Production of osteogenic and angiogenic factors by microencapsulated adipose stem cells varies with culture conditions

Growth factors produced by stem cells aid in the bone repair process. We investigated the ability of encapsulated rat adipose‐derived stem cells (rASCs) treated with osteogenic media (OM) to produce growth factors, and determined the optimal combination of OM components that will lead to the product...

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Veröffentlicht in:	Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2020-07, Vol.108 (5), p.1857-1867
Hauptverfasser:	Leslie, Shirae K., Cohen, David Joshua, Boyan, Barbara D., Schwartz, Zvi
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Biomedical materials bone formation Bone growth Bone healing Bone morphogenetic protein 2 Cell culture cell encapsulation Dexamethasone Fibroblast growth factors Growth factors hydrogel Materials research Materials science Mice Microspheres Nanoparticles protein secretion Reduction Regeneration Regeneration (physiology) Stem cell transplantation Stem cells Tissue engineering Vascular endothelial growth factor
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