Identification of Calculus Bovis and its mixed varieties by ultra-high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UHPLC-Q/TOF-MS) combined with the principal component analysis (PCA) method

•The mixed solvent system can be used to extract the chemical composition of the sample to the maximum extent.•The run time of each sample was 52 min by UHPLC-Q-TOF/MS.•UHPLC-Q/TOF-MS, Progenesis QI and Makerlynx XS software were integrated to clarify the difference of chemical components from Calcu...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2020-02, Vol.179, p.112979-112979, Article 112979
Hauptverfasser:	Liu, Wen-Xi, Cheng, Xian-Long, Guo, Xiao-han, Hu, Xiao-ru, Wei, Feng, Ma, Shuang-Cheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Products - analysis Calculus Bovis Characteristic components Chromatography, High Pressure Liquid - methods Identification In vitro cultured Calculus bovis Medicine, Chinese Traditional - standards PCA Principal Component Analysis - methods QqQ-MS Software Tandem Mass Spectrometry - methods UHPLC-QTOF-MS
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