The relationship between serum clozapine concentrations and hematological parameters by a validated mass spectrometric method

•The LC–MS/MS method is robust, fast, simple and cost-effective.•Norclozapine and clozapine-N -oxide were also determined by this method.•Serum lipid and glucose levels increased in patients using clozapine.•Serum clozapine levels were positively correlated with total cholesterol levels.•Serum cloza...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2020-02, Vol.180, p.113056-113056, Article 113056
Hauptverfasser:	Kamil Gharab, Karam Mazin, Onmaz, Duygu Eryavuz, Abusoglu, Sedat, Aydin, Memduha, Sivrikaya, Abdullah, Tok, Oguzhan, Abusoglu, Gulsum, Unlu, Ali
Format:	Artikel
Sprache:	eng
Schlagworte:	Clozapine Side effects Tandem mass spectrometry Therapeutic drug monitoring
Online-Zugang:	Volltext
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