The Impact of Peripheral Artery Disease in Chronic Total Occlusion Percutaneous Coronary Intervention (Insights From PROGRESS-CTO Registry)

The impact of peripheral artery disease (PAD) in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study. We reviewed 3999 CTO PCIs performed in 3914 patients between 2012 and 2018 at 25 centers, 14% of whom had a history of PAD. We compa...

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Veröffentlicht in:Angiology 2020-03, Vol.71 (3), p.274-280
Hauptverfasser: Xenogiannis, Iosif, Gkargkoulas, Fotis, Karmpaliotis, Dimitri, Alaswad, Khaldoon, Krestyaninov, Oleg, Khelimskii, Dmitrii, Choi, James W., Jaffer, Farouc A., Patel, Mitul, Mahmud, Ehtisham, Khatri, Jaikirshan J., Kandzari, David E., Doing, Anthony H., Dattilo, Phil, Toma, Catalin, Koutouzis, Michalis, Tsiafoutis, Ioannis, Uretsky, Barry, Yeh, Robert W., Tamez, Hector, Wyman, R. Michael, Jefferson, Brian K., Patel, Taral, Jaber, Wissam, Samady, Habib, Sheikh, Abdul M., Malik, Bilal A., Holper, Elizabeth, Potluri, Srinivasa, Moses, Jeffrey W., Lembo, Nicholas J., Parikh, Manish, Kirtane, Ajay J., Ali, Ziad A., Hall, Allison B., Vemmou, Evangelia, Nikolakopoulos, Ilias, Dargham, Bassel Bou, Rangan, Bavana V., Abdullah, Shuaib, Garcia, Santiago, Banerjee, Subhash, Burke, M. Nicholas, Brilakis, Emmanouil S.
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container_end_page 280
container_issue 3
container_start_page 274
container_title Angiology
container_volume 71
creator Xenogiannis, Iosif
Gkargkoulas, Fotis
Karmpaliotis, Dimitri
Alaswad, Khaldoon
Krestyaninov, Oleg
Khelimskii, Dmitrii
Choi, James W.
Jaffer, Farouc A.
Patel, Mitul
Mahmud, Ehtisham
Khatri, Jaikirshan J.
Kandzari, David E.
Doing, Anthony H.
Dattilo, Phil
Toma, Catalin
Koutouzis, Michalis
Tsiafoutis, Ioannis
Uretsky, Barry
Yeh, Robert W.
Tamez, Hector
Wyman, R. Michael
Jefferson, Brian K.
Patel, Taral
Jaber, Wissam
Samady, Habib
Sheikh, Abdul M.
Malik, Bilal A.
Holper, Elizabeth
Potluri, Srinivasa
Moses, Jeffrey W.
Lembo, Nicholas J.
Parikh, Manish
Kirtane, Ajay J.
Ali, Ziad A.
Hall, Allison B.
Vemmou, Evangelia
Nikolakopoulos, Ilias
Dargham, Bassel Bou
Rangan, Bavana V.
Abdullah, Shuaib
Garcia, Santiago
Banerjee, Subhash
Burke, M. Nicholas
Brilakis, Emmanouil S.
description The impact of peripheral artery disease (PAD) in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study. We reviewed 3999 CTO PCIs performed in 3914 patients between 2012 and 2018 at 25 centers, 14% of whom had a history of PAD. We compared the clinical and angiographic characteristics and procedural outcomes of patients with versus without history of PAD. Patients with PAD were older (67 ± 9 vs 64 ± 10 years, P < .001) and had a higher prevalence of cardiovascular risk factors. They also had more complex lesions as illustrated by higher Japanese CTO score (2.7 ± 1.2 vs 2.4 ± 1.3, P < .001). In patients with PAD, the final crossing technique was less often antegrade wire escalation (40% vs 51%, P < .001) and more often the retrograde approach (23 vs 20%, P < .001) and antegrade dissection/reentry (20% vs 16%, P < .001). Technical success was similar between the 2 study groups (84% vs 87%, P = .127), but procedural success was lower for patients with PAD (81% vs 85%, P = .015). The incidence of in-hospital major adverse cardiac events was higher among patients with PAD (3% vs 2%, P = .046). In conclusion, patients with PAD undergoing CTO PCI have more comorbidities, more complex lesions, and lower procedural success.
doi_str_mv 10.1177/0003319719895178
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Michael ; Jefferson, Brian K. ; Patel, Taral ; Jaber, Wissam ; Samady, Habib ; Sheikh, Abdul M. ; Malik, Bilal A. ; Holper, Elizabeth ; Potluri, Srinivasa ; Moses, Jeffrey W. ; Lembo, Nicholas J. ; Parikh, Manish ; Kirtane, Ajay J. ; Ali, Ziad A. ; Hall, Allison B. ; Vemmou, Evangelia ; Nikolakopoulos, Ilias ; Dargham, Bassel Bou ; Rangan, Bavana V. ; Abdullah, Shuaib ; Garcia, Santiago ; Banerjee, Subhash ; Burke, M. Nicholas ; Brilakis, Emmanouil S.</creator><creatorcontrib>Xenogiannis, Iosif ; Gkargkoulas, Fotis ; Karmpaliotis, Dimitri ; Alaswad, Khaldoon ; Krestyaninov, Oleg ; Khelimskii, Dmitrii ; Choi, James W. ; Jaffer, Farouc A. ; Patel, Mitul ; Mahmud, Ehtisham ; Khatri, Jaikirshan J. ; Kandzari, David E. ; Doing, Anthony H. ; Dattilo, Phil ; Toma, Catalin ; Koutouzis, Michalis ; Tsiafoutis, Ioannis ; Uretsky, Barry ; Yeh, Robert W. ; Tamez, Hector ; Wyman, R. Michael ; Jefferson, Brian K. ; Patel, Taral ; Jaber, Wissam ; Samady, Habib ; Sheikh, Abdul M. ; Malik, Bilal A. ; Holper, Elizabeth ; Potluri, Srinivasa ; Moses, Jeffrey W. ; Lembo, Nicholas J. ; Parikh, Manish ; Kirtane, Ajay J. ; Ali, Ziad A. ; Hall, Allison B. ; Vemmou, Evangelia ; Nikolakopoulos, Ilias ; Dargham, Bassel Bou ; Rangan, Bavana V. ; Abdullah, Shuaib ; Garcia, Santiago ; Banerjee, Subhash ; Burke, M. Nicholas ; Brilakis, Emmanouil S.</creatorcontrib><description>The impact of peripheral artery disease (PAD) in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study. We reviewed 3999 CTO PCIs performed in 3914 patients between 2012 and 2018 at 25 centers, 14% of whom had a history of PAD. We compared the clinical and angiographic characteristics and procedural outcomes of patients with versus without history of PAD. Patients with PAD were older (67 ± 9 vs 64 ± 10 years, P &lt; .001) and had a higher prevalence of cardiovascular risk factors. They also had more complex lesions as illustrated by higher Japanese CTO score (2.7 ± 1.2 vs 2.4 ± 1.3, P &lt; .001). In patients with PAD, the final crossing technique was less often antegrade wire escalation (40% vs 51%, P &lt; .001) and more often the retrograde approach (23 vs 20%, P &lt; .001) and antegrade dissection/reentry (20% vs 16%, P &lt; .001). Technical success was similar between the 2 study groups (84% vs 87%, P = .127), but procedural success was lower for patients with PAD (81% vs 85%, P = .015). The incidence of in-hospital major adverse cardiac events was higher among patients with PAD (3% vs 2%, P = .046). 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Nicholas</creatorcontrib><creatorcontrib>Brilakis, Emmanouil S.</creatorcontrib><title>The Impact of Peripheral Artery Disease in Chronic Total Occlusion Percutaneous Coronary Intervention (Insights From PROGRESS-CTO Registry)</title><title>Angiology</title><addtitle>Angiology</addtitle><description>The impact of peripheral artery disease (PAD) in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study. We reviewed 3999 CTO PCIs performed in 3914 patients between 2012 and 2018 at 25 centers, 14% of whom had a history of PAD. We compared the clinical and angiographic characteristics and procedural outcomes of patients with versus without history of PAD. Patients with PAD were older (67 ± 9 vs 64 ± 10 years, P &lt; .001) and had a higher prevalence of cardiovascular risk factors. They also had more complex lesions as illustrated by higher Japanese CTO score (2.7 ± 1.2 vs 2.4 ± 1.3, P &lt; .001). In patients with PAD, the final crossing technique was less often antegrade wire escalation (40% vs 51%, P &lt; .001) and more often the retrograde approach (23 vs 20%, P &lt; .001) and antegrade dissection/reentry (20% vs 16%, P &lt; .001). Technical success was similar between the 2 study groups (84% vs 87%, P = .127), but procedural success was lower for patients with PAD (81% vs 85%, P = .015). The incidence of in-hospital major adverse cardiac events was higher among patients with PAD (3% vs 2%, P = .046). In conclusion, patients with PAD undergoing CTO PCI have more comorbidities, more complex lesions, and lower procedural success.</description><subject>Adult</subject><subject>Aged</subject><subject>Chronic Disease</subject><subject>Coronary Angiography - methods</subject><subject>Coronary Occlusion - complications</subject><subject>Coronary Occlusion - diagnostic imaging</subject><subject>Coronary Occlusion - therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Percutaneous Coronary Intervention - methods</subject><subject>Peripheral Arterial Disease - complications</subject><subject>Peripheral Arterial Disease - surgery</subject><subject>Registries</subject><subject>Risk Factors</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>0003-3197</issn><issn>1940-1574</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kV1LwzAUhoMoOj_uvZJc6kU1WdoluZT6NRA2Zu9Llp5ukbaZSSrsN_inTdn0QvAqhPd5XjjnIHRJyS2lnN8RQhijklMpZEa5OEAjKlOS0Iynh2g0xMmQn6BT79_jN6NkcoxOGBVplkk2Ql_FGvC03SgdsK3xHJzZrMGpBt-7AG6LH4wH5QGbDudrZzujcWFDzGdaN703thsk3QfVge09zm2EVBSnXfQ_oQsDcj3tvFmtg8dPzrZ4vpg9Lx7f3pK8mOEFrIwPbntzjo5q1Xi42L9nqHh6LPKX5HX2PM3vXxPNGA9JLdlkzLO0UpoqKoiiVcX1REGdgZCS1ZXKalimWnBai1SlYy7JMhVMUs6WFTtD17vajbMfPfhQtsZraJrdBOWYRYEJIcYRJTtUO-u9g7rcONPG6UpKyuEC5d8LROVq394vW6h-hZ-VRyDZAV6toHy3vevisP8XfgNmMY6k</recordid><startdate>202003</startdate><enddate>202003</enddate><creator>Xenogiannis, Iosif</creator><creator>Gkargkoulas, Fotis</creator><creator>Karmpaliotis, Dimitri</creator><creator>Alaswad, Khaldoon</creator><creator>Krestyaninov, Oleg</creator><creator>Khelimskii, Dmitrii</creator><creator>Choi, James W.</creator><creator>Jaffer, Farouc A.</creator><creator>Patel, Mitul</creator><creator>Mahmud, Ehtisham</creator><creator>Khatri, Jaikirshan J.</creator><creator>Kandzari, David E.</creator><creator>Doing, Anthony H.</creator><creator>Dattilo, Phil</creator><creator>Toma, Catalin</creator><creator>Koutouzis, Michalis</creator><creator>Tsiafoutis, Ioannis</creator><creator>Uretsky, Barry</creator><creator>Yeh, Robert W.</creator><creator>Tamez, Hector</creator><creator>Wyman, R. 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Michael ; Jefferson, Brian K. ; Patel, Taral ; Jaber, Wissam ; Samady, Habib ; Sheikh, Abdul M. ; Malik, Bilal A. ; Holper, Elizabeth ; Potluri, Srinivasa ; Moses, Jeffrey W. ; Lembo, Nicholas J. ; Parikh, Manish ; Kirtane, Ajay J. ; Ali, Ziad A. ; Hall, Allison B. ; Vemmou, Evangelia ; Nikolakopoulos, Ilias ; Dargham, Bassel Bou ; Rangan, Bavana V. ; Abdullah, Shuaib ; Garcia, Santiago ; Banerjee, Subhash ; Burke, M. 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Nicholas</creatorcontrib><creatorcontrib>Brilakis, Emmanouil S.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Angiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Xenogiannis, Iosif</au><au>Gkargkoulas, Fotis</au><au>Karmpaliotis, Dimitri</au><au>Alaswad, Khaldoon</au><au>Krestyaninov, Oleg</au><au>Khelimskii, Dmitrii</au><au>Choi, James W.</au><au>Jaffer, Farouc A.</au><au>Patel, Mitul</au><au>Mahmud, Ehtisham</au><au>Khatri, Jaikirshan J.</au><au>Kandzari, David E.</au><au>Doing, Anthony H.</au><au>Dattilo, Phil</au><au>Toma, Catalin</au><au>Koutouzis, Michalis</au><au>Tsiafoutis, Ioannis</au><au>Uretsky, Barry</au><au>Yeh, Robert W.</au><au>Tamez, Hector</au><au>Wyman, R. Michael</au><au>Jefferson, Brian K.</au><au>Patel, Taral</au><au>Jaber, Wissam</au><au>Samady, Habib</au><au>Sheikh, Abdul M.</au><au>Malik, Bilal A.</au><au>Holper, Elizabeth</au><au>Potluri, Srinivasa</au><au>Moses, Jeffrey W.</au><au>Lembo, Nicholas J.</au><au>Parikh, Manish</au><au>Kirtane, Ajay J.</au><au>Ali, Ziad A.</au><au>Hall, Allison B.</au><au>Vemmou, Evangelia</au><au>Nikolakopoulos, Ilias</au><au>Dargham, Bassel Bou</au><au>Rangan, Bavana V.</au><au>Abdullah, Shuaib</au><au>Garcia, Santiago</au><au>Banerjee, Subhash</au><au>Burke, M. Nicholas</au><au>Brilakis, Emmanouil S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Impact of Peripheral Artery Disease in Chronic Total Occlusion Percutaneous Coronary Intervention (Insights From PROGRESS-CTO Registry)</atitle><jtitle>Angiology</jtitle><addtitle>Angiology</addtitle><date>2020-03</date><risdate>2020</risdate><volume>71</volume><issue>3</issue><spage>274</spage><epage>280</epage><pages>274-280</pages><issn>0003-3197</issn><eissn>1940-1574</eissn><abstract>The impact of peripheral artery disease (PAD) in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study. We reviewed 3999 CTO PCIs performed in 3914 patients between 2012 and 2018 at 25 centers, 14% of whom had a history of PAD. We compared the clinical and angiographic characteristics and procedural outcomes of patients with versus without history of PAD. Patients with PAD were older (67 ± 9 vs 64 ± 10 years, P &lt; .001) and had a higher prevalence of cardiovascular risk factors. They also had more complex lesions as illustrated by higher Japanese CTO score (2.7 ± 1.2 vs 2.4 ± 1.3, P &lt; .001). In patients with PAD, the final crossing technique was less often antegrade wire escalation (40% vs 51%, P &lt; .001) and more often the retrograde approach (23 vs 20%, P &lt; .001) and antegrade dissection/reentry (20% vs 16%, P &lt; .001). Technical success was similar between the 2 study groups (84% vs 87%, P = .127), but procedural success was lower for patients with PAD (81% vs 85%, P = .015). The incidence of in-hospital major adverse cardiac events was higher among patients with PAD (3% vs 2%, P = .046). In conclusion, patients with PAD undergoing CTO PCI have more comorbidities, more complex lesions, and lower procedural success.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>31845593</pmid><doi>10.1177/0003319719895178</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-9416-9701</orcidid><orcidid>https://orcid.org/0000-0002-5004-6635</orcidid></addata></record>
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identifier ISSN: 0003-3197
ispartof Angiology, 2020-03, Vol.71 (3), p.274-280
issn 0003-3197
1940-1574
language eng
recordid cdi_proquest_miscellaneous_2327938882
source Access via SAGE; MEDLINE
subjects Adult
Aged
Chronic Disease
Coronary Angiography - methods
Coronary Occlusion - complications
Coronary Occlusion - diagnostic imaging
Coronary Occlusion - therapy
Female
Humans
Male
Middle Aged
Percutaneous Coronary Intervention - methods
Peripheral Arterial Disease - complications
Peripheral Arterial Disease - surgery
Registries
Risk Factors
Time Factors
Treatment Outcome
title The Impact of Peripheral Artery Disease in Chronic Total Occlusion Percutaneous Coronary Intervention (Insights From PROGRESS-CTO Registry)
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