Comparative analysis of the human serum N-glycome in lung cancer, COPD and their comorbidity using capillary electrophoresis

•Comparative analysis of serum N-Glycome between pathological and control samples.•61 N-glycan structures were identified in the pooled control human serum sample.•13 N-glycan was found as potential glycobiomarkers with significant changes.•Changes of specific N-glycan subclasses may hold essential...

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Veröffentlicht in:	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Analytical technologies in the biomedical and life sciences, 2020-01, Vol.1137, p.121913-121913, Article 121913
Hauptverfasser:	Mészáros, Brigitta, Járvás, Gábor, Farkas, Anna, Szigeti, Márton, Kovács, Zsuzsanna, Kun, Renáta, Szabó, Miklós, Csánky, Eszter, Guttman, András
Format:	Artikel
Sprache:	eng
Schlagworte:	capillary electrophoresis Comorbidity Electrophoresis, Capillary - methods Glycomics human serum Humans Lung Neoplasms - blood Lung Neoplasms - epidemiology Lung Neoplasms - metabolism N-linked glycan Pilot Projects Polysaccharides - blood Polysaccharides - chemistry Pulmonary Disease, Chronic Obstructive - blood Pulmonary Disease, Chronic Obstructive - epidemiology Pulmonary Disease, Chronic Obstructive - metabolism pulmonary diseases Reproducibility of Results
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