Sexual dimorphism in the microbiology of the CF ‘Gender Gap’: Estrogen modulation of Pseudomonas aeruginosa virulence

[Display omitted] There is increasing evidence for sexual dimorphism of estrogen (E2) actions in the exacerbation of lung function, infection and inflammation in females with cystic fibrosis - the so-called “CF gender gap”. The effects of estrogen on virulence factors that enhance P. aeruginosa pers...

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Veröffentlicht in:	Steroids 2020-04, Vol.156, p.108575-108575, Article 108575
Hauptverfasser:	Tyrrell, Jean, Harvey, Brian J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cells, Cultured CF gender gap Child, Preschool Cystic Fibrosis - metabolism Cystic Fibrosis - microbiology Estrogen Estrogens - metabolism Female Humans Male PsA virulence Pseudomonas aeruginosa Pseudomonas aeruginosa - isolation & purification Pseudomonas aeruginosa - metabolism Pseudomonas aeruginosa - pathogenicity Sex Characteristics Sexual dimorphism in CF Virulence
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