Antihypertensive Effects in Vitro and in Vivo of Novel Angiotensin-Converting Enzyme Inhibitory Peptides from Bovine Bone Gelatin Hydrolysate

In this study, we investigated the antihypertensive effects in vitro and in vivo of novel angiotensin-converting enzyme inhibitory (ACEI) peptides purified and identified from bovine bone gelatin hydrolysate (BGH). Thirteen ACEI peptides were identified from BGH, and among which, RGL-(Hyp)-GL and RG...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2020-01, Vol.68 (3), p.759-768
Hauptverfasser:	Cao, Songmin, Wang, Yi, Hao, Yuejing, Zhang, Wangang, Zhou, Guanghong
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-Converting Enzyme Inhibitors - administration & dosage Angiotensin-Converting Enzyme Inhibitors - chemistry Angiotensin-Converting Enzyme Inhibitors - isolation & purification Animals Antihypertensive Agents - administration & dosage Antihypertensive Agents - chemistry Antihypertensive Agents - isolation & purification Blood Pressure - drug effects Bone and Bones - chemistry Cattle Gelatin - chemistry Humans Hypertension - drug therapy Hypertension - physiopathology Male Molecular Docking Simulation Peptides - administration & dosage Peptides - chemistry Peptides - isolation & purification Peptidyl-Dipeptidase A - chemistry Protein Hydrolysates - chemistry Rats Rats, Inbred SHR
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