Circulating Exosomal miR‐20b‐5p Inhibition Restores Wnt9b Signaling and Reverses Diabetes‐Associated Impaired Wound Healing

At present, developing therapeutic strategies to improve wound healing in individuals with diabetes remains challenging. Exosomes represent a promising nanomaterial from which microRNAs (miRNAs) can be isolated. These miRNAs have the potential to exert therapeutic effects, and thus, determining the...

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Veröffentlicht in:	Small (Weinheim an der Bergstrasse, Germany) Germany), 2020-01, Vol.16 (3), p.e1904044-n/a
Hauptverfasser:	Xiong, Yuan, Chen, Lang, Yan, Chenchen, Zhou, Wu, Endo, Yori, Liu, Jing, Hu, Liangcong, Hu, Yiqiang, Mi, Bobin, Liu, Guohui
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animals Case-Control Studies Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - metabolism Diabetes Mellitus, Type 2 - physiopathology Endothelial cells Endothelium exosomes Exosomes - metabolism Human Umbilical Vein Endothelial Cells Humans Mice MicroRNAs MicroRNAs - antagonists & inhibitors MicroRNAs - blood miR‐20b‐5p Nanomaterials Nanotechnology Signaling type 2 diabetes Wnt Proteins - metabolism Wound Healing wounds
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