Downregulation of microRNA‐135b promotes atherosclerotic plaque stabilization in atherosclerotic mice by upregulating erythropoietin receptor

Atherosclerotic plaque rupture is an important pathophysiologic mechanism of acute coronary syndrome. Emerging microRNAs (miRNAs) have been implicated in the atherosclerotic plaque formation and macrophage autophagy during the development of atherosclerosis (AS). Hence, this study was conducted to e...

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Veröffentlicht in:	IUBMB life 2020-02, Vol.72 (2), p.198-213
Hauptverfasser:	Wu, Bo‐Wen, Liu, Yu, Wu, Mi‐Shan, Meng, Yun‐Hui, Lu, Meng, Guo, Jin‐Dong, Zhou, Yu‐Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase AKT protein Animal models Aorta Apoptosis Arteriosclerosis Atherosclerosis Autophagy Butter Cell proliferation Erythropoietin erythropoietin receptor Inflammation Macrophages MicroRNAs microRNA‐135b miRNA Phagocytosis PI3K/Akt signaling pathway Signal transduction
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