OPTN/SRTR 2018 Annual Data Report: Liver
Data on adult liver transplants performed in the US in 2018 are notable for (1) continued growth in numbers of new waitlist registrants (11,844) and transplants performed (8250); (2) continued increase in the transplant rate (54.5 per 100 waitlist‐years); (3) a precipitous decline in waitlist regist...
Gespeichert in:
| Veröffentlicht in: | American journal of transplantation 2020-01, Vol.20 (s1), p.193-299 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 299 |
|---|---|
| container_issue | s1 |
| container_start_page | 193 |
| container_title | American journal of transplantation |
| container_volume | 20 |
| creator | Kwong, A. Kim, W. R. Lake, J. R. Smith, J. M. Schladt, D. P. Skeans, M. A. Noreen, S. M. Foutz, J. Miller, E. Snyder, J. J. Israni, A. K. Kasiske, B. L. |
| description | Data on adult liver transplants performed in the US in 2018 are notable for (1) continued growth in numbers of new waitlist registrants (11,844) and transplants performed (8250); (2) continued increase in the transplant rate (54.5 per 100 waitlist‐years); (3) a precipitous decline in waitlist registrations and transplants for hepatitis‐C‐related indications; (4) increases in waitlist registrants and recipients with alcoholic liver disease and with clinical profiles consistent with non‐alcoholic fatty liver disease; (5) increased use of hepatitis C virus antibody‐positive donor livers; and (6) continued improvement in graft survival despite changing recipient characteristics such as older age and higher rates of obesity and diabetes. Variability in transplant rates remained by candidate race, hepatocellular carcinoma status, urgency status, and geography. The volume of pediatric liver transplants was relatively unchanged. The highest rate of pre‐transplant mortality persisted for children aged younger than 1 year. Children underwent transplant at higher acuity than in the past, as evidenced by higher model for end‐stage liver disease/pediatric end‐stage liver disease scores and listings at status 1A and 1B at transplant. Despite higher illness severity scores at transplant, pediatric graft and patient survival posttransplant have improved over time. |
| doi_str_mv | 10.1111/ajt.15674 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2333605400</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2333605400</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3884-51f7ac73191e56f257b1664468a20b0823cd14a2d8ad1055ba21b6a3d071812c3</originalsourceid><addsrcrecordid>eNp10E1Lw0AQBuBFFFurB_-ABLzUQ9qd_crWW6jfFCs1npdNsoGUNKm7idJ_b9rUHgTnMnN4eBlehC4Bj6CdsV7WI-AiYEeoDwJjXwCjx4eb8h46c26JMQREklPUoyAnkgHto-H8LXodvy-ihUcwSC8sy0YX3p2utbcw68rWt94s_zL2HJ1kunDmYr8H6OPhPpo--bP54_M0nPkJlZL5HLJAJwGFCRguMsKDGIRgTEhNcIwloUkKTJNU6hQw57EmEAtNUxyABJLQARp2uWtbfTbG1WqVu8QUhS5N1ThFKKUCc4ZxS6__0GXV2LL9bqtgQiTdqZtOJbZyzppMrW2-0najAKttfaqtT-3qa-3VPrGJVyY9yN--WjDuwHdemM3_SSp8ibrIH4Tecyw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2331928300</pqid></control><display><type>article</type><title>OPTN/SRTR 2018 Annual Data Report: Liver</title><source>MEDLINE</source><source>Wiley Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>Kwong, A. ; Kim, W. R. ; Lake, J. R. ; Smith, J. M. ; Schladt, D. P. ; Skeans, M. A. ; Noreen, S. M. ; Foutz, J. ; Miller, E. ; Snyder, J. J. ; Israni, A. K. ; Kasiske, B. L.</creator><creatorcontrib>Kwong, A. ; Kim, W. R. ; Lake, J. R. ; Smith, J. M. ; Schladt, D. P. ; Skeans, M. A. ; Noreen, S. M. ; Foutz, J. ; Miller, E. ; Snyder, J. J. ; Israni, A. K. ; Kasiske, B. L.</creatorcontrib><description>Data on adult liver transplants performed in the US in 2018 are notable for (1) continued growth in numbers of new waitlist registrants (11,844) and transplants performed (8250); (2) continued increase in the transplant rate (54.5 per 100 waitlist‐years); (3) a precipitous decline in waitlist registrations and transplants for hepatitis‐C‐related indications; (4) increases in waitlist registrants and recipients with alcoholic liver disease and with clinical profiles consistent with non‐alcoholic fatty liver disease; (5) increased use of hepatitis C virus antibody‐positive donor livers; and (6) continued improvement in graft survival despite changing recipient characteristics such as older age and higher rates of obesity and diabetes. Variability in transplant rates remained by candidate race, hepatocellular carcinoma status, urgency status, and geography. The volume of pediatric liver transplants was relatively unchanged. The highest rate of pre‐transplant mortality persisted for children aged younger than 1 year. Children underwent transplant at higher acuity than in the past, as evidenced by higher model for end‐stage liver disease/pediatric end‐stage liver disease scores and listings at status 1A and 1B at transplant. Despite higher illness severity scores at transplant, pediatric graft and patient survival posttransplant have improved over time.</description><identifier>ISSN: 1600-6135</identifier><identifier>EISSN: 1600-6143</identifier><identifier>DOI: 10.1111/ajt.15674</identifier><identifier>PMID: 31898413</identifier><language>eng</language><publisher>United States: Elsevier Limited</publisher><subject>Acuity ; allocation ; Children ; Diabetes mellitus ; distribution ; Fatty liver ; Geography ; Graft Survival ; Hepatitis ; Hepatitis C ; Hepatocellular carcinoma ; Humans ; Liver diseases ; Liver transplant ; Liver transplantation ; Liver Transplantation - statistics & numerical data ; Liver transplants ; Pediatrics ; Registries ; Resource Allocation ; Survival ; Tissue and Organ Procurement - methods ; Tissue Donors - supply & distribution ; Transplants & implants ; United States ; waiting list ; Waiting Lists</subject><ispartof>American journal of transplantation, 2020-01, Vol.20 (s1), p.193-299</ispartof><rights>.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3884-51f7ac73191e56f257b1664468a20b0823cd14a2d8ad1055ba21b6a3d071812c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fajt.15674$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fajt.15674$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31898413$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kwong, A.</creatorcontrib><creatorcontrib>Kim, W. R.</creatorcontrib><creatorcontrib>Lake, J. R.</creatorcontrib><creatorcontrib>Smith, J. M.</creatorcontrib><creatorcontrib>Schladt, D. P.</creatorcontrib><creatorcontrib>Skeans, M. A.</creatorcontrib><creatorcontrib>Noreen, S. M.</creatorcontrib><creatorcontrib>Foutz, J.</creatorcontrib><creatorcontrib>Miller, E.</creatorcontrib><creatorcontrib>Snyder, J. J.</creatorcontrib><creatorcontrib>Israni, A. K.</creatorcontrib><creatorcontrib>Kasiske, B. L.</creatorcontrib><title>OPTN/SRTR 2018 Annual Data Report: Liver</title><title>American journal of transplantation</title><addtitle>Am J Transplant</addtitle><description>Data on adult liver transplants performed in the US in 2018 are notable for (1) continued growth in numbers of new waitlist registrants (11,844) and transplants performed (8250); (2) continued increase in the transplant rate (54.5 per 100 waitlist‐years); (3) a precipitous decline in waitlist registrations and transplants for hepatitis‐C‐related indications; (4) increases in waitlist registrants and recipients with alcoholic liver disease and with clinical profiles consistent with non‐alcoholic fatty liver disease; (5) increased use of hepatitis C virus antibody‐positive donor livers; and (6) continued improvement in graft survival despite changing recipient characteristics such as older age and higher rates of obesity and diabetes. Variability in transplant rates remained by candidate race, hepatocellular carcinoma status, urgency status, and geography. The volume of pediatric liver transplants was relatively unchanged. The highest rate of pre‐transplant mortality persisted for children aged younger than 1 year. Children underwent transplant at higher acuity than in the past, as evidenced by higher model for end‐stage liver disease/pediatric end‐stage liver disease scores and listings at status 1A and 1B at transplant. Despite higher illness severity scores at transplant, pediatric graft and patient survival posttransplant have improved over time.</description><subject>Acuity</subject><subject>allocation</subject><subject>Children</subject><subject>Diabetes mellitus</subject><subject>distribution</subject><subject>Fatty liver</subject><subject>Geography</subject><subject>Graft Survival</subject><subject>Hepatitis</subject><subject>Hepatitis C</subject><subject>Hepatocellular carcinoma</subject><subject>Humans</subject><subject>Liver diseases</subject><subject>Liver transplant</subject><subject>Liver transplantation</subject><subject>Liver Transplantation - statistics & numerical data</subject><subject>Liver transplants</subject><subject>Pediatrics</subject><subject>Registries</subject><subject>Resource Allocation</subject><subject>Survival</subject><subject>Tissue and Organ Procurement - methods</subject><subject>Tissue Donors - supply & distribution</subject><subject>Transplants & implants</subject><subject>United States</subject><subject>waiting list</subject><subject>Waiting Lists</subject><issn>1600-6135</issn><issn>1600-6143</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10E1Lw0AQBuBFFFurB_-ABLzUQ9qd_crWW6jfFCs1npdNsoGUNKm7idJ_b9rUHgTnMnN4eBlehC4Bj6CdsV7WI-AiYEeoDwJjXwCjx4eb8h46c26JMQREklPUoyAnkgHto-H8LXodvy-ihUcwSC8sy0YX3p2utbcw68rWt94s_zL2HJ1kunDmYr8H6OPhPpo--bP54_M0nPkJlZL5HLJAJwGFCRguMsKDGIRgTEhNcIwloUkKTJNU6hQw57EmEAtNUxyABJLQARp2uWtbfTbG1WqVu8QUhS5N1ThFKKUCc4ZxS6__0GXV2LL9bqtgQiTdqZtOJbZyzppMrW2-0najAKttfaqtT-3qa-3VPrGJVyY9yN--WjDuwHdemM3_SSp8ibrIH4Tecyw</recordid><startdate>202001</startdate><enddate>202001</enddate><creator>Kwong, A.</creator><creator>Kim, W. R.</creator><creator>Lake, J. R.</creator><creator>Smith, J. M.</creator><creator>Schladt, D. P.</creator><creator>Skeans, M. A.</creator><creator>Noreen, S. M.</creator><creator>Foutz, J.</creator><creator>Miller, E.</creator><creator>Snyder, J. J.</creator><creator>Israni, A. K.</creator><creator>Kasiske, B. L.</creator><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>202001</creationdate><title>OPTN/SRTR 2018 Annual Data Report: Liver</title><author>Kwong, A. ; Kim, W. R. ; Lake, J. R. ; Smith, J. M. ; Schladt, D. P. ; Skeans, M. A. ; Noreen, S. M. ; Foutz, J. ; Miller, E. ; Snyder, J. J. ; Israni, A. K. ; Kasiske, B. L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3884-51f7ac73191e56f257b1664468a20b0823cd14a2d8ad1055ba21b6a3d071812c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Acuity</topic><topic>allocation</topic><topic>Children</topic><topic>Diabetes mellitus</topic><topic>distribution</topic><topic>Fatty liver</topic><topic>Geography</topic><topic>Graft Survival</topic><topic>Hepatitis</topic><topic>Hepatitis C</topic><topic>Hepatocellular carcinoma</topic><topic>Humans</topic><topic>Liver diseases</topic><topic>Liver transplant</topic><topic>Liver transplantation</topic><topic>Liver Transplantation - statistics & numerical data</topic><topic>Liver transplants</topic><topic>Pediatrics</topic><topic>Registries</topic><topic>Resource Allocation</topic><topic>Survival</topic><topic>Tissue and Organ Procurement - methods</topic><topic>Tissue Donors - supply & distribution</topic><topic>Transplants & implants</topic><topic>United States</topic><topic>waiting list</topic><topic>Waiting Lists</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kwong, A.</creatorcontrib><creatorcontrib>Kim, W. R.</creatorcontrib><creatorcontrib>Lake, J. R.</creatorcontrib><creatorcontrib>Smith, J. M.</creatorcontrib><creatorcontrib>Schladt, D. P.</creatorcontrib><creatorcontrib>Skeans, M. A.</creatorcontrib><creatorcontrib>Noreen, S. M.</creatorcontrib><creatorcontrib>Foutz, J.</creatorcontrib><creatorcontrib>Miller, E.</creatorcontrib><creatorcontrib>Snyder, J. J.</creatorcontrib><creatorcontrib>Israni, A. K.</creatorcontrib><creatorcontrib>Kasiske, B. L.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of transplantation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kwong, A.</au><au>Kim, W. R.</au><au>Lake, J. R.</au><au>Smith, J. M.</au><au>Schladt, D. P.</au><au>Skeans, M. A.</au><au>Noreen, S. M.</au><au>Foutz, J.</au><au>Miller, E.</au><au>Snyder, J. J.</au><au>Israni, A. K.</au><au>Kasiske, B. L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>OPTN/SRTR 2018 Annual Data Report: Liver</atitle><jtitle>American journal of transplantation</jtitle><addtitle>Am J Transplant</addtitle><date>2020-01</date><risdate>2020</risdate><volume>20</volume><issue>s1</issue><spage>193</spage><epage>299</epage><pages>193-299</pages><issn>1600-6135</issn><eissn>1600-6143</eissn><abstract>Data on adult liver transplants performed in the US in 2018 are notable for (1) continued growth in numbers of new waitlist registrants (11,844) and transplants performed (8250); (2) continued increase in the transplant rate (54.5 per 100 waitlist‐years); (3) a precipitous decline in waitlist registrations and transplants for hepatitis‐C‐related indications; (4) increases in waitlist registrants and recipients with alcoholic liver disease and with clinical profiles consistent with non‐alcoholic fatty liver disease; (5) increased use of hepatitis C virus antibody‐positive donor livers; and (6) continued improvement in graft survival despite changing recipient characteristics such as older age and higher rates of obesity and diabetes. Variability in transplant rates remained by candidate race, hepatocellular carcinoma status, urgency status, and geography. The volume of pediatric liver transplants was relatively unchanged. The highest rate of pre‐transplant mortality persisted for children aged younger than 1 year. Children underwent transplant at higher acuity than in the past, as evidenced by higher model for end‐stage liver disease/pediatric end‐stage liver disease scores and listings at status 1A and 1B at transplant. Despite higher illness severity scores at transplant, pediatric graft and patient survival posttransplant have improved over time.</abstract><cop>United States</cop><pub>Elsevier Limited</pub><pmid>31898413</pmid><doi>10.1111/ajt.15674</doi><tpages>107</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1600-6135 |
| ispartof | American journal of transplantation, 2020-01, Vol.20 (s1), p.193-299 |
| issn | 1600-6135 1600-6143 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2333605400 |
| source | MEDLINE; Wiley Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Acuity allocation Children Diabetes mellitus distribution Fatty liver Geography Graft Survival Hepatitis Hepatitis C Hepatocellular carcinoma Humans Liver diseases Liver transplant Liver transplantation Liver Transplantation - statistics & numerical data Liver transplants Pediatrics Registries Resource Allocation Survival Tissue and Organ Procurement - methods Tissue Donors - supply & distribution Transplants & implants United States waiting list Waiting Lists |
| title | OPTN/SRTR 2018 Annual Data Report: Liver |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T07%3A40%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=OPTN/SRTR%202018%20Annual%20Data%20Report:%20Liver&rft.jtitle=American%20journal%20of%20transplantation&rft.au=Kwong,%20A.&rft.date=2020-01&rft.volume=20&rft.issue=s1&rft.spage=193&rft.epage=299&rft.pages=193-299&rft.issn=1600-6135&rft.eissn=1600-6143&rft_id=info:doi/10.1111/ajt.15674&rft_dat=%3Cproquest_cross%3E2333605400%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2331928300&rft_id=info:pmid/31898413&rfr_iscdi=true |