miRNA-150-5p promotes hepatic stellate cell proliferation and sensitizes hepatocyte apoptosis during liver fibrosis

To explore the role of miRNA-150-5p (miR-150-5p) in liver fibrosis. miRNA expression profiles, CCl -induced liver fibrosis progression and regression rodent models, quantitative real-time PCR, miR-150-5p mimics and inhibitors, cell proliferation and apoptosis detection, RNA sequencing and bioinforma...

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Veröffentlicht in:	Epigenomics 2020-01, Vol.12 (1), p.53-67
Hauptverfasser:	Chen, Wei, Yan, Xuzhen, Yang, Aiting, Xu, Anjian, Huang, Tao, You, Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Apoptosis Bile Bioinformatics Carbon tetrachloride Cell culture Cell growth Cell proliferation cell specific Datasets Fibrosis Gene expression Gene sequencing hepatic stellate cell hepatocyte Hepatocytes Interferon Liver liver fibrosis Manufacturers miR-150-5p miRNA Olive oil proliferation Regression analysis Ribonucleic acid RNA Stellate cells Studies transcriptome Transcriptomics
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