Drug delivery to macrophages: A review of targeting drugs and drug carriers to macrophages for inflammatory diseases

Macrophages play a key role in defending against foreign pathogens, healing wounds, and regulating tissue homeostasis. Driving this versatility is their phenotypic plasticity, which enables macrophages to respond to subtle cues in tightly coordinated ways. However, when this coordination is disrupte...

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Veröffentlicht in:	Advanced drug delivery reviews 2020, Vol.165-166, p.15-40
Hauptverfasser:	He, Wei, Kapate, Neha, Shields, C. Wyatt, Mitragotri, Samir
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoimmune disease Autoimmune Diseases - drug therapy Autoimmune Diseases - physiopathology Cardiovascular disease Cytokines - biosynthesis Drug Carriers Drug delivery Drug Delivery Systems - methods Humans Inflammation Inflammation - drug therapy Inflammation - physiopathology Inflammation Mediators - immunology Macrophages Macrophages - immunology Monocytes - metabolism Neoplasms - drug therapy Neoplasms - physiopathology Solid tumors Tumor Microenvironment Tumor-Associated Macrophages - immunology
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