The mismatch repair system is not affected in medullary thyroid carcinoma independent of stromal desmoplasia or ret proto-oncogene mutation

Medullary thyroid carcinoma (MTC) is an aggressive neuroendocrine neoplasia of the thyroid with 10 year overall survival of 50% and limited therapeutic options. High tumor mutational burden because of microsatellite instability (MSI) seems to be a predictor of response to immune checkpoint inhibitor...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Annals of diagnostic pathology 2020-02, Vol.44, p.151445-151445, Article 151445
Hauptverfasser:	Ingenwerth, Marc, Goetz, Moritz, Schmid, Kurt W., Theurer, Sarah
Format:	Artikel
Sprache:	eng
Schlagworte:	Mismatch repair MSI MTC PDL-1 ret-mutation Stromal desmoplasia
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!