Rational Design and In Vitro Evaluation of Novel Peptides Binding to Neuroligin‑1 for Synaptic Targeting

Neuroligin-1 (NL1) is a postsynaptic cell adhesion protein that plays a crucial role in synapsis and signaling between neurons. Due to its clustered distribution in synaptic clefts, NL1 appears as a novel potential site for synaptic targeting purposes. In this work, in silico protein topography anal...

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Veröffentlicht in:Journal of chemical information and modeling 2020-02, Vol.60 (2), p.995-1004
Hauptverfasser: Vásquez, Pilar, Vidal, Felipe, Torres, Josefa, Jiménez, Verónica A, Guzmán, Leonardo
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Sprache:eng
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