The Impact of Peripheral Artery Disease in Chronic Total Occlusion Percutaneous Coronary Intervention (Insights From PROGRESS-CTO Registry)
The impact of peripheral artery disease (PAD) in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study. We reviewed 3999 CTO PCIs performed in 3914 patients between 2012 and 2018 at 25 centers, 14% of whom had a history of PAD. We compa...
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Veröffentlicht in: | Angiology 2020-03, Vol.71 (3), p.274-280 |
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creator | Xenogiannis, Iosif Gkargkoulas, Fotis Karmpaliotis, Dimitri Alaswad, Khaldoon Krestyaninov, Oleg Khelimskii, Dmitrii Choi, James W. Jaffer, Farouc A. Patel, Mitul Mahmud, Ehtisham Khatri, Jaikirshan J. Kandzari, David E. Doing, Anthony H. Dattilo, Phil Toma, Catalin Koutouzis, Michalis Tsiafoutis, Ioannis Uretsky, Barry Yeh, Robert W. Tamez, Hector Wyman, R. Michael Jefferson, Brian K. Patel, Taral Jaber, Wissam Samady, Habib Sheikh, Abdul M. Malik, Bilal A. Holper, Elizabeth Potluri, Srinivasa Moses, Jeffrey W. Lembo, Nicholas J. Parikh, Manish Kirtane, Ajay J. Ali, Ziad A. Hall, Allison B. Vemmou, Evangelia Nikolakopoulos, Ilias Dargham, Bassel Bou Rangan, Bavana V. Abdullah, Shuaib Garcia, Santiago Banerjee, Subhash Burke, M. Nicholas Brilakis, Emmanouil S. |
description | The impact of peripheral artery disease (PAD) in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study. We reviewed 3999 CTO PCIs performed in 3914 patients between 2012 and 2018 at 25 centers, 14% of whom had a history of PAD. We compared the clinical and angiographic characteristics and procedural outcomes of patients with versus without history of PAD. Patients with PAD were older (67 ± 9 vs 64 ± 10 years, P < .001) and had a higher prevalence of cardiovascular risk factors. They also had more complex lesions as illustrated by higher Japanese CTO score (2.7 ± 1.2 vs 2.4 ± 1.3, P < .001). In patients with PAD, the final crossing technique was less often antegrade wire escalation (40% vs 51%, P < .001) and more often the retrograde approach (23 vs 20%, P < .001) and antegrade dissection/reentry (20% vs 16%, P < .001). Technical success was similar between the 2 study groups (84% vs 87%, P = .127), but procedural success was lower for patients with PAD (81% vs 85%, P = .015). The incidence of in-hospital major adverse cardiac events was higher among patients with PAD (3% vs 2%, P = .046). In conclusion, patients with PAD undergoing CTO PCI have more comorbidities, more complex lesions, and lower procedural success. |
doi_str_mv | 10.1177/0003319719895178 |
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Michael ; Jefferson, Brian K. ; Patel, Taral ; Jaber, Wissam ; Samady, Habib ; Sheikh, Abdul M. ; Malik, Bilal A. ; Holper, Elizabeth ; Potluri, Srinivasa ; Moses, Jeffrey W. ; Lembo, Nicholas J. ; Parikh, Manish ; Kirtane, Ajay J. ; Ali, Ziad A. ; Hall, Allison B. ; Vemmou, Evangelia ; Nikolakopoulos, Ilias ; Dargham, Bassel Bou ; Rangan, Bavana V. ; Abdullah, Shuaib ; Garcia, Santiago ; Banerjee, Subhash ; Burke, M. Nicholas ; Brilakis, Emmanouil S.</creator><creatorcontrib>Xenogiannis, Iosif ; Gkargkoulas, Fotis ; Karmpaliotis, Dimitri ; Alaswad, Khaldoon ; Krestyaninov, Oleg ; Khelimskii, Dmitrii ; Choi, James W. ; Jaffer, Farouc A. ; Patel, Mitul ; Mahmud, Ehtisham ; Khatri, Jaikirshan J. ; Kandzari, David E. ; Doing, Anthony H. ; Dattilo, Phil ; Toma, Catalin ; Koutouzis, Michalis ; Tsiafoutis, Ioannis ; Uretsky, Barry ; Yeh, Robert W. ; Tamez, Hector ; Wyman, R. Michael ; Jefferson, Brian K. ; Patel, Taral ; Jaber, Wissam ; Samady, Habib ; Sheikh, Abdul M. ; Malik, Bilal A. ; Holper, Elizabeth ; Potluri, Srinivasa ; Moses, Jeffrey W. ; Lembo, Nicholas J. ; Parikh, Manish ; Kirtane, Ajay J. ; Ali, Ziad A. ; Hall, Allison B. ; Vemmou, Evangelia ; Nikolakopoulos, Ilias ; Dargham, Bassel Bou ; Rangan, Bavana V. ; Abdullah, Shuaib ; Garcia, Santiago ; Banerjee, Subhash ; Burke, M. Nicholas ; Brilakis, Emmanouil S.</creatorcontrib><description>The impact of peripheral artery disease (PAD) in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study. We reviewed 3999 CTO PCIs performed in 3914 patients between 2012 and 2018 at 25 centers, 14% of whom had a history of PAD. We compared the clinical and angiographic characteristics and procedural outcomes of patients with versus without history of PAD. Patients with PAD were older (67 ± 9 vs 64 ± 10 years, P < .001) and had a higher prevalence of cardiovascular risk factors. They also had more complex lesions as illustrated by higher Japanese CTO score (2.7 ± 1.2 vs 2.4 ± 1.3, P < .001). In patients with PAD, the final crossing technique was less often antegrade wire escalation (40% vs 51%, P < .001) and more often the retrograde approach (23 vs 20%, P < .001) and antegrade dissection/reentry (20% vs 16%, P < .001). Technical success was similar between the 2 study groups (84% vs 87%, P = .127), but procedural success was lower for patients with PAD (81% vs 85%, P = .015). The incidence of in-hospital major adverse cardiac events was higher among patients with PAD (3% vs 2%, P = .046). In conclusion, patients with PAD undergoing CTO PCI have more comorbidities, more complex lesions, and lower procedural success.</description><identifier>ISSN: 0003-3197</identifier><identifier>EISSN: 1940-1574</identifier><identifier>DOI: 10.1177/0003319719895178</identifier><identifier>PMID: 31845593</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Adult ; Aged ; Chronic Disease ; Coronary Angiography - methods ; Coronary Occlusion - complications ; Coronary Occlusion - diagnostic imaging ; Coronary Occlusion - therapy ; Female ; Humans ; Male ; Middle Aged ; Percutaneous Coronary Intervention - methods ; Peripheral Arterial Disease - complications ; Peripheral Arterial Disease - surgery ; Registries ; Risk Factors ; Time Factors ; Treatment Outcome</subject><ispartof>Angiology, 2020-03, Vol.71 (3), p.274-280</ispartof><rights>The Author(s) 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c337t-f9362754dac1a180a1dd7c6aef5e8993fda5feb4c871f84a42790b4839173bd3</citedby><cites>FETCH-LOGICAL-c337t-f9362754dac1a180a1dd7c6aef5e8993fda5feb4c871f84a42790b4839173bd3</cites><orcidid>0000-0001-9416-9701 ; 0000-0002-5004-6635</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/0003319719895178$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/0003319719895178$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,21819,27924,27925,43621,43622</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31845593$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Xenogiannis, Iosif</creatorcontrib><creatorcontrib>Gkargkoulas, Fotis</creatorcontrib><creatorcontrib>Karmpaliotis, Dimitri</creatorcontrib><creatorcontrib>Alaswad, Khaldoon</creatorcontrib><creatorcontrib>Krestyaninov, Oleg</creatorcontrib><creatorcontrib>Khelimskii, Dmitrii</creatorcontrib><creatorcontrib>Choi, James W.</creatorcontrib><creatorcontrib>Jaffer, Farouc A.</creatorcontrib><creatorcontrib>Patel, Mitul</creatorcontrib><creatorcontrib>Mahmud, Ehtisham</creatorcontrib><creatorcontrib>Khatri, Jaikirshan J.</creatorcontrib><creatorcontrib>Kandzari, David E.</creatorcontrib><creatorcontrib>Doing, Anthony H.</creatorcontrib><creatorcontrib>Dattilo, Phil</creatorcontrib><creatorcontrib>Toma, Catalin</creatorcontrib><creatorcontrib>Koutouzis, Michalis</creatorcontrib><creatorcontrib>Tsiafoutis, Ioannis</creatorcontrib><creatorcontrib>Uretsky, Barry</creatorcontrib><creatorcontrib>Yeh, Robert W.</creatorcontrib><creatorcontrib>Tamez, Hector</creatorcontrib><creatorcontrib>Wyman, R. Michael</creatorcontrib><creatorcontrib>Jefferson, Brian K.</creatorcontrib><creatorcontrib>Patel, Taral</creatorcontrib><creatorcontrib>Jaber, Wissam</creatorcontrib><creatorcontrib>Samady, Habib</creatorcontrib><creatorcontrib>Sheikh, Abdul M.</creatorcontrib><creatorcontrib>Malik, Bilal A.</creatorcontrib><creatorcontrib>Holper, Elizabeth</creatorcontrib><creatorcontrib>Potluri, Srinivasa</creatorcontrib><creatorcontrib>Moses, Jeffrey W.</creatorcontrib><creatorcontrib>Lembo, Nicholas J.</creatorcontrib><creatorcontrib>Parikh, Manish</creatorcontrib><creatorcontrib>Kirtane, Ajay J.</creatorcontrib><creatorcontrib>Ali, Ziad A.</creatorcontrib><creatorcontrib>Hall, Allison B.</creatorcontrib><creatorcontrib>Vemmou, Evangelia</creatorcontrib><creatorcontrib>Nikolakopoulos, Ilias</creatorcontrib><creatorcontrib>Dargham, Bassel Bou</creatorcontrib><creatorcontrib>Rangan, Bavana V.</creatorcontrib><creatorcontrib>Abdullah, Shuaib</creatorcontrib><creatorcontrib>Garcia, Santiago</creatorcontrib><creatorcontrib>Banerjee, Subhash</creatorcontrib><creatorcontrib>Burke, M. Nicholas</creatorcontrib><creatorcontrib>Brilakis, Emmanouil S.</creatorcontrib><title>The Impact of Peripheral Artery Disease in Chronic Total Occlusion Percutaneous Coronary Intervention (Insights From PROGRESS-CTO Registry)</title><title>Angiology</title><addtitle>Angiology</addtitle><description>The impact of peripheral artery disease (PAD) in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study. We reviewed 3999 CTO PCIs performed in 3914 patients between 2012 and 2018 at 25 centers, 14% of whom had a history of PAD. We compared the clinical and angiographic characteristics and procedural outcomes of patients with versus without history of PAD. Patients with PAD were older (67 ± 9 vs 64 ± 10 years, P < .001) and had a higher prevalence of cardiovascular risk factors. They also had more complex lesions as illustrated by higher Japanese CTO score (2.7 ± 1.2 vs 2.4 ± 1.3, P < .001). In patients with PAD, the final crossing technique was less often antegrade wire escalation (40% vs 51%, P < .001) and more often the retrograde approach (23 vs 20%, P < .001) and antegrade dissection/reentry (20% vs 16%, P < .001). Technical success was similar between the 2 study groups (84% vs 87%, P = .127), but procedural success was lower for patients with PAD (81% vs 85%, P = .015). The incidence of in-hospital major adverse cardiac events was higher among patients with PAD (3% vs 2%, P = .046). In conclusion, patients with PAD undergoing CTO PCI have more comorbidities, more complex lesions, and lower procedural success.</description><subject>Adult</subject><subject>Aged</subject><subject>Chronic Disease</subject><subject>Coronary Angiography - methods</subject><subject>Coronary Occlusion - complications</subject><subject>Coronary Occlusion - diagnostic imaging</subject><subject>Coronary Occlusion - therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Percutaneous Coronary Intervention - methods</subject><subject>Peripheral Arterial Disease - complications</subject><subject>Peripheral Arterial Disease - surgery</subject><subject>Registries</subject><subject>Risk Factors</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>0003-3197</issn><issn>1940-1574</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kV1LwzAUhoMoOj_uvZJc6kU1WdoluZT6NRA2Zu9Llp5ukbaZSSrsN_inTdn0QvAqhPd5XjjnIHRJyS2lnN8RQhijklMpZEa5OEAjKlOS0Iynh2g0xMmQn6BT79_jN6NkcoxOGBVplkk2Ql_FGvC03SgdsK3xHJzZrMGpBt-7AG6LH4wH5QGbDudrZzujcWFDzGdaN703thsk3QfVge09zm2EVBSnXfQ_oQsDcj3tvFmtg8dPzrZ4vpg9Lx7f3pK8mOEFrIwPbntzjo5q1Xi42L9nqHh6LPKX5HX2PM3vXxPNGA9JLdlkzLO0UpoqKoiiVcX1REGdgZCS1ZXKalimWnBai1SlYy7JMhVMUs6WFTtD17vajbMfPfhQtsZraJrdBOWYRYEJIcYRJTtUO-u9g7rcONPG6UpKyuEC5d8LROVq394vW6h-hZ-VRyDZAV6toHy3vevisP8XfgNmMY6k</recordid><startdate>202003</startdate><enddate>202003</enddate><creator>Xenogiannis, Iosif</creator><creator>Gkargkoulas, Fotis</creator><creator>Karmpaliotis, Dimitri</creator><creator>Alaswad, Khaldoon</creator><creator>Krestyaninov, Oleg</creator><creator>Khelimskii, Dmitrii</creator><creator>Choi, James W.</creator><creator>Jaffer, Farouc A.</creator><creator>Patel, Mitul</creator><creator>Mahmud, Ehtisham</creator><creator>Khatri, Jaikirshan J.</creator><creator>Kandzari, David E.</creator><creator>Doing, Anthony H.</creator><creator>Dattilo, Phil</creator><creator>Toma, Catalin</creator><creator>Koutouzis, Michalis</creator><creator>Tsiafoutis, Ioannis</creator><creator>Uretsky, Barry</creator><creator>Yeh, Robert W.</creator><creator>Tamez, Hector</creator><creator>Wyman, R. 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Michael ; Jefferson, Brian K. ; Patel, Taral ; Jaber, Wissam ; Samady, Habib ; Sheikh, Abdul M. ; Malik, Bilal A. ; Holper, Elizabeth ; Potluri, Srinivasa ; Moses, Jeffrey W. ; Lembo, Nicholas J. ; Parikh, Manish ; Kirtane, Ajay J. ; Ali, Ziad A. ; Hall, Allison B. ; Vemmou, Evangelia ; Nikolakopoulos, Ilias ; Dargham, Bassel Bou ; Rangan, Bavana V. ; Abdullah, Shuaib ; Garcia, Santiago ; Banerjee, Subhash ; Burke, M. 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Michael</au><au>Jefferson, Brian K.</au><au>Patel, Taral</au><au>Jaber, Wissam</au><au>Samady, Habib</au><au>Sheikh, Abdul M.</au><au>Malik, Bilal A.</au><au>Holper, Elizabeth</au><au>Potluri, Srinivasa</au><au>Moses, Jeffrey W.</au><au>Lembo, Nicholas J.</au><au>Parikh, Manish</au><au>Kirtane, Ajay J.</au><au>Ali, Ziad A.</au><au>Hall, Allison B.</au><au>Vemmou, Evangelia</au><au>Nikolakopoulos, Ilias</au><au>Dargham, Bassel Bou</au><au>Rangan, Bavana V.</au><au>Abdullah, Shuaib</au><au>Garcia, Santiago</au><au>Banerjee, Subhash</au><au>Burke, M. Nicholas</au><au>Brilakis, Emmanouil S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Impact of Peripheral Artery Disease in Chronic Total Occlusion Percutaneous Coronary Intervention (Insights From PROGRESS-CTO Registry)</atitle><jtitle>Angiology</jtitle><addtitle>Angiology</addtitle><date>2020-03</date><risdate>2020</risdate><volume>71</volume><issue>3</issue><spage>274</spage><epage>280</epage><pages>274-280</pages><issn>0003-3197</issn><eissn>1940-1574</eissn><abstract>The impact of peripheral artery disease (PAD) in patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study. We reviewed 3999 CTO PCIs performed in 3914 patients between 2012 and 2018 at 25 centers, 14% of whom had a history of PAD. We compared the clinical and angiographic characteristics and procedural outcomes of patients with versus without history of PAD. Patients with PAD were older (67 ± 9 vs 64 ± 10 years, P < .001) and had a higher prevalence of cardiovascular risk factors. They also had more complex lesions as illustrated by higher Japanese CTO score (2.7 ± 1.2 vs 2.4 ± 1.3, P < .001). In patients with PAD, the final crossing technique was less often antegrade wire escalation (40% vs 51%, P < .001) and more often the retrograde approach (23 vs 20%, P < .001) and antegrade dissection/reentry (20% vs 16%, P < .001). Technical success was similar between the 2 study groups (84% vs 87%, P = .127), but procedural success was lower for patients with PAD (81% vs 85%, P = .015). The incidence of in-hospital major adverse cardiac events was higher among patients with PAD (3% vs 2%, P = .046). In conclusion, patients with PAD undergoing CTO PCI have more comorbidities, more complex lesions, and lower procedural success.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>31845593</pmid><doi>10.1177/0003319719895178</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-9416-9701</orcidid><orcidid>https://orcid.org/0000-0002-5004-6635</orcidid></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0003-3197 |
ispartof | Angiology, 2020-03, Vol.71 (3), p.274-280 |
issn | 0003-3197 1940-1574 |
language | eng |
recordid | cdi_proquest_miscellaneous_2327938882 |
source | Access via SAGE; MEDLINE |
subjects | Adult Aged Chronic Disease Coronary Angiography - methods Coronary Occlusion - complications Coronary Occlusion - diagnostic imaging Coronary Occlusion - therapy Female Humans Male Middle Aged Percutaneous Coronary Intervention - methods Peripheral Arterial Disease - complications Peripheral Arterial Disease - surgery Registries Risk Factors Time Factors Treatment Outcome |
title | The Impact of Peripheral Artery Disease in Chronic Total Occlusion Percutaneous Coronary Intervention (Insights From PROGRESS-CTO Registry) |
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