The Melanocortin 4 Receptor p.Ile269Asn Mutation Is Associated with Childhood and Adult Obesity in Mexicans

Abstract Context Rare partial/complete loss-of-function mutations in the melanocortin-4 receptor (MC4R) gene are the most common cause of Mendelian obesity in European populations, but their contribution to obesity in the Mexican population is unclear. Objective and Design We investigated whether de...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2020-04, Vol.105 (4), p.e1468-e1477
Hauptverfasser:	Vázquez-Moreno, Miguel, Zeng, Helen, Locia-Morales, Daniel, Peralta-Romero, Jesús, Asif, Hamza, Maharaj, Arjuna, Tam, Vivian, Romero-Figueroa, María D S, Sosa-Bustamante, Gloria P, Méndez-Martínez, Socorro, Mejía-Benítez, Aurora, Valladares-Salgado, Adan, Wacher-Rodarte, Niels, Cruz, Miguel, Meyre, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adults Amino acids Biomarkers - analysis Body Mass Index Child Childhood Children Female Follow-Up Studies Genetic Predisposition to Disease Genotype Humans Isoleucine Male Melanocortin Melanocortin MC4 receptors Mexico - epidemiology Middle Aged Mutation Obesity Obesity - epidemiology Obesity - genetics Obesity - pathology Pedigree Phenotype Population Prognosis Receptor, Melanocortin, Type 4 - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!