Efficacy and Safety of Approved First-Line Tyrosine Kinase Inhibitor Treatments in Metastatic Renal Cell Carcinoma: A Network Meta-Analysis

Introduction This network meta-analysis aims to deliver an up-to-date, comprehensive efficacy and toxicity comparison of the approved first-line tyrosine kinase inhibitors (TKIs) for metastatic renal cell carcinoma (mRCC) in order to provide support for evidence-based treatment decisions. Previous N...

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Veröffentlicht in:	Advances in therapy 2020-02, Vol.37 (2), p.730-744
Hauptverfasser:	Manz, Kirsi M., Fenchel, Klaus, Eilers, Andreas, Morgan, Jonathan, Wittling, Kirsten, Dempke, Wolfram C. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Anilides - therapeutic use Antineoplastic Agents - therapeutic use Carcinoma, Renal Cell - drug therapy Cardiology Endocrinology Female Humans Internal Medicine Kidney Neoplasms - drug therapy Life Sciences & Biomedicine Male Medicine Medicine & Public Health Medicine, Research & Experimental Middle Aged Neoplasm Metastasis - drug therapy Network Meta-Analysis Oncology Original Research Pharmacology & Pharmacy Pharmacology/Toxicology Phenylurea Compounds - therapeutic use Progression-Free Survival Protein Kinase Inhibitors - therapeutic use Pyridines - therapeutic use Pyrimidines - therapeutic use Quinolines - therapeutic use Research & Experimental Medicine Rheumatology Science & Technology Sulfonamides - therapeutic use Sunitinib - therapeutic use
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