Effects of Yukmijihwang-tang, a Polyherb, on the Pharmacokinetics of Metformin

Metformin is one of the most common medicines for the treatment of type 2 diabetes, however, recent studies suggest that concomitant antihyperglycemic agents should be administered for better efficacy. Yukmijihwang-tang (YMJHT) is a nephroprotective polyherb prescribed for renal disorders or diabeti...

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Veröffentlicht in:	Pakistan journal of pharmaceutical sciences 2019-09, Vol.32 (5), p.2025-2031
Hauptverfasser:	Kang, Seok Bong, Shon, Ho Sang, Park, Soo Jin, Lee, Young Joon, Ku, Sae-Kwang, Song, Chang-Hyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Area Under Curve Combination drug therapy Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - metabolism Diabetes therapy Drug Therapy, Combination - adverse effects Drugs, Chinese Herbal - pharmacology Herb-Drug Interactions - physiology Hypoglycemic agents Hypoglycemic Agents - pharmacokinetics Hypoglycemic Agents - pharmacology Male Metformin Metformin - pharmacokinetics Metformin - pharmacology Plants, Medicinal - adverse effects Rats Rats, Sprague-Dawley Type 2 diabetes Water
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