Establishment of infectious genotype 4 cell culture-derived hepatitis C virus

To establish infectious genotype 4a (GT4a) cell culture-derived hepatitis C virus (HCVcc), we constructed full-length ED43 and 12 mutants possessing single or double mutations that increase ED43 replicon replication, and performed cell culture after RNA transfection. Sequential long-term culture of...

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Veröffentlicht in:Journal of general virology 2020-02, Vol.101 (2), p.188-197
Hauptverfasser: Watanabe, Noriyuki, Suzuki, Takaya, Date, Tomoko, Hussan, Hussein Aly, Hmwe, Su Su, Aizaki, Hideki, Sugiyama, Masaya, Mizokami, Masashi, Delaney Iv, William, Cheng, Guofeng, Muramatsu, Masamichi, Wakita, Takaji
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Sprache:eng
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