Sarcoidosis: A great imitator
AbstractSarcoidosis is a chronic multisystemic, inflammatory disease with specific granulomatous cutaneous lesions. The cutaneous form may be considered a “great imitator,” due to its extensive clinical morphology that occurs in upwards of 20% to 35% of patients. Cutaneous lesions may have a variety...
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| Veröffentlicht in: | Clinics in dermatology 2019-05, Vol.37 (3), p.240-254 |
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| container_title | Clinics in dermatology |
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| creator | Karadağ, Ayşe Serap, MD Parish, Lawrence Charles, MD, MD (Hon) |
| description | AbstractSarcoidosis is a chronic multisystemic, inflammatory disease with specific granulomatous cutaneous lesions. The cutaneous form may be considered a “great imitator,” due to its extensive clinical morphology that occurs in upwards of 20% to 35% of patients. Cutaneous lesions may have a variety of presentations including papules, plaques, nodules, infiltrative scars, annular, angiolupoid, psoriasiform, hypopigmented, atrophic, ulcerative lesions, scarring and nonscarring alopecia, erythroderma, and ichthyosiform lesions. The dermatopathology is generally the same for all of the clinical presentations; however, variations in the cutaneous findings cause confusion in following a clinical course, therapeutic approach, or prognosis. |
| doi_str_mv | 10.1016/j.clindermatol.2019.01.005 |
| format | Article |
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The cutaneous form may be considered a “great imitator,” due to its extensive clinical morphology that occurs in upwards of 20% to 35% of patients. Cutaneous lesions may have a variety of presentations including papules, plaques, nodules, infiltrative scars, annular, angiolupoid, psoriasiform, hypopigmented, atrophic, ulcerative lesions, scarring and nonscarring alopecia, erythroderma, and ichthyosiform lesions. 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The cutaneous form may be considered a “great imitator,” due to its extensive clinical morphology that occurs in upwards of 20% to 35% of patients. Cutaneous lesions may have a variety of presentations including papules, plaques, nodules, infiltrative scars, annular, angiolupoid, psoriasiform, hypopigmented, atrophic, ulcerative lesions, scarring and nonscarring alopecia, erythroderma, and ichthyosiform lesions. The dermatopathology is generally the same for all of the clinical presentations; however, variations in the cutaneous findings cause confusion in following a clinical course, therapeutic approach, or prognosis.</description><subject>Adrenal Cortex Hormones - administration & dosage</subject><subject>Adrenocorticotropic Hormone - administration & dosage</subject><subject>Age of Onset</subject><subject>Antimalarials - therapeutic use</subject><subject>Biological Factors - therapeutic use</subject><subject>Dermatology</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>Humans</subject><subject>Infliximab - therapeutic use</subject><subject>Injections</subject><subject>Male</subject><subject>Mercaptopurine - analogs & derivatives</subject><subject>Mercaptopurine - therapeutic use</subject><subject>Methotrexate - therapeutic use</subject><subject>Prognosis</subject><subject>Rituximab - administration & dosage</subject><subject>Sarcoidosis - diagnosis</subject><subject>Sarcoidosis - epidemiology</subject><subject>Sarcoidosis - etiology</subject><subject>Sarcoidosis - pathology</subject><subject>Skin - pathology</subject><subject>Skin Diseases - diagnosis</subject><subject>Skin Diseases - etiology</subject><subject>Skin Diseases - pathology</subject><subject>Thalidomide - therapeutic use</subject><issn>0738-081X</issn><issn>1879-1131</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1LxDAQhoMoun78BGXx5KV1JmnTdg_C4jcseFgFbyGbTiRru12TVvDf27Iq4snTXJ55h3lexk4RYgSU58vYVG5Vkq9121QxByxiwBgg3WIjzLMiQhS4zUaQiTyCHJ_32H4ISwBIQMIu2xOIWY4gR-x4rr1pXNkEFybj6fjFk27HrnZtn-0P2Y7VVaCjr3nAnm6uHy_votnD7f3ldBaZRKRtVKZ5kiaFlNwUVhQJCJtaWXApwNjSauQ80zy1qA1YudCkEwt2wUmi0CIjccDONrlr37x1FFpVu2CoqvSKmi4oLnhWiDQReY9ONqjxTQierFp7V2v_oRDUoEct1W89atCjAFWvp18--brTLWoqf1a_ffTA1Qag_tt3R14F42hlqHSeTKvKxv3vzsWfmAF1Rlev9EFh2XR-1ftUqAJXoOZDUUNPWIi-pDQTn8s2kHU</recordid><startdate>20190501</startdate><enddate>20190501</enddate><creator>Karadağ, Ayşe Serap, MD</creator><creator>Parish, Lawrence Charles, MD, MD (Hon)</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20190501</creationdate><title>Sarcoidosis: A great imitator</title><author>Karadağ, Ayşe Serap, MD ; Parish, Lawrence Charles, MD, MD (Hon)</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c435t-d584549662c9f39403f5f692630cfdfa1227a25f1ac0f6baea4f0fb2e613a37e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adrenal Cortex Hormones - administration & dosage</topic><topic>Adrenocorticotropic Hormone - administration & dosage</topic><topic>Age of Onset</topic><topic>Antimalarials - therapeutic use</topic><topic>Biological Factors - therapeutic use</topic><topic>Dermatology</topic><topic>Diagnosis, Differential</topic><topic>Female</topic><topic>Humans</topic><topic>Infliximab - therapeutic use</topic><topic>Injections</topic><topic>Male</topic><topic>Mercaptopurine - analogs & derivatives</topic><topic>Mercaptopurine - therapeutic use</topic><topic>Methotrexate - therapeutic use</topic><topic>Prognosis</topic><topic>Rituximab - administration & dosage</topic><topic>Sarcoidosis - diagnosis</topic><topic>Sarcoidosis - epidemiology</topic><topic>Sarcoidosis - etiology</topic><topic>Sarcoidosis - pathology</topic><topic>Skin - pathology</topic><topic>Skin Diseases - diagnosis</topic><topic>Skin Diseases - etiology</topic><topic>Skin Diseases - pathology</topic><topic>Thalidomide - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Karadağ, Ayşe Serap, MD</creatorcontrib><creatorcontrib>Parish, Lawrence Charles, MD, MD (Hon)</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinics in dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Karadağ, Ayşe Serap, MD</au><au>Parish, Lawrence Charles, MD, MD (Hon)</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sarcoidosis: A great imitator</atitle><jtitle>Clinics in dermatology</jtitle><addtitle>Clin Dermatol</addtitle><date>2019-05-01</date><risdate>2019</risdate><volume>37</volume><issue>3</issue><spage>240</spage><epage>254</epage><pages>240-254</pages><issn>0738-081X</issn><eissn>1879-1131</eissn><abstract>AbstractSarcoidosis is a chronic multisystemic, inflammatory disease with specific granulomatous cutaneous lesions. The cutaneous form may be considered a “great imitator,” due to its extensive clinical morphology that occurs in upwards of 20% to 35% of patients. Cutaneous lesions may have a variety of presentations including papules, plaques, nodules, infiltrative scars, annular, angiolupoid, psoriasiform, hypopigmented, atrophic, ulcerative lesions, scarring and nonscarring alopecia, erythroderma, and ichthyosiform lesions. The dermatopathology is generally the same for all of the clinical presentations; however, variations in the cutaneous findings cause confusion in following a clinical course, therapeutic approach, or prognosis.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>31178106</pmid><doi>10.1016/j.clindermatol.2019.01.005</doi><tpages>15</tpages></addata></record> |
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| ispartof | Clinics in dermatology, 2019-05, Vol.37 (3), p.240-254 |
| issn | 0738-081X 1879-1131 |
| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Adrenal Cortex Hormones - administration & dosage Adrenocorticotropic Hormone - administration & dosage Age of Onset Antimalarials - therapeutic use Biological Factors - therapeutic use Dermatology Diagnosis, Differential Female Humans Infliximab - therapeutic use Injections Male Mercaptopurine - analogs & derivatives Mercaptopurine - therapeutic use Methotrexate - therapeutic use Prognosis Rituximab - administration & dosage Sarcoidosis - diagnosis Sarcoidosis - epidemiology Sarcoidosis - etiology Sarcoidosis - pathology Skin - pathology Skin Diseases - diagnosis Skin Diseases - etiology Skin Diseases - pathology Thalidomide - therapeutic use |
| title | Sarcoidosis: A great imitator |
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