Highly sensitive and selective non-enzymatic glucose detection based on indigo carmine/hemin/H2O2 chemiluminescence
A new chemiluminescence (CL) system, indigo carmine/glucose/hemin/H2O2, has been found and developed for non-enzymatic detection of indigo carmine (IC) and glucose. The CL response increases linearly with IC concentrations from 3.2 μM to 10 mM and glucose concentrations from 0.06 μM to 3.5 mM. The d...
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| Veröffentlicht in: | Analyst (London) 2020-02, Vol.145 (3), p.1041-1046 |
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| container_title | Analyst (London) |
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| creator | Tadesse Haile Fereja Shimeles Addisu Kitte Zafar, Muhammad Nadeem Mohamed Ibrahim Halawa Han, Shuang Zhang, Wei Xu, Guobao |
| description | A new chemiluminescence (CL) system, indigo carmine/glucose/hemin/H2O2, has been found and developed for non-enzymatic detection of indigo carmine (IC) and glucose. The CL response increases linearly with IC concentrations from 3.2 μM to 10 mM and glucose concentrations from 0.06 μM to 3.5 mM. The detection limits are 1.45 μM and 15.0 nM for IC and glucose, respectively. This method allows the determination of glucose in blood and urine after simple dilution. The recoveries for the determination of glucose are between 98.5% and 101.0% in blood and between 98.5% and 101.3% in urine. This method shows good sensitivity, selectivity, simplicity, and is low cost, suggesting its promising broad applications. |
| doi_str_mv | 10.1039/c9an02100k |
| format | Article |
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The CL response increases linearly with IC concentrations from 3.2 μM to 10 mM and glucose concentrations from 0.06 μM to 3.5 mM. The detection limits are 1.45 μM and 15.0 nM for IC and glucose, respectively. This method allows the determination of glucose in blood and urine after simple dilution. The recoveries for the determination of glucose are between 98.5% and 101.0% in blood and between 98.5% and 101.3% in urine. This method shows good sensitivity, selectivity, simplicity, and is low cost, suggesting its promising broad applications.</description><identifier>ISSN: 0003-2654</identifier><identifier>EISSN: 1364-5528</identifier><identifier>DOI: 10.1039/c9an02100k</identifier><language>eng</language><publisher>London: Royal Society of Chemistry</publisher><subject>Blood ; Chemiluminescence ; Dilution ; Glucose ; Hydrogen peroxide ; Indigo ; Organic chemistry ; Selectivity ; Urine</subject><ispartof>Analyst (London), 2020-02, Vol.145 (3), p.1041-1046</ispartof><rights>Copyright Royal Society of Chemistry 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Tadesse Haile Fereja</creatorcontrib><creatorcontrib>Shimeles Addisu Kitte</creatorcontrib><creatorcontrib>Zafar, Muhammad Nadeem</creatorcontrib><creatorcontrib>Mohamed Ibrahim Halawa</creatorcontrib><creatorcontrib>Han, Shuang</creatorcontrib><creatorcontrib>Zhang, Wei</creatorcontrib><creatorcontrib>Xu, Guobao</creatorcontrib><title>Highly sensitive and selective non-enzymatic glucose detection based on indigo carmine/hemin/H2O2 chemiluminescence</title><title>Analyst (London)</title><description>A new chemiluminescence (CL) system, indigo carmine/glucose/hemin/H2O2, has been found and developed for non-enzymatic detection of indigo carmine (IC) and glucose. The CL response increases linearly with IC concentrations from 3.2 μM to 10 mM and glucose concentrations from 0.06 μM to 3.5 mM. The detection limits are 1.45 μM and 15.0 nM for IC and glucose, respectively. This method allows the determination of glucose in blood and urine after simple dilution. The recoveries for the determination of glucose are between 98.5% and 101.0% in blood and between 98.5% and 101.3% in urine. This method shows good sensitivity, selectivity, simplicity, and is low cost, suggesting its promising broad applications.</description><subject>Blood</subject><subject>Chemiluminescence</subject><subject>Dilution</subject><subject>Glucose</subject><subject>Hydrogen peroxide</subject><subject>Indigo</subject><subject>Organic chemistry</subject><subject>Selectivity</subject><subject>Urine</subject><issn>0003-2654</issn><issn>1364-5528</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNpdjr1OwzAUhS0EEqWw8ASWWFhCr-3EcUZUQYtUqQvMlWPftC6uXeoEqTw9LjAxnZ_76eoQcsvggYFoJqbRATgDeD8jIyZkWVQVV-dkBACi4LIqL8lVStscGVQwImnu1ht_pAlDcr37RKqDzcmj-UkhhgLD13Gne2fo2g8mJqQW-9M9BtrqhJZm44J160iNPuxcwMkGs0zmfMmpOXk_nOpkMBi8Jhed9glv_nRM3p6fXqfzYrGcvUwfF8WeM9kXHKWtpcK6Q1TYttjWBhjvtCnBouAlSi4AO6G60gqljbEmQ7brSiObBsWY3P_-3R_ix4CpX-1cXuC9DhiHtOKC103JoOYZvfuHbuNwCHldpipQqm6EFN8EQm29</recordid><startdate>20200207</startdate><enddate>20200207</enddate><creator>Tadesse Haile Fereja</creator><creator>Shimeles Addisu Kitte</creator><creator>Zafar, Muhammad Nadeem</creator><creator>Mohamed Ibrahim Halawa</creator><creator>Han, Shuang</creator><creator>Zhang, Wei</creator><creator>Xu, Guobao</creator><general>Royal Society of Chemistry</general><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope><scope>7X8</scope></search><sort><creationdate>20200207</creationdate><title>Highly sensitive and selective non-enzymatic glucose detection based on indigo carmine/hemin/H2O2 chemiluminescence</title><author>Tadesse Haile Fereja ; Shimeles Addisu Kitte ; Zafar, Muhammad Nadeem ; Mohamed Ibrahim Halawa ; Han, Shuang ; Zhang, Wei ; Xu, Guobao</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p216t-2e6d768e7fee8ebbeb7c012fac40de324e6230ef38f4d38accdcbebdff4c699e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Blood</topic><topic>Chemiluminescence</topic><topic>Dilution</topic><topic>Glucose</topic><topic>Hydrogen peroxide</topic><topic>Indigo</topic><topic>Organic chemistry</topic><topic>Selectivity</topic><topic>Urine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tadesse Haile Fereja</creatorcontrib><creatorcontrib>Shimeles Addisu Kitte</creatorcontrib><creatorcontrib>Zafar, Muhammad Nadeem</creatorcontrib><creatorcontrib>Mohamed Ibrahim Halawa</creatorcontrib><creatorcontrib>Han, Shuang</creatorcontrib><creatorcontrib>Zhang, Wei</creatorcontrib><creatorcontrib>Xu, Guobao</creatorcontrib><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Analyst (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tadesse Haile Fereja</au><au>Shimeles Addisu Kitte</au><au>Zafar, Muhammad Nadeem</au><au>Mohamed Ibrahim Halawa</au><au>Han, Shuang</au><au>Zhang, Wei</au><au>Xu, Guobao</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Highly sensitive and selective non-enzymatic glucose detection based on indigo carmine/hemin/H2O2 chemiluminescence</atitle><jtitle>Analyst (London)</jtitle><date>2020-02-07</date><risdate>2020</risdate><volume>145</volume><issue>3</issue><spage>1041</spage><epage>1046</epage><pages>1041-1046</pages><issn>0003-2654</issn><eissn>1364-5528</eissn><abstract>A new chemiluminescence (CL) system, indigo carmine/glucose/hemin/H2O2, has been found and developed for non-enzymatic detection of indigo carmine (IC) and glucose. 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| source | Royal Society of Chemistry Journals Archive (1841-2007); Alma/SFX Local Collection; Royal Society of Chemistry E-Journals |
| subjects | Blood Chemiluminescence Dilution Glucose Hydrogen peroxide Indigo Organic chemistry Selectivity Urine |
| title | Highly sensitive and selective non-enzymatic glucose detection based on indigo carmine/hemin/H2O2 chemiluminescence |
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