Fluorine-18: A radionuclide with diverse range of radiochemistry and synthesis strategies for target based PET diagnosis

Fluorine-18 is one of the most widely used radionuclides for the production of radiopharmaceuticals for positron emission tomography (PET). The radiolabeling methods like nucleophilic, electrophilic, Cu mediated mechanisms or prosthetic groups are widely using to achieve high regioselective radioche...

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Veröffentlicht in:	European journal of medicinal chemistry 2020-02, Vol.187, p.111979-111979, Article 111979
Hauptverfasser:	Goud, Nerella Sridhar, Joshi, Raman Kumar, Bharath, Rose Dawn, Kumar, Pardeep
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carbonic Anhydrases - metabolism Enzyme Inhibitors - chemical synthesis Enzyme Inhibitors - chemistry Enzyme Inhibitors - pharmacology ErbB Receptors - antagonists & inhibitors ErbB Receptors - metabolism Fluorine Radioisotopes Fluorine-18 Humans Neoplasms - diagnostic imaging Neoplasms - drug therapy Neoplasms - metabolism Nervous System Diseases - diagnostic imaging Nervous System Diseases - drug therapy Nervous System Diseases - metabolism Neurology Oncology PET Poly(ADP-ribose) Polymerases - metabolism Positron-Emission Tomography Radiopharmaceuticals - chemical synthesis Radiopharmaceuticals - chemistry Radiopharmaceuticals - pharmacology Receptor Protein-Tyrosine Kinases - antagonists & inhibitors Receptor Protein-Tyrosine Kinases - metabolism
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