
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