Protection of White Leghorn chickens by recombinant fowlpox vector vaccine with an updated H5 insert against Mexican H5N2 avian influenza viruses

•H5N2 LPAI viruses in Mexico since 1994 have drifted away from vaccine seed strains.•rFPV-H5/2016 vaccine protected chickens against 1995 H5/HP virus challenge.•rFPV-H5/2016 vaccine decreased shedding of 2010 H5/LP and 1995 H5/HP viruses.•rFPV-H5/2016 vaccine could be used as a primer in a prime-boo...

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Veröffentlicht in:	Vaccine 2020-02, Vol.38 (6), p.1526-1534
Hauptverfasser:	Bertran, Kateri, Criado, Miria Ferreira, Lee, Dong-Hun, Killmaster, Lindsay, Sá e Silva, Mariana, Lucio, Eduardo, Widener, Justin, Pritchard, Nikki, Atkins, Emily, Mebatsion, Teshome, Swayne, David E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigenic drift Antigens Avian flu Avian influenza Biosecurity Birds Chickens Divergence Drift Fowlpox Fowlpox - prevention & control H5N2 Hemagglutinin Glycoproteins, Influenza Virus - genetics Hemagglutinin Glycoproteins, Influenza Virus - immunology Hemagglutinins Immunization Influenza Influenza A Virus, H5N2 Subtype - immunology Influenza Vaccines - administration & dosage Influenza Vaccines - genetics Mexico Pathogenicity Pathogens Phylogenetics Phylogeny Poultry Strains (organisms) Tissue culture Vaccine Vaccine efficacy Vaccines Vaccines, Synthetic - genetics Viruses
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