Loss of H3K27 trimethylation by immunohistochemistry is frequent in oligodendroglioma, IDH-mutant and 1p/19q-codeleted, but is neither a sensitive nor a specific marker

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Bibliographische Detailangaben
Veröffentlicht in:	Acta neuropathologica 2020-03, Vol.139 (3), p.597-600
Hauptverfasser:	Pekmezci, Melike, Phillips, Joanna J., Dirilenoglu, Fikret, Atasever-Rezanko, Turkan, Tihan, Tarik, Solomon, David, Bollen, Andrew, Perry, Arie
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biomarkers, Tumor - analysis Biomarkers, Tumor - genetics Brain Neoplasms - diagnosis Brain Neoplasms - genetics Chromosomes, Human, Pair 1 - genetics Chromosomes, Human, Pair 19 - genetics Correspondence DNA Methylation Female Histones - analysis Histones - genetics Humans Immunohistochemistry Isocitrate Dehydrogenase - genetics Male Medicine Medicine & Public Health Methylation Neurosciences Oligodendroglioma Oligodendroglioma - diagnosis Oligodendroglioma - genetics Pathology Sensitivity and Specificity
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