Simultaneous EEG/fMRI recorded during ketamine infusion in patients with major depressive disorder

A single subanaesthetic dose of ketamine rapidly alleviates the symptoms of major depressive disorder (MDD). However, few studies have investigated the acute effects of ketamine on the BOLD pharmacological magnetic resonance imaging (phMRI) response and EEG spectra. In a randomised, double-blind, ac...

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Veröffentlicht in:	Progress in neuro-psychopharmacology & biological psychiatry 2020-04, Vol.99, p.109838-109838, Article 109838
Hauptverfasser:	McMillan, Rebecca, Sumner, Rachael, Forsyth, Anna, Campbell, Doug, Malpas, Gemma, Maxwell, Elizabeth, Deng, Carolyn, Hay, John, Ponton, Rhys, Sundram, Frederick, Muthukumaraswamy, Suresh
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anesthetics, Dissociative - administration & dosage Cross-Over Studies Depression Depressive Disorder, Major - diagnostic imaging Depressive Disorder, Major - drug therapy Depressive Disorder, Major - physiopathology Double-Blind Method EEG Electroencephalography - drug effects Electroencephalography - methods Female fMRI Humans Infusions, Intravenous Ketamine Ketamine - administration & dosage Magnetic Resonance Imaging - methods Male Middle Aged Young Adult
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