Predicting the mechanical response of the vaginal wall in ball burst tests based on histology
A histologically motivated (HM) coefficient that establishes a link between tissue's microstructure and material model through histological data is used in the prediction of the mechanical properties of vaginal tissue that is subjected to multiaxial loading conditions. Therefore, the material p...
Gespeichert in:
| Veröffentlicht in: | Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2020-07, Vol.108 (5), p.1925-1933 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1933 |
|---|---|
| container_issue | 5 |
| container_start_page | 1925 |
| container_title | Journal of biomedical materials research. Part B, Applied biomaterials |
| container_volume | 108 |
| creator | Ferreira, João P. S. Rynkevic, Rita Martins, Pedro A. L. S. Parente, Marco P. L. Famaey, Nele M. Deprest, Jan Fernandes, António A. |
| description | A histologically motivated (HM) coefficient that establishes a link between tissue's microstructure and material model through histological data is used in the prediction of the mechanical properties of vaginal tissue that is subjected to multiaxial loading conditions. Therefore, the material parameters were based on an HM coefficient obtained from tensile testing and histological data of comparable tissues. Uniaxial tensile test data and histological data were collected from three groups of sheep at different time points in their life cycle, including virgins, pregnant, and parous ewes. From this data, a correlation between material parameters and histological data was obtained. Spherical indentation (ball burst [BB]) tests were then performed in specimens with similar tissue structure. The histological data of these samples were used in conjunction with the correlations already established for the uniaxial samples data, to define the material parameters of the BB samples. Mechanical properties of the BB specimens were predicted through basic histology and using finite element modeling (FEM) simulations, without direct mechanical measurements. The predicted force and displacement values of the FEM simulation displayed a good correlation with the experimental (BB) testing results. No fitting of the BB results was performed. In this way, the use of uniaxial tests coupled with useful histological information offers a promising approach to predicting macroscopic material behavior under multiaxial loading conditions in biomechanics. |
| doi_str_mv | 10.1002/jbm.b.34534 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2327941659</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2327941659</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3604-777c0847a6d8331b52df44b6821f5b7c665cdac12f969825677cb68e3b8788e43</originalsourceid><addsrcrecordid>eNp9kLtLBDEQxoMovit7CdgIcufmnS1VfKJooaWEJJu9y7G7OZNd5f57c55aWDjNDPP9-Jj5ADhAxRgVBT6dmXZsxoQyQtfANmIMj2gp0frvLMgW2ElplmFeMLIJtgiSNGtiG7w-RVd52_tuAvupg62zU915qxsYXZqHLjkY6i_pXU98l_cfummg76BZdjPE1MPepT7lRXIVDB2c-tSHJkwWe2Cj1k1y-999F7xcXT5f3IzuH69vL87uR5bwgo6EELaQVGheSUKQYbiqKTVcYlQzIyznzFbaIlyXvJSY8cxn1REjhZSOkl1wvPKdx_A25GNU65N1TaM7F4akMMGipIizMqNHf9BZGGL-a0mVNJfkJFMnK8rGkFJ0tZpH3-q4UKhQy9RVTl0Z9ZV6pg-_PQfTuuqX_Yk5A3gFfPjGLf7zUnfnD-cr10_lfYwU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2394444863</pqid></control><display><type>article</type><title>Predicting the mechanical response of the vaginal wall in ball burst tests based on histology</title><source>Wiley Online Library - AutoHoldings Journals</source><creator>Ferreira, João P. S. ; Rynkevic, Rita ; Martins, Pedro A. L. S. ; Parente, Marco P. L. ; Famaey, Nele M. ; Deprest, Jan ; Fernandes, António A.</creator><creatorcontrib>Ferreira, João P. S. ; Rynkevic, Rita ; Martins, Pedro A. L. S. ; Parente, Marco P. L. ; Famaey, Nele M. ; Deprest, Jan ; Fernandes, António A.</creatorcontrib><description>A histologically motivated (HM) coefficient that establishes a link between tissue's microstructure and material model through histological data is used in the prediction of the mechanical properties of vaginal tissue that is subjected to multiaxial loading conditions. Therefore, the material parameters were based on an HM coefficient obtained from tensile testing and histological data of comparable tissues. Uniaxial tensile test data and histological data were collected from three groups of sheep at different time points in their life cycle, including virgins, pregnant, and parous ewes. From this data, a correlation between material parameters and histological data was obtained. Spherical indentation (ball burst [BB]) tests were then performed in specimens with similar tissue structure. The histological data of these samples were used in conjunction with the correlations already established for the uniaxial samples data, to define the material parameters of the BB samples. Mechanical properties of the BB specimens were predicted through basic histology and using finite element modeling (FEM) simulations, without direct mechanical measurements. The predicted force and displacement values of the FEM simulation displayed a good correlation with the experimental (BB) testing results. No fitting of the BB results was performed. In this way, the use of uniaxial tests coupled with useful histological information offers a promising approach to predicting macroscopic material behavior under multiaxial loading conditions in biomechanics.</description><identifier>ISSN: 1552-4973</identifier><identifier>EISSN: 1552-4981</identifier><identifier>DOI: 10.1002/jbm.b.34534</identifier><identifier>PMID: 31845527</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley & Sons, Inc</publisher><subject>biomechanical properties ; Biomechanics ; Biomedical materials ; Burst tests ; Computer simulation ; Correlation ; Finite element method ; genetic algorithm ; Histology ; hyperelastic model ; Indentation ; Life cycles ; Materials research ; Materials science ; Mathematical models ; Mechanical analysis ; Mechanical measurement ; Mechanical properties ; Parameters ; Sheep ; Tensile tests ; Tissues ; Uniaxial tests ; Vagina ; vaginal tissue</subject><ispartof>Journal of biomedical materials research. Part B, Applied biomaterials, 2020-07, Vol.108 (5), p.1925-1933</ispartof><rights>2019 Wiley Periodicals, Inc.</rights><rights>2020 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3604-777c0847a6d8331b52df44b6821f5b7c665cdac12f969825677cb68e3b8788e43</citedby><cites>FETCH-LOGICAL-c3604-777c0847a6d8331b52df44b6821f5b7c665cdac12f969825677cb68e3b8788e43</cites><orcidid>0000-0003-4310-2915</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjbm.b.34534$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjbm.b.34534$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31845527$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ferreira, João P. S.</creatorcontrib><creatorcontrib>Rynkevic, Rita</creatorcontrib><creatorcontrib>Martins, Pedro A. L. S.</creatorcontrib><creatorcontrib>Parente, Marco P. L.</creatorcontrib><creatorcontrib>Famaey, Nele M.</creatorcontrib><creatorcontrib>Deprest, Jan</creatorcontrib><creatorcontrib>Fernandes, António A.</creatorcontrib><title>Predicting the mechanical response of the vaginal wall in ball burst tests based on histology</title><title>Journal of biomedical materials research. Part B, Applied biomaterials</title><addtitle>J Biomed Mater Res B Appl Biomater</addtitle><description>A histologically motivated (HM) coefficient that establishes a link between tissue's microstructure and material model through histological data is used in the prediction of the mechanical properties of vaginal tissue that is subjected to multiaxial loading conditions. Therefore, the material parameters were based on an HM coefficient obtained from tensile testing and histological data of comparable tissues. Uniaxial tensile test data and histological data were collected from three groups of sheep at different time points in their life cycle, including virgins, pregnant, and parous ewes. From this data, a correlation between material parameters and histological data was obtained. Spherical indentation (ball burst [BB]) tests were then performed in specimens with similar tissue structure. The histological data of these samples were used in conjunction with the correlations already established for the uniaxial samples data, to define the material parameters of the BB samples. Mechanical properties of the BB specimens were predicted through basic histology and using finite element modeling (FEM) simulations, without direct mechanical measurements. The predicted force and displacement values of the FEM simulation displayed a good correlation with the experimental (BB) testing results. No fitting of the BB results was performed. In this way, the use of uniaxial tests coupled with useful histological information offers a promising approach to predicting macroscopic material behavior under multiaxial loading conditions in biomechanics.</description><subject>biomechanical properties</subject><subject>Biomechanics</subject><subject>Biomedical materials</subject><subject>Burst tests</subject><subject>Computer simulation</subject><subject>Correlation</subject><subject>Finite element method</subject><subject>genetic algorithm</subject><subject>Histology</subject><subject>hyperelastic model</subject><subject>Indentation</subject><subject>Life cycles</subject><subject>Materials research</subject><subject>Materials science</subject><subject>Mathematical models</subject><subject>Mechanical analysis</subject><subject>Mechanical measurement</subject><subject>Mechanical properties</subject><subject>Parameters</subject><subject>Sheep</subject><subject>Tensile tests</subject><subject>Tissues</subject><subject>Uniaxial tests</subject><subject>Vagina</subject><subject>vaginal tissue</subject><issn>1552-4973</issn><issn>1552-4981</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kLtLBDEQxoMovit7CdgIcufmnS1VfKJooaWEJJu9y7G7OZNd5f57c55aWDjNDPP9-Jj5ADhAxRgVBT6dmXZsxoQyQtfANmIMj2gp0frvLMgW2ElplmFeMLIJtgiSNGtiG7w-RVd52_tuAvupg62zU915qxsYXZqHLjkY6i_pXU98l_cfummg76BZdjPE1MPepT7lRXIVDB2c-tSHJkwWe2Cj1k1y-999F7xcXT5f3IzuH69vL87uR5bwgo6EELaQVGheSUKQYbiqKTVcYlQzIyznzFbaIlyXvJSY8cxn1REjhZSOkl1wvPKdx_A25GNU65N1TaM7F4akMMGipIizMqNHf9BZGGL-a0mVNJfkJFMnK8rGkFJ0tZpH3-q4UKhQy9RVTl0Z9ZV6pg-_PQfTuuqX_Yk5A3gFfPjGLf7zUnfnD-cr10_lfYwU</recordid><startdate>202007</startdate><enddate>202007</enddate><creator>Ferreira, João P. S.</creator><creator>Rynkevic, Rita</creator><creator>Martins, Pedro A. L. S.</creator><creator>Parente, Marco P. L.</creator><creator>Famaey, Nele M.</creator><creator>Deprest, Jan</creator><creator>Fernandes, António A.</creator><general>John Wiley & Sons, Inc</general><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7T7</scope><scope>7TA</scope><scope>7TB</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>JG9</scope><scope>JQ2</scope><scope>K9.</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4310-2915</orcidid></search><sort><creationdate>202007</creationdate><title>Predicting the mechanical response of the vaginal wall in ball burst tests based on histology</title><author>Ferreira, João P. S. ; Rynkevic, Rita ; Martins, Pedro A. L. S. ; Parente, Marco P. L. ; Famaey, Nele M. ; Deprest, Jan ; Fernandes, António A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3604-777c0847a6d8331b52df44b6821f5b7c665cdac12f969825677cb68e3b8788e43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>biomechanical properties</topic><topic>Biomechanics</topic><topic>Biomedical materials</topic><topic>Burst tests</topic><topic>Computer simulation</topic><topic>Correlation</topic><topic>Finite element method</topic><topic>genetic algorithm</topic><topic>Histology</topic><topic>hyperelastic model</topic><topic>Indentation</topic><topic>Life cycles</topic><topic>Materials research</topic><topic>Materials science</topic><topic>Mathematical models</topic><topic>Mechanical analysis</topic><topic>Mechanical measurement</topic><topic>Mechanical properties</topic><topic>Parameters</topic><topic>Sheep</topic><topic>Tensile tests</topic><topic>Tissues</topic><topic>Uniaxial tests</topic><topic>Vagina</topic><topic>vaginal tissue</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ferreira, João P. S.</creatorcontrib><creatorcontrib>Rynkevic, Rita</creatorcontrib><creatorcontrib>Martins, Pedro A. L. S.</creatorcontrib><creatorcontrib>Parente, Marco P. L.</creatorcontrib><creatorcontrib>Famaey, Nele M.</creatorcontrib><creatorcontrib>Deprest, Jan</creatorcontrib><creatorcontrib>Fernandes, António A.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of biomedical materials research. Part B, Applied biomaterials</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ferreira, João P. S.</au><au>Rynkevic, Rita</au><au>Martins, Pedro A. L. S.</au><au>Parente, Marco P. L.</au><au>Famaey, Nele M.</au><au>Deprest, Jan</au><au>Fernandes, António A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predicting the mechanical response of the vaginal wall in ball burst tests based on histology</atitle><jtitle>Journal of biomedical materials research. Part B, Applied biomaterials</jtitle><addtitle>J Biomed Mater Res B Appl Biomater</addtitle><date>2020-07</date><risdate>2020</risdate><volume>108</volume><issue>5</issue><spage>1925</spage><epage>1933</epage><pages>1925-1933</pages><issn>1552-4973</issn><eissn>1552-4981</eissn><abstract>A histologically motivated (HM) coefficient that establishes a link between tissue's microstructure and material model through histological data is used in the prediction of the mechanical properties of vaginal tissue that is subjected to multiaxial loading conditions. Therefore, the material parameters were based on an HM coefficient obtained from tensile testing and histological data of comparable tissues. Uniaxial tensile test data and histological data were collected from three groups of sheep at different time points in their life cycle, including virgins, pregnant, and parous ewes. From this data, a correlation between material parameters and histological data was obtained. Spherical indentation (ball burst [BB]) tests were then performed in specimens with similar tissue structure. The histological data of these samples were used in conjunction with the correlations already established for the uniaxial samples data, to define the material parameters of the BB samples. Mechanical properties of the BB specimens were predicted through basic histology and using finite element modeling (FEM) simulations, without direct mechanical measurements. The predicted force and displacement values of the FEM simulation displayed a good correlation with the experimental (BB) testing results. No fitting of the BB results was performed. In this way, the use of uniaxial tests coupled with useful histological information offers a promising approach to predicting macroscopic material behavior under multiaxial loading conditions in biomechanics.</abstract><cop>Hoboken, USA</cop><pub>John Wiley & Sons, Inc</pub><pmid>31845527</pmid><doi>10.1002/jbm.b.34534</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0003-4310-2915</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1552-4973 |
| ispartof | Journal of biomedical materials research. Part B, Applied biomaterials, 2020-07, Vol.108 (5), p.1925-1933 |
| issn | 1552-4973 1552-4981 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2327941659 |
| source | Wiley Online Library - AutoHoldings Journals |
| subjects | biomechanical properties Biomechanics Biomedical materials Burst tests Computer simulation Correlation Finite element method genetic algorithm Histology hyperelastic model Indentation Life cycles Materials research Materials science Mathematical models Mechanical analysis Mechanical measurement Mechanical properties Parameters Sheep Tensile tests Tissues Uniaxial tests Vagina vaginal tissue |
| title | Predicting the mechanical response of the vaginal wall in ball burst tests based on histology |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-19T10%3A39%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Predicting%20the%20mechanical%20response%20of%20the%20vaginal%20wall%20in%20ball%20burst%20tests%20based%20on%20histology&rft.jtitle=Journal%20of%20biomedical%20materials%20research.%20Part%20B,%20Applied%20biomaterials&rft.au=Ferreira,%20Jo%C3%A3o%20P.%20S.&rft.date=2020-07&rft.volume=108&rft.issue=5&rft.spage=1925&rft.epage=1933&rft.pages=1925-1933&rft.issn=1552-4973&rft.eissn=1552-4981&rft_id=info:doi/10.1002/jbm.b.34534&rft_dat=%3Cproquest_cross%3E2327941659%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2394444863&rft_id=info:pmid/31845527&rfr_iscdi=true |