Survival rates and risk factors for failure using an interposition vein graft for fingertip amputations with segmental vessel defects

Purpose This study aimed to compare survival rates and risk factors of replantation failures using an interposition vein graft in fingertip amputations with segmental vessel defects with those using simple end‐to‐end anastomosis in amputations. Patients and methods Between 2004 and 2015, 776 (647 ma...

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Veröffentlicht in:Microsurgery 2020-05, Vol.40 (4), p.447-451
Hauptverfasser: Kwon, Yu‐Jun, Jung, Hyoung‐Seok, Ahn, Byung‐Moon, Lee, Jae‐Sung, Park, Hyeong‐Jun, Ha, Yong‐Chan
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container_end_page 451
container_issue 4
container_start_page 447
container_title Microsurgery
container_volume 40
creator Kwon, Yu‐Jun
Jung, Hyoung‐Seok
Ahn, Byung‐Moon
Lee, Jae‐Sung
Park, Hyeong‐Jun
Ha, Yong‐Chan
description Purpose This study aimed to compare survival rates and risk factors of replantation failures using an interposition vein graft in fingertip amputations with segmental vessel defects with those using simple end‐to‐end anastomosis in amputations. Patients and methods Between 2004 and 2015, 776 (647 males and 129 females) with single Zone I or II amputations of digits underwent replantation. Among these, simple end‐to‐end anastomosis was performed in 698 replantations, while interposition vein grafts were used for either arterial or venous repair or both in 78 amputated fingertips. The survival rate was compared between the groups. Logistic regression analysis was performed to identify risk factors predicting replantation failure in all study subjects. Results Among 776 replantations, 713 (91.9%) survived. At latest follow‐up, of 698 cases in the simple anastomosis group, 650 (93.1%) survived; of 78 cases in the vein graft group, 63 (80.8%) survived (p > .001). Logistic regression analysis revealed that avulsion type (odds ratio [OR] 3.121; 95% confidence interval [CI], 1.211–8.064; p = .018) and zone II amputation (OR, 2.370; 95% CI, 1.382–4.065; p = .002) were significant risk factors for replantation failure. Conclusion This study demonstrates that the survival rate (80.8%) of the vein graft in fingertip amputation with segmental vessel defects was shown to be a possible option to increase the survival rates in case with segmental vessel defects where simple anastomosis could not be performed. However, avulsion type and zone II amputation are important risk factors of replantation failures.
doi_str_mv 10.1002/micr.30554
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Patients and methods Between 2004 and 2015, 776 (647 males and 129 females) with single Zone I or II amputations of digits underwent replantation. Among these, simple end‐to‐end anastomosis was performed in 698 replantations, while interposition vein grafts were used for either arterial or venous repair or both in 78 amputated fingertips. The survival rate was compared between the groups. Logistic regression analysis was performed to identify risk factors predicting replantation failure in all study subjects. Results Among 776 replantations, 713 (91.9%) survived. At latest follow‐up, of 698 cases in the simple anastomosis group, 650 (93.1%) survived; of 78 cases in the vein graft group, 63 (80.8%) survived (p &gt; .001). Logistic regression analysis revealed that avulsion type (odds ratio [OR] 3.121; 95% confidence interval [CI], 1.211–8.064; p = .018) and zone II amputation (OR, 2.370; 95% CI, 1.382–4.065; p = .002) were significant risk factors for replantation failure. Conclusion This study demonstrates that the survival rate (80.8%) of the vein graft in fingertip amputation with segmental vessel defects was shown to be a possible option to increase the survival rates in case with segmental vessel defects where simple anastomosis could not be performed. However, avulsion type and zone II amputation are important risk factors of replantation failures.</description><identifier>ISSN: 0738-1085</identifier><identifier>EISSN: 1098-2752</identifier><identifier>DOI: 10.1002/micr.30554</identifier><identifier>PMID: 31926042</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley &amp; Sons, Inc</publisher><subject>Adolescent ; Adult ; Aged ; Amputation ; Amputation, Traumatic - surgery ; Anastomosis ; Blood vessels ; Confidence intervals ; Defects ; Failure ; Failure analysis ; Female ; Finger Injuries - surgery ; Graft Survival ; Grafting ; Humans ; Male ; Middle Aged ; Regression analysis ; Replantation - methods ; Retrospective Studies ; Risk analysis ; Risk factors ; Statistical analysis ; Survival ; Veins ; Veins &amp; arteries ; Veins - transplantation ; Young Adult</subject><ispartof>Microsurgery, 2020-05, Vol.40 (4), p.447-451</ispartof><rights>2020 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3574-7c234a4ca4b72e35a2e7fc5218991ce89d007ad63d61f3e06bdb6dccea99a8233</citedby><cites>FETCH-LOGICAL-c3574-7c234a4ca4b72e35a2e7fc5218991ce89d007ad63d61f3e06bdb6dccea99a8233</cites><orcidid>0000-0002-6249-0581</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fmicr.30554$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fmicr.30554$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31926042$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kwon, Yu‐Jun</creatorcontrib><creatorcontrib>Jung, Hyoung‐Seok</creatorcontrib><creatorcontrib>Ahn, Byung‐Moon</creatorcontrib><creatorcontrib>Lee, Jae‐Sung</creatorcontrib><creatorcontrib>Park, Hyeong‐Jun</creatorcontrib><creatorcontrib>Ha, Yong‐Chan</creatorcontrib><title>Survival rates and risk factors for failure using an interposition vein graft for fingertip amputations with segmental vessel defects</title><title>Microsurgery</title><addtitle>Microsurgery</addtitle><description>Purpose This study aimed to compare survival rates and risk factors of replantation failures using an interposition vein graft in fingertip amputations with segmental vessel defects with those using simple end‐to‐end anastomosis in amputations. Patients and methods Between 2004 and 2015, 776 (647 males and 129 females) with single Zone I or II amputations of digits underwent replantation. Among these, simple end‐to‐end anastomosis was performed in 698 replantations, while interposition vein grafts were used for either arterial or venous repair or both in 78 amputated fingertips. The survival rate was compared between the groups. Logistic regression analysis was performed to identify risk factors predicting replantation failure in all study subjects. Results Among 776 replantations, 713 (91.9%) survived. At latest follow‐up, of 698 cases in the simple anastomosis group, 650 (93.1%) survived; of 78 cases in the vein graft group, 63 (80.8%) survived (p &gt; .001). Logistic regression analysis revealed that avulsion type (odds ratio [OR] 3.121; 95% confidence interval [CI], 1.211–8.064; p = .018) and zone II amputation (OR, 2.370; 95% CI, 1.382–4.065; p = .002) were significant risk factors for replantation failure. Conclusion This study demonstrates that the survival rate (80.8%) of the vein graft in fingertip amputation with segmental vessel defects was shown to be a possible option to increase the survival rates in case with segmental vessel defects where simple anastomosis could not be performed. However, avulsion type and zone II amputation are important risk factors of replantation failures.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Amputation</subject><subject>Amputation, Traumatic - surgery</subject><subject>Anastomosis</subject><subject>Blood vessels</subject><subject>Confidence intervals</subject><subject>Defects</subject><subject>Failure</subject><subject>Failure analysis</subject><subject>Female</subject><subject>Finger Injuries - surgery</subject><subject>Graft Survival</subject><subject>Grafting</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Regression analysis</subject><subject>Replantation - methods</subject><subject>Retrospective Studies</subject><subject>Risk analysis</subject><subject>Risk factors</subject><subject>Statistical analysis</subject><subject>Survival</subject><subject>Veins</subject><subject>Veins &amp; arteries</subject><subject>Veins - transplantation</subject><subject>Young Adult</subject><issn>0738-1085</issn><issn>1098-2752</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp90ctOGzEUBmCrKioh7aYPgCx1g5Am-DI3L6uItkhBSLRdW47nTHCYGz6eoDwA743TARYsuvJZfPrPkX9CvnK24IyJi9ZZv5Asy9IPZMaZKhNRZOIjmbFClglnZXZMThC3jDGlCvWJHEuuRM5SMSNPv0e_czvTUG8CIDVdRb3De1obG3qPtO59nF0zeqAjum4TCXVdAD_06ILrO7oD19GNN3WYdETggxuoaYcxmINB-ujCHUXYtNCFuG0HiNDQCmqwAT-To9o0CF9e3jn5--Pyz_JXsrr5ebX8vkqszIo0KayQqUmtSdeFAJkZAUVtM8FLpbiFUlWMFabKZZXzWgLL19U6r6wFo5QphZRzcjblDr5_GAGDbh1aaBrTQT-ijiQXaVx1oN_e0W0_-i5ep0XKuBTxb7OozidlfY_oodaDd63xe82ZPpSjD-Xof-VEfPoSOa5bqN7oaxsR8Ak8ugb2_4nS11fL2yn0GYgJnKc</recordid><startdate>202005</startdate><enddate>202005</enddate><creator>Kwon, Yu‐Jun</creator><creator>Jung, Hyoung‐Seok</creator><creator>Ahn, Byung‐Moon</creator><creator>Lee, Jae‐Sung</creator><creator>Park, Hyeong‐Jun</creator><creator>Ha, Yong‐Chan</creator><general>John Wiley &amp; 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arteries</topic><topic>Veins - transplantation</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kwon, Yu‐Jun</creatorcontrib><creatorcontrib>Jung, Hyoung‐Seok</creatorcontrib><creatorcontrib>Ahn, Byung‐Moon</creatorcontrib><creatorcontrib>Lee, Jae‐Sung</creatorcontrib><creatorcontrib>Park, Hyeong‐Jun</creatorcontrib><creatorcontrib>Ha, Yong‐Chan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Microsurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kwon, Yu‐Jun</au><au>Jung, Hyoung‐Seok</au><au>Ahn, Byung‐Moon</au><au>Lee, Jae‐Sung</au><au>Park, Hyeong‐Jun</au><au>Ha, Yong‐Chan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Survival rates and risk factors for failure using an interposition vein graft for fingertip amputations with segmental vessel defects</atitle><jtitle>Microsurgery</jtitle><addtitle>Microsurgery</addtitle><date>2020-05</date><risdate>2020</risdate><volume>40</volume><issue>4</issue><spage>447</spage><epage>451</epage><pages>447-451</pages><issn>0738-1085</issn><eissn>1098-2752</eissn><abstract>Purpose This study aimed to compare survival rates and risk factors of replantation failures using an interposition vein graft in fingertip amputations with segmental vessel defects with those using simple end‐to‐end anastomosis in amputations. Patients and methods Between 2004 and 2015, 776 (647 males and 129 females) with single Zone I or II amputations of digits underwent replantation. Among these, simple end‐to‐end anastomosis was performed in 698 replantations, while interposition vein grafts were used for either arterial or venous repair or both in 78 amputated fingertips. The survival rate was compared between the groups. Logistic regression analysis was performed to identify risk factors predicting replantation failure in all study subjects. Results Among 776 replantations, 713 (91.9%) survived. At latest follow‐up, of 698 cases in the simple anastomosis group, 650 (93.1%) survived; of 78 cases in the vein graft group, 63 (80.8%) survived (p &gt; .001). Logistic regression analysis revealed that avulsion type (odds ratio [OR] 3.121; 95% confidence interval [CI], 1.211–8.064; p = .018) and zone II amputation (OR, 2.370; 95% CI, 1.382–4.065; p = .002) were significant risk factors for replantation failure. Conclusion This study demonstrates that the survival rate (80.8%) of the vein graft in fingertip amputation with segmental vessel defects was shown to be a possible option to increase the survival rates in case with segmental vessel defects where simple anastomosis could not be performed. However, avulsion type and zone II amputation are important risk factors of replantation failures.</abstract><cop>Hoboken, USA</cop><pub>John Wiley &amp; Sons, Inc</pub><pmid>31926042</pmid><doi>10.1002/micr.30554</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-6249-0581</orcidid></addata></record>
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subjects Adolescent
Adult
Aged
Amputation
Amputation, Traumatic - surgery
Anastomosis
Blood vessels
Confidence intervals
Defects
Failure
Failure analysis
Female
Finger Injuries - surgery
Graft Survival
Grafting
Humans
Male
Middle Aged
Regression analysis
Replantation - methods
Retrospective Studies
Risk analysis
Risk factors
Statistical analysis
Survival
Veins
Veins & arteries
Veins - transplantation
Young Adult
title Survival rates and risk factors for failure using an interposition vein graft for fingertip amputations with segmental vessel defects
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