Metabolic Network Abnormalities in Drug‐Naïve Parkinson's Disease

Background An ideal imaging biomarker for a neurodegenerative disorder should be able to measure abnormalities in the earliest stages of the disease. Objective We investigated metabolic network changes in two independent cohorts of drug‐naïve Parkinson's disease (PD) patients who have not been...

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Veröffentlicht in:	Movement disorders 2020-04, Vol.35 (4), p.587-594
Hauptverfasser:	Schindlbeck, Katharina A., Lucas‐Jiménez, Olaia, Tang, Chris C., Morbelli, Silvia, Arnaldi, Dario, Pardini, Matteo, Pagani, Marco, Ibarretxe‐Bilbao, Naroa, Ojeda, Natalia, Nobili, Flavio, Eidelberg, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Dopamine receptors drug naïve Humans imaging biomarker Italy Levodopa Metabolic networks Metabolic Networks and Pathways Metabolism Movement disorders network analysis Neurodegenerative diseases Parkinson Disease - diagnostic imaging Parkinson Disease - drug therapy Parkinson's disease Patients PET Pharmaceutical Preparations Positron emission tomography
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