Influence of contrast agent dispersion on bolus‐based MRI myocardial perfusion measurements: A computational fluid dynamics study

Purpose Bolus‐based dynamic contrast agent (CA) perfusion measurements of the heart are subject to systematic errors due to CA bolus dispersion in the coronary arteries. To better understand these effects on quantification of myocardial blood flow and myocardial perfusion reserve (MPR), an in‐silico...

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Veröffentlicht in:	Magnetic resonance in medicine 2020-07, Vol.84 (1), p.467-483
Hauptverfasser:	Martens, Johannes, Panzer, Sabine, den Wijngaard, Jeroen, Siebes, Maria, Schreiber, Laura M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arteries Blood flow Blood vessels bolus‐based perfusion measurement Boundary conditions Computational fluid dynamics Computer applications Computer simulation Concentration time Contrast agents Contrast Media Coronary artery Coronary Artery Disease Coronary Circulation Coronary vessels Diameters Dispersion Flow velocity Fluid dynamics Hydrodynamics Magnetic Resonance Imaging Mathematical analysis myocardial blood flow Myocardial Perfusion Imaging myocardial perfusion reserve Perfusion Swine Systematic errors Three dimensional models Transport
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