Prevalence of dysphagia in a consecutive cohort of subjects with MS using fibre-optic endoscopy
Introduction Multiple sclerosis (MS) refers to chronic inflammation of the central nervous system including the brain and spinal cord. Dysphagia is a symptom that represents challenges in clinical practice. The aim of the present study was to evaluate the prevalence of dysphagia in an Italian cohort...
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| Veröffentlicht in: | Neurological sciences 2020-05, Vol.41 (5), p.1075-1079 |
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| creator | Solaro, C. Cuccaro, A. Gamberini, G. Patti, F. D’Amico, E. Bergamaschi, R. Berra, E. Giusti, A. Rezzani, C. Messmer Uccelli, M. Grasso, M. G. |
| description | Introduction
Multiple sclerosis (MS) refers to chronic inflammation of the central nervous system including the brain and spinal cord. Dysphagia is a symptom that represents challenges in clinical practice. The aim of the present study was to evaluate the prevalence of dysphagia in an Italian cohort of subjects with MS using the Dysphagia Outcome Severity Score (DOSS), based on fibre-optic endoscopy, and determine factors that correlate with the presence of swallowing problems.
Matherials and Methods
Data were collected in a multicentre study from a consecutive sample of MS patients, irrespective of self-reported dysphagia. The study included 215 subjects. Possible scores for DOSS range from 7 to 1, with 7 indicating normal swallowing.
Results
One hundred twenty-four (57.7%) subjects demonstrated abnormal swallowing and 57 (26.5%) of these had swallowing problems that required nutrition/diet modifications when evaluated objectively with fibre-optic endoscopy. Subjects with dysphagia were more severely disabled and more often had a progressive form of MS, compared to MS subjects with normal swallowing. In subjects with EDSS, |
| doi_str_mv | 10.1007/s10072-019-04198-3 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2329730397</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2329730397</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-7f3bec1ccc025974cc96dc1967911d96099afba1924306ab696c6b3138a7e0c43</originalsourceid><addsrcrecordid>eNp9kE1v1DAQhi0EomXhD_RQWeLCJcWTycbxsar4klqBBJwtZzLZ9Wo3DnbSav89XnYpUg9cZkaaZ15bjxAXoK5AKf0-HWpZKDCFqsA0BT4T57A0qsBKN89PMzS6OhOvUtoopaACfCnOEJoasdTnwn6LfO-2PBDL0Mtun8a1W3kn_SCdpDAkpnny95zndYjTAUpzu2Gaknzw01refZdz8sNK9r6NXIRx8iR56EKiMO5fixe92yZ-c-oL8fPjhx83n4vbr5--3FzfFoR6ORW6x5YJiEiVS6MrIlN3BKbWBqAztTLG9a0DU1aoatfWpqa6RcDGaVZU4UK8O-aOMfyaOU125xPxdusGDnOyJZZGo8JcFuLtE3QT5jjk32XKaNBNdpmp8khRDClF7u0Y_c7FvQVlD-LtUb_N-u0f_Rbz0eUpem533D2e_PWdATwCKa-GFcd_b_8n9jfCN4-p</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2397178198</pqid></control><display><type>article</type><title>Prevalence of dysphagia in a consecutive cohort of subjects with MS using fibre-optic endoscopy</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Solaro, C. ; Cuccaro, A. ; Gamberini, G. ; Patti, F. ; D’Amico, E. ; Bergamaschi, R. ; Berra, E. ; Giusti, A. ; Rezzani, C. ; Messmer Uccelli, M. ; Grasso, M. G.</creator><creatorcontrib>Solaro, C. ; Cuccaro, A. ; Gamberini, G. ; Patti, F. ; D’Amico, E. ; Bergamaschi, R. ; Berra, E. ; Giusti, A. ; Rezzani, C. ; Messmer Uccelli, M. ; Grasso, M. G.</creatorcontrib><description>Introduction
Multiple sclerosis (MS) refers to chronic inflammation of the central nervous system including the brain and spinal cord. Dysphagia is a symptom that represents challenges in clinical practice. The aim of the present study was to evaluate the prevalence of dysphagia in an Italian cohort of subjects with MS using the Dysphagia Outcome Severity Score (DOSS), based on fibre-optic endoscopy, and determine factors that correlate with the presence of swallowing problems.
Matherials and Methods
Data were collected in a multicentre study from a consecutive sample of MS patients, irrespective of self-reported dysphagia. The study included 215 subjects. Possible scores for DOSS range from 7 to 1, with 7 indicating normal swallowing.
Results
One hundred twenty-four (57.7%) subjects demonstrated abnormal swallowing and 57 (26.5%) of these had swallowing problems that required nutrition/diet modifications when evaluated objectively with fibre-optic endoscopy. Subjects with dysphagia were more severely disabled and more often had a progressive form of MS, compared to MS subjects with normal swallowing. In subjects with EDSS, < 4, 8 (13.3%), had a DOSS < 4. Seventy-five percent of subjects older than 60 years of age had dysphagia.
Conclusion
In this sample of MS patients, more nearly 60% showed swallowing problems.</description><identifier>ISSN: 1590-1874</identifier><identifier>EISSN: 1590-3478</identifier><identifier>DOI: 10.1007/s10072-019-04198-3</identifier><identifier>PMID: 31863327</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Central nervous system ; Cohort Studies ; Deglutition Disorders - complications ; Deglutition Disorders - diagnosis ; Deglutition Disorders - epidemiology ; Dysphagia ; Endoscopy ; Endoscopy - methods ; Female ; Humans ; Italy - epidemiology ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Multiple sclerosis ; Multiple Sclerosis - complications ; Multiple Sclerosis - epidemiology ; Neurology ; Neuroradiology ; Neurosciences ; Neurosurgery ; Optical Fibers ; Original Article ; Prevalence ; Psychiatry ; Severity of Illness Index ; Spinal cord ; Swallowing</subject><ispartof>Neurological sciences, 2020-05, Vol.41 (5), p.1075-1079</ispartof><rights>Fondazione Società Italiana di Neurologia 2019</rights><rights>Fondazione Società Italiana di Neurologia 2019.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-7f3bec1ccc025974cc96dc1967911d96099afba1924306ab696c6b3138a7e0c43</citedby><cites>FETCH-LOGICAL-c375t-7f3bec1ccc025974cc96dc1967911d96099afba1924306ab696c6b3138a7e0c43</cites><orcidid>0000-0002-6713-4623</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10072-019-04198-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10072-019-04198-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31863327$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Solaro, C.</creatorcontrib><creatorcontrib>Cuccaro, A.</creatorcontrib><creatorcontrib>Gamberini, G.</creatorcontrib><creatorcontrib>Patti, F.</creatorcontrib><creatorcontrib>D’Amico, E.</creatorcontrib><creatorcontrib>Bergamaschi, R.</creatorcontrib><creatorcontrib>Berra, E.</creatorcontrib><creatorcontrib>Giusti, A.</creatorcontrib><creatorcontrib>Rezzani, C.</creatorcontrib><creatorcontrib>Messmer Uccelli, M.</creatorcontrib><creatorcontrib>Grasso, M. G.</creatorcontrib><title>Prevalence of dysphagia in a consecutive cohort of subjects with MS using fibre-optic endoscopy</title><title>Neurological sciences</title><addtitle>Neurol Sci</addtitle><addtitle>Neurol Sci</addtitle><description>Introduction
Multiple sclerosis (MS) refers to chronic inflammation of the central nervous system including the brain and spinal cord. Dysphagia is a symptom that represents challenges in clinical practice. The aim of the present study was to evaluate the prevalence of dysphagia in an Italian cohort of subjects with MS using the Dysphagia Outcome Severity Score (DOSS), based on fibre-optic endoscopy, and determine factors that correlate with the presence of swallowing problems.
Matherials and Methods
Data were collected in a multicentre study from a consecutive sample of MS patients, irrespective of self-reported dysphagia. The study included 215 subjects. Possible scores for DOSS range from 7 to 1, with 7 indicating normal swallowing.
Results
One hundred twenty-four (57.7%) subjects demonstrated abnormal swallowing and 57 (26.5%) of these had swallowing problems that required nutrition/diet modifications when evaluated objectively with fibre-optic endoscopy. Subjects with dysphagia were more severely disabled and more often had a progressive form of MS, compared to MS subjects with normal swallowing. In subjects with EDSS, < 4, 8 (13.3%), had a DOSS < 4. Seventy-five percent of subjects older than 60 years of age had dysphagia.
Conclusion
In this sample of MS patients, more nearly 60% showed swallowing problems.</description><subject>Central nervous system</subject><subject>Cohort Studies</subject><subject>Deglutition Disorders - complications</subject><subject>Deglutition Disorders - diagnosis</subject><subject>Deglutition Disorders - epidemiology</subject><subject>Dysphagia</subject><subject>Endoscopy</subject><subject>Endoscopy - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Italy - epidemiology</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Multiple sclerosis</subject><subject>Multiple Sclerosis - complications</subject><subject>Multiple Sclerosis - epidemiology</subject><subject>Neurology</subject><subject>Neuroradiology</subject><subject>Neurosciences</subject><subject>Neurosurgery</subject><subject>Optical Fibers</subject><subject>Original Article</subject><subject>Prevalence</subject><subject>Psychiatry</subject><subject>Severity of Illness Index</subject><subject>Spinal cord</subject><subject>Swallowing</subject><issn>1590-1874</issn><issn>1590-3478</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kE1v1DAQhi0EomXhD_RQWeLCJcWTycbxsar4klqBBJwtZzLZ9Wo3DnbSav89XnYpUg9cZkaaZ15bjxAXoK5AKf0-HWpZKDCFqsA0BT4T57A0qsBKN89PMzS6OhOvUtoopaACfCnOEJoasdTnwn6LfO-2PBDL0Mtun8a1W3kn_SCdpDAkpnny95zndYjTAUpzu2Gaknzw01refZdz8sNK9r6NXIRx8iR56EKiMO5fixe92yZ-c-oL8fPjhx83n4vbr5--3FzfFoR6ORW6x5YJiEiVS6MrIlN3BKbWBqAztTLG9a0DU1aoatfWpqa6RcDGaVZU4UK8O-aOMfyaOU125xPxdusGDnOyJZZGo8JcFuLtE3QT5jjk32XKaNBNdpmp8khRDClF7u0Y_c7FvQVlD-LtUb_N-u0f_Rbz0eUpem533D2e_PWdATwCKa-GFcd_b_8n9jfCN4-p</recordid><startdate>20200501</startdate><enddate>20200501</enddate><creator>Solaro, C.</creator><creator>Cuccaro, A.</creator><creator>Gamberini, G.</creator><creator>Patti, F.</creator><creator>D’Amico, E.</creator><creator>Bergamaschi, R.</creator><creator>Berra, E.</creator><creator>Giusti, A.</creator><creator>Rezzani, C.</creator><creator>Messmer Uccelli, M.</creator><creator>Grasso, M. G.</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9-</scope><scope>K9.</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-6713-4623</orcidid></search><sort><creationdate>20200501</creationdate><title>Prevalence of dysphagia in a consecutive cohort of subjects with MS using fibre-optic endoscopy</title><author>Solaro, C. ; Cuccaro, A. ; Gamberini, G. ; Patti, F. ; D’Amico, E. ; Bergamaschi, R. ; Berra, E. ; Giusti, A. ; Rezzani, C. ; Messmer Uccelli, M. ; Grasso, M. G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-7f3bec1ccc025974cc96dc1967911d96099afba1924306ab696c6b3138a7e0c43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Central nervous system</topic><topic>Cohort Studies</topic><topic>Deglutition Disorders - complications</topic><topic>Deglutition Disorders - diagnosis</topic><topic>Deglutition Disorders - epidemiology</topic><topic>Dysphagia</topic><topic>Endoscopy</topic><topic>Endoscopy - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Italy - epidemiology</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Multiple sclerosis</topic><topic>Multiple Sclerosis - complications</topic><topic>Multiple Sclerosis - epidemiology</topic><topic>Neurology</topic><topic>Neuroradiology</topic><topic>Neurosciences</topic><topic>Neurosurgery</topic><topic>Optical Fibers</topic><topic>Original Article</topic><topic>Prevalence</topic><topic>Psychiatry</topic><topic>Severity of Illness Index</topic><topic>Spinal cord</topic><topic>Swallowing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Solaro, C.</creatorcontrib><creatorcontrib>Cuccaro, A.</creatorcontrib><creatorcontrib>Gamberini, G.</creatorcontrib><creatorcontrib>Patti, F.</creatorcontrib><creatorcontrib>D’Amico, E.</creatorcontrib><creatorcontrib>Bergamaschi, R.</creatorcontrib><creatorcontrib>Berra, E.</creatorcontrib><creatorcontrib>Giusti, A.</creatorcontrib><creatorcontrib>Rezzani, C.</creatorcontrib><creatorcontrib>Messmer Uccelli, M.</creatorcontrib><creatorcontrib>Grasso, M. G.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Neurological sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Solaro, C.</au><au>Cuccaro, A.</au><au>Gamberini, G.</au><au>Patti, F.</au><au>D’Amico, E.</au><au>Bergamaschi, R.</au><au>Berra, E.</au><au>Giusti, A.</au><au>Rezzani, C.</au><au>Messmer Uccelli, M.</au><au>Grasso, M. G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of dysphagia in a consecutive cohort of subjects with MS using fibre-optic endoscopy</atitle><jtitle>Neurological sciences</jtitle><stitle>Neurol Sci</stitle><addtitle>Neurol Sci</addtitle><date>2020-05-01</date><risdate>2020</risdate><volume>41</volume><issue>5</issue><spage>1075</spage><epage>1079</epage><pages>1075-1079</pages><issn>1590-1874</issn><eissn>1590-3478</eissn><abstract>Introduction
Multiple sclerosis (MS) refers to chronic inflammation of the central nervous system including the brain and spinal cord. Dysphagia is a symptom that represents challenges in clinical practice. The aim of the present study was to evaluate the prevalence of dysphagia in an Italian cohort of subjects with MS using the Dysphagia Outcome Severity Score (DOSS), based on fibre-optic endoscopy, and determine factors that correlate with the presence of swallowing problems.
Matherials and Methods
Data were collected in a multicentre study from a consecutive sample of MS patients, irrespective of self-reported dysphagia. The study included 215 subjects. Possible scores for DOSS range from 7 to 1, with 7 indicating normal swallowing.
Results
One hundred twenty-four (57.7%) subjects demonstrated abnormal swallowing and 57 (26.5%) of these had swallowing problems that required nutrition/diet modifications when evaluated objectively with fibre-optic endoscopy. Subjects with dysphagia were more severely disabled and more often had a progressive form of MS, compared to MS subjects with normal swallowing. In subjects with EDSS, < 4, 8 (13.3%), had a DOSS < 4. Seventy-five percent of subjects older than 60 years of age had dysphagia.
Conclusion
In this sample of MS patients, more nearly 60% showed swallowing problems.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>31863327</pmid><doi>10.1007/s10072-019-04198-3</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-6713-4623</orcidid></addata></record> |
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| ispartof | Neurological sciences, 2020-05, Vol.41 (5), p.1075-1079 |
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| subjects | Central nervous system Cohort Studies Deglutition Disorders - complications Deglutition Disorders - diagnosis Deglutition Disorders - epidemiology Dysphagia Endoscopy Endoscopy - methods Female Humans Italy - epidemiology Male Medicine Medicine & Public Health Middle Aged Multiple sclerosis Multiple Sclerosis - complications Multiple Sclerosis - epidemiology Neurology Neuroradiology Neurosciences Neurosurgery Optical Fibers Original Article Prevalence Psychiatry Severity of Illness Index Spinal cord Swallowing |
| title | Prevalence of dysphagia in a consecutive cohort of subjects with MS using fibre-optic endoscopy |
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