Loss of H3K27 trimethylation by immunohistochemistry is frequent in oligodendroglioma, IDH-mutant and 1p/19q-codeleted, but is neither a sensitive nor a specific marker

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Veröffentlicht in:Acta neuropathologica 2020-03, Vol.139 (3), p.597-600
Hauptverfasser: Pekmezci, Melike, Phillips, Joanna J., Dirilenoglu, Fikret, Atasever-Rezanko, Turkan, Tihan, Tarik, Solomon, David, Bollen, Andrew, Perry, Arie
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container_title Acta neuropathologica
container_volume 139
creator Pekmezci, Melike
Phillips, Joanna J.
Dirilenoglu, Fikret
Atasever-Rezanko, Turkan
Tihan, Tarik
Solomon, David
Bollen, Andrew
Perry, Arie
description
doi_str_mv 10.1007/s00401-019-02123-8
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subjects Adult
Biomarkers, Tumor - analysis
Biomarkers, Tumor - genetics
Brain Neoplasms - diagnosis
Brain Neoplasms - genetics
Chromosomes, Human, Pair 1 - genetics
Chromosomes, Human, Pair 19 - genetics
Clinical Neurology
Correspondence
DNA Methylation
Female
Histones - analysis
Histones - genetics
Humans
Immunohistochemistry
Isocitrate Dehydrogenase - genetics
Life Sciences & Biomedicine
Male
Medicine
Medicine & Public Health
Methylation
Neurosciences
Neurosciences & Neurology
Oligodendroglioma
Oligodendroglioma - diagnosis
Oligodendroglioma - genetics
Pathology
Science & Technology
Sensitivity and Specificity
title Loss of H3K27 trimethylation by immunohistochemistry is frequent in oligodendroglioma, IDH-mutant and 1p/19q-codeleted, but is neither a sensitive nor a specific marker
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