The effects of aspirin gel and mouthwash on levels of salivary biomarkers PGE2, TNF-α and nitric oxide in patients with periodontal diseases

Inflammation and its mediators have an important role in gingivitis and periodontitis. Prostaglandin is one of the eicosanoid involved in many chronic inflammatory diseases, including periodontal diseases. Aspirin irreversibly acetylates cyclooxygenase and inactivate this enzyme responsible for the...

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Veröffentlicht in:	Pakistan journal of pharmaceutical sciences 2019-09, Vol.32 (5), p.2019-2023
Hauptverfasser:	Hasan, Faiza, Ikram, Rahila, Simjee, Shabana Usman, Iftakhar, Kanwal, Asadullah, Kamran, Usman, Mohd
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-Inflammatory Agents - pharmacology Aspirin - pharmacology Biomarkers - metabolism Dinoprostone - metabolism Female Gels - pharmacology Gingivitis - drug therapy Gingivitis - metabolism Humans Inflammation Mediators - metabolism Male Mouthwashes - pharmacology Nitric Oxide - metabolism Periodontal Diseases - drug therapy Periodontal Diseases - metabolism Periodontitis - drug therapy Periodontitis - metabolism Saliva - drug effects Saliva - metabolism Tumor Necrosis Factor-alpha - metabolism Young Adult
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