Loss of H3K27 trimethylation by immunohistochemistry is frequent in oligodendroglioma, IDH-mutant and 1p/19q-codeleted, but is neither a sensitive nor a specific marker
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Veröffentlicht in: | Acta neuropathologica 2020-03, Vol.139 (3), p.597-600 |
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container_title | Acta neuropathologica |
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creator | Pekmezci, Melike Phillips, Joanna J. Dirilenoglu, Fikret Atasever-Rezanko, Turkan Tihan, Tarik Solomon, David Bollen, Andrew Perry, Arie |
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doi_str_mv | 10.1007/s00401-019-02123-8 |
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analysis</topic><topic>Biomarkers, Tumor - genetics</topic><topic>Brain Neoplasms - diagnosis</topic><topic>Brain Neoplasms - genetics</topic><topic>Chromosomes, Human, Pair 1 - genetics</topic><topic>Chromosomes, Human, Pair 19 - genetics</topic><topic>Clinical Neurology</topic><topic>Correspondence</topic><topic>DNA Methylation</topic><topic>Female</topic><topic>Histones - analysis</topic><topic>Histones - genetics</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Isocitrate Dehydrogenase - genetics</topic><topic>Life Sciences & Biomedicine</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Methylation</topic><topic>Neurosciences</topic><topic>Neurosciences & Neurology</topic><topic>Oligodendroglioma</topic><topic>Oligodendroglioma - diagnosis</topic><topic>Oligodendroglioma - genetics</topic><topic>Pathology</topic><topic>Science & Technology</topic><topic>Sensitivity and Specificity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pekmezci, Melike</creatorcontrib><creatorcontrib>Phillips, Joanna J.</creatorcontrib><creatorcontrib>Dirilenoglu, Fikret</creatorcontrib><creatorcontrib>Atasever-Rezanko, Turkan</creatorcontrib><creatorcontrib>Tihan, Tarik</creatorcontrib><creatorcontrib>Solomon, David</creatorcontrib><creatorcontrib>Bollen, Andrew</creatorcontrib><creatorcontrib>Perry, Arie</creatorcontrib><collection>Web of Science - 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subjects | Adult Biomarkers, Tumor - analysis Biomarkers, Tumor - genetics Brain Neoplasms - diagnosis Brain Neoplasms - genetics Chromosomes, Human, Pair 1 - genetics Chromosomes, Human, Pair 19 - genetics Clinical Neurology Correspondence DNA Methylation Female Histones - analysis Histones - genetics Humans Immunohistochemistry Isocitrate Dehydrogenase - genetics Life Sciences & Biomedicine Male Medicine Medicine & Public Health Methylation Neurosciences Neurosciences & Neurology Oligodendroglioma Oligodendroglioma - diagnosis Oligodendroglioma - genetics Pathology Science & Technology Sensitivity and Specificity |
title | Loss of H3K27 trimethylation by immunohistochemistry is frequent in oligodendroglioma, IDH-mutant and 1p/19q-codeleted, but is neither a sensitive nor a specific marker |
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