$Prognostic and predictive value of histogram analysis in patients with non-small cell lung cancer refractory to platinum treated by nivolumab: A multicentre retrospective study$

Prognostic and predictive value of histogram analysis in patients with non-small cell lung cancer refractory to platinum treated by nivolumab: A multicentre retrospective study

•Nivolumab has heterogeneous response and is difficult to predict its efficacy.•Prognosis of patients treated with nivolumab might be enriched by texture analysis.•CT texture analysis was related with overall survival and progression-free survival.•CT texture analysis could help oncologists to selec...

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Veröffentlicht in:	European journal of radiology 2019-09, Vol.118, p.251-256
Hauptverfasser:	Ravanelli, Marco, Agazzi, Giorgio Maria, Milanese, Gianluca, Roca, Elisa, Silva, Mario, Tiseo, Marcello, Rondi, Paolo, Baggi, Alice, Ganeshan, Balaji, Muri, Margherita, Panni, Stefano, Botti, Camilla, Sverzellati, Nicola, Maroldi, Roberto, Berruti, Alfredo, Farina, Davide
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antineoplastic Agents, Immunological - therapeutic use Carcinoma, Non-Small-Cell Lung - diagnostic imaging Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - mortality Disease-Free Survival Drug Resistance, Neoplasm Female Histogram analysis, iRECIST Humans Immunotherapy Lung neoplasms Lung Neoplasms - diagnostic imaging Lung Neoplasms - drug therapy Lung Neoplasms - mortality Male Middle Aged Neoplasms/diagnostic imaging Nivolumab Nivolumab - therapeutic use Platinum Compounds - therapeutic use Prognosis Proportional Hazards Models Retrospective Studies Tomography, X-Ray computed Tomography, X-Ray Computed - methods Treatment Outcome
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