Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice
γ-Aminobutyric acid (GABA) uptake transporters are membrane transport proteins that are involved in the pathophysiology of a number of neurological disorders. Some types of chronic pain appear to result from the dysfunction of the GABAergic system. The deficiency of mouse GAT1 transporter (mGAT1) ab...
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Veröffentlicht in: | European journal of medicinal chemistry 2020-02, Vol.188, p.111920-111920, Article 111920 |
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Sprache: | eng |
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