Cord blood metabolic markers are strong mediators of the effect of maternal adiposity on fetal growth in pregnancies across the glucose tolerance spectrum: the PANDORA study

Aims/hypothesis We aimed to assess associations between cord blood metabolic markers and fetal overgrowth, and whether cord markers mediated the impact of maternal adiposity on neonatal anthropometric outcomes among children born to Indigenous and Non-Indigenous Australian women with normal glucose...

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Veröffentlicht in:	Diabetologia 2020-03, Vol.63 (3), p.497-507
Hauptverfasser:	Lee, I-Lynn, Barr, Elizabeth L. M., Longmore, Danielle, Barzi, Federica, Brown, Alex D. H., Connors, Christine, Boyle, Jacqueline A., Kirkwood, Marie, Hampton, Vanya, Lynch, Michael, Lu, Zhong X., O’Dea, Kerin, Oats, Jeremy, McIntyre, H. David, Zimmet, Paul, Shaw, Jonathan E., Maple-Brown, Louise J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Adiposity - physiology Adult Australia - epidemiology Biomarkers - analysis Biomarkers - metabolism Birth weight Birth Weight - physiology Body fat Body Mass Index C-reactive protein Cholesterol Cohort Studies Cord blood Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - metabolism Diabetes, Gestational - diagnosis Diabetes, Gestational - epidemiology Diabetes, Gestational - metabolism Female Fetal Blood - metabolism Fetal Development - physiology Fetuses Gestational age Gestational diabetes Glucose Glucose - metabolism Glucose Intolerance - diagnosis Glucose Intolerance - epidemiology Glucose Intolerance - metabolism Glucose tolerance Health risk assessment High density lipoprotein Human Physiology Humans Hyperglycemia - diagnosis Hyperglycemia - epidemiology Hyperglycemia - metabolism Infant, Newborn Internal Medicine Male Medicine Medicine & Public Health Metabolic Diseases Metabolism Neonates Newborn babies Obesity - complications Obesity - diagnosis Obesity - epidemiology Obesity - metabolism Peptides Pregnancy Pregnancy Complications - diagnosis Pregnancy Complications - epidemiology Pregnancy Complications - metabolism Pregnancy in Diabetics - diagnosis Pregnancy in Diabetics - epidemiology Pregnancy in Diabetics - metabolism Pregnancy Outcome - epidemiology Prognosis Skinfold thickness Young Adult
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