Comprehensive geriatric assessment is correlated to overall survival among gynaecologic oncology patients
Abstract Objective To investigate the correlation of comprehensive geriatric assessment to overall survival among older gynaecologic oncology patients. Methods Between 2011 and 2017, patients >70 years had geriatric assessment before treatment. Geriatric assessment included the following tests: O...
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| Veröffentlicht in: | Japanese journal of clinical oncology 2020-03, Vol.50 (3), p.276-281 |
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| container_title | Japanese journal of clinical oncology |
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| creator | Michaan, Nadav Park, Sang Yoon Lim, Myong Cheol |
| description | Abstract
Objective
To investigate the correlation of comprehensive geriatric assessment to overall survival among older gynaecologic oncology patients.
Methods
Between 2011 and 2017, patients >70 years had geriatric assessment before treatment. Geriatric assessment included the following tests: Old American resource and services, instrumental activities of daily living, modified Barthels index, mini-mental state examination, geriatric depression scale, mini-nutritional assessment, risk of falling and medication use. Overall survival was calculated for patients’ groups below and above median tests scores. Univariate as well as multivariate analysis was done to evaluate the association between each variable and survival.
Results
About 120 patients had geriatric assessment. Mean patients’ age was 76.4 ± 5. A total of 78 Patients had ovarian cancer, 16 uterine cancer, 17 cervical cancer and 9 had other gynaecologic malignancies. No correlation was found between age, BMI (body mass index) and cancer type to overall survival. Patients with scores below cut-off values of modified Barthels index, instrumental activities of daily living, mini-nutritional assessment and mini-nutritional assessment had significantly shorter overall survival (P = 0.004, 0.031, 0.046 and 0.004, respectively). This remained significant in both univariate and multivariate analysis.
Conclusions
Gynaecologic oncology patients with lower geriatric assessment scores have significantly lower overall survival, irrespective of cancer type. Geriatric assessment tests allow objective assessment of older patients with worst prognosis before treatment planning.
Comprehensive geriatric assessment offers multidimensional assessment of gynaecologic oncologic patients. Elderly gynaecologic oncology patients with lower comprehensive geriatric assessment scores have lower overall survival. |
| doi_str_mv | 10.1093/jjco/hyz178 |
| format | Article |
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Objective
To investigate the correlation of comprehensive geriatric assessment to overall survival among older gynaecologic oncology patients.
Methods
Between 2011 and 2017, patients >70 years had geriatric assessment before treatment. Geriatric assessment included the following tests: Old American resource and services, instrumental activities of daily living, modified Barthels index, mini-mental state examination, geriatric depression scale, mini-nutritional assessment, risk of falling and medication use. Overall survival was calculated for patients’ groups below and above median tests scores. Univariate as well as multivariate analysis was done to evaluate the association between each variable and survival.
Results
About 120 patients had geriatric assessment. Mean patients’ age was 76.4 ± 5. A total of 78 Patients had ovarian cancer, 16 uterine cancer, 17 cervical cancer and 9 had other gynaecologic malignancies. No correlation was found between age, BMI (body mass index) and cancer type to overall survival. Patients with scores below cut-off values of modified Barthels index, instrumental activities of daily living, mini-nutritional assessment and mini-nutritional assessment had significantly shorter overall survival (P = 0.004, 0.031, 0.046 and 0.004, respectively). This remained significant in both univariate and multivariate analysis.
Conclusions
Gynaecologic oncology patients with lower geriatric assessment scores have significantly lower overall survival, irrespective of cancer type. Geriatric assessment tests allow objective assessment of older patients with worst prognosis before treatment planning.
Comprehensive geriatric assessment offers multidimensional assessment of gynaecologic oncologic patients. Elderly gynaecologic oncology patients with lower comprehensive geriatric assessment scores have lower overall survival.</description><identifier>ISSN: 1465-3621</identifier><identifier>EISSN: 1465-3621</identifier><identifier>DOI: 10.1093/jjco/hyz178</identifier><identifier>PMID: 31822898</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><ispartof>Japanese journal of clinical oncology, 2020-03, Vol.50 (3), p.276-281</ispartof><rights>The Author(s) 2019. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com 2019</rights><rights>The Author(s) 2019. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c381t-95ab9b55e2be67d53b2edb22cca9d1b6ec4b0bdcdcce2573882157a7063c6b5a3</citedby><cites>FETCH-LOGICAL-c381t-95ab9b55e2be67d53b2edb22cca9d1b6ec4b0bdcdcce2573882157a7063c6b5a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1578,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31822898$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Michaan, Nadav</creatorcontrib><creatorcontrib>Park, Sang Yoon</creatorcontrib><creatorcontrib>Lim, Myong Cheol</creatorcontrib><title>Comprehensive geriatric assessment is correlated to overall survival among gynaecologic oncology patients</title><title>Japanese journal of clinical oncology</title><addtitle>Jpn J Clin Oncol</addtitle><description>Abstract
Objective
To investigate the correlation of comprehensive geriatric assessment to overall survival among older gynaecologic oncology patients.
Methods
Between 2011 and 2017, patients >70 years had geriatric assessment before treatment. Geriatric assessment included the following tests: Old American resource and services, instrumental activities of daily living, modified Barthels index, mini-mental state examination, geriatric depression scale, mini-nutritional assessment, risk of falling and medication use. Overall survival was calculated for patients’ groups below and above median tests scores. Univariate as well as multivariate analysis was done to evaluate the association between each variable and survival.
Results
About 120 patients had geriatric assessment. Mean patients’ age was 76.4 ± 5. A total of 78 Patients had ovarian cancer, 16 uterine cancer, 17 cervical cancer and 9 had other gynaecologic malignancies. No correlation was found between age, BMI (body mass index) and cancer type to overall survival. Patients with scores below cut-off values of modified Barthels index, instrumental activities of daily living, mini-nutritional assessment and mini-nutritional assessment had significantly shorter overall survival (P = 0.004, 0.031, 0.046 and 0.004, respectively). This remained significant in both univariate and multivariate analysis.
Conclusions
Gynaecologic oncology patients with lower geriatric assessment scores have significantly lower overall survival, irrespective of cancer type. Geriatric assessment tests allow objective assessment of older patients with worst prognosis before treatment planning.
Comprehensive geriatric assessment offers multidimensional assessment of gynaecologic oncologic patients. Elderly gynaecologic oncology patients with lower comprehensive geriatric assessment scores have lower overall survival.</description><issn>1465-3621</issn><issn>1465-3621</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kDtPwzAURi0EoqUwsSNPCAmFxnacOCOqeEmVWGCObOc2dZXEwU4ihV9PSgpiYrrfcO4ZDkKXJLwjYcqWu522y-3wSRJxhOYkinnAYkqO_-wZOvN-F4YhF1FyimaMCEpFKubIrGzVONhC7U0PuABnZOuMxtJ78L6CusXGY22dg1K2kOPWYtuDk2WJfed608sSy8rWBS6GWoK2pS3Gf1t_rwE3sjWjxZ-jk40sPVwc7gK9Pz68rZ6D9evTy-p-HWgmSBukXKpUcQ5UQZzknCkKuaJUa5nmRMWgIxWqXOdaA-UJE4ISnsgkjJmOFZdsgW4mb-PsRwe-zSrjNZSlrMF2PqOMRimhgsUjejuh2lnvHWyyxplKuiEjYbZvm-3bZlPbkb46iDtVQf7L_sQcgesJsF3zr-kLSlCHWQ</recordid><startdate>20200309</startdate><enddate>20200309</enddate><creator>Michaan, Nadav</creator><creator>Park, Sang Yoon</creator><creator>Lim, Myong Cheol</creator><general>Oxford University Press</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20200309</creationdate><title>Comprehensive geriatric assessment is correlated to overall survival among gynaecologic oncology patients</title><author>Michaan, Nadav ; Park, Sang Yoon ; Lim, Myong Cheol</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c381t-95ab9b55e2be67d53b2edb22cca9d1b6ec4b0bdcdcce2573882157a7063c6b5a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Michaan, Nadav</creatorcontrib><creatorcontrib>Park, Sang Yoon</creatorcontrib><creatorcontrib>Lim, Myong Cheol</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Japanese journal of clinical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Michaan, Nadav</au><au>Park, Sang Yoon</au><au>Lim, Myong Cheol</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comprehensive geriatric assessment is correlated to overall survival among gynaecologic oncology patients</atitle><jtitle>Japanese journal of clinical oncology</jtitle><addtitle>Jpn J Clin Oncol</addtitle><date>2020-03-09</date><risdate>2020</risdate><volume>50</volume><issue>3</issue><spage>276</spage><epage>281</epage><pages>276-281</pages><issn>1465-3621</issn><eissn>1465-3621</eissn><abstract>Abstract
Objective
To investigate the correlation of comprehensive geriatric assessment to overall survival among older gynaecologic oncology patients.
Methods
Between 2011 and 2017, patients >70 years had geriatric assessment before treatment. Geriatric assessment included the following tests: Old American resource and services, instrumental activities of daily living, modified Barthels index, mini-mental state examination, geriatric depression scale, mini-nutritional assessment, risk of falling and medication use. Overall survival was calculated for patients’ groups below and above median tests scores. Univariate as well as multivariate analysis was done to evaluate the association between each variable and survival.
Results
About 120 patients had geriatric assessment. Mean patients’ age was 76.4 ± 5. A total of 78 Patients had ovarian cancer, 16 uterine cancer, 17 cervical cancer and 9 had other gynaecologic malignancies. No correlation was found between age, BMI (body mass index) and cancer type to overall survival. Patients with scores below cut-off values of modified Barthels index, instrumental activities of daily living, mini-nutritional assessment and mini-nutritional assessment had significantly shorter overall survival (P = 0.004, 0.031, 0.046 and 0.004, respectively). This remained significant in both univariate and multivariate analysis.
Conclusions
Gynaecologic oncology patients with lower geriatric assessment scores have significantly lower overall survival, irrespective of cancer type. Geriatric assessment tests allow objective assessment of older patients with worst prognosis before treatment planning.
Comprehensive geriatric assessment offers multidimensional assessment of gynaecologic oncologic patients. Elderly gynaecologic oncology patients with lower comprehensive geriatric assessment scores have lower overall survival.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>31822898</pmid><doi>10.1093/jjco/hyz178</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| title | Comprehensive geriatric assessment is correlated to overall survival among gynaecologic oncology patients |
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